S-14,506
Appearance
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Names | |
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Preferred IUPAC name
4-Fluoro-N-{2-[4-(7-methoxynaphthalen-1-yl)piperazin-1-yl]ethyl}benzamide | |
Identifiers | |
3D model (JSmol)
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ChEBI | |
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PubChemCID
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UNII | |
CompTox Dashboard(EPA)
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Properties | |
C24H26FN3O2 | |
Molar mass | 407.489g·mol−1 |
Except where otherwise noted, data are given for materials in theirstandard state(at 25 °C [77 °F], 100 kPa).
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S-14,506is anaphthylpiperazine,a5-HT1A receptoragonist,[1]and adopamine receptorantagonist.[2]
References[edit]
- ^Milligan, G.; Kellett, E.; Dacquet, C.; Dubreuil, V.; Jacoby, E.; Millan, M. J.; Lavielle, G.; Spedding, M. (2001). "S 14506: Novel receptor coupling at 5-HT(1A) receptors".Neuropharmacology.40(3): 334–344.doi:10.1016/s0028-3908(00)00162-3.PMID11166326.S2CID36060096.
- ^Protais, P.; Chagraoui, A.; Arbaoui, J.; Mocaër, E. (1994). "Dopamine receptor antagonist properties of S 14506, 8-OH-DPAT, raclopride and clozapine in rodents".European Journal of Pharmacology.271(1): 167–177.doi:10.1016/0014-2999(94)90277-1.PMID7698199.