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sCMOS(scientific Complementary Metal–Oxide–Semiconductor) are a type ofCMOS image sensor(CIS).[1]These sensors are commonly used as components in specific observational scientific instruments, such asmicroscopes[2]andtelescopes.[3]sCMOS image sensors offer extremely low noise, rapidframe rates,widedynamic range,high quantum efficiency,high resolution,and a large field of view simultaneously in one image.[4][5]

The sCMOS technology was launched in 2009 during theLaser World of Photonicsfair in Munich. The companiesAndor Technology,Fairchild ImagingandPCO Imagingdeveloped the technology forimage sensorsas ajoint venture.[6][4]

Technical details

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Prior to the introduction of the technology, scientists were limited to using eitherCCDorEMCCD cameras,both of which had their own set of technical limitations.[7]While back-illuminated electron-multiplying CCD (EMCCD) cameras are optimal for purposes requiring the lowest noise and dark currents, sCMOS technology's higher pixel count and lower cost result in its use in a wide range of precision applications. sCMOS devices can capture data in a global-shutter “snapshot” mode over all the pixels or rectangular subsets of pixels, and can also operate in a rolling-shutter mode.[8][1]

The cameras are available with amonochrome sCMOS image sensorsor withRGB sCMOS image sensors.With sCMOS, digital information for each frame is generated rapidly and with an improved low-light image quality. The sCMOS sensor's low read noise and larger area provides a low-noise, largefield-of-view(FOV) image that enables researchers to scan across a sample and capture high-quality images.[9][5]

Some disadvantages at this time, (2023), with sCMOS cameras versus related technologies are:

  • sCMOS sensors tend be more expensive than traditional CMOS sensors.
  • sCMOS sensors have a limited resolution compared to other types of sensors like CCD.[10]
Comparison - CCD vs. sCMOS technology; lower figure compares a scientific grade CCD (left) and a pco.edge camera with sCMOS sensor (on the right) under similar weak illumination conditions. This demonstrates the superiority of sCMOS over CCD with regards to read out noise and dynamic, without smear (the vertical lines in the CCD image).

In practice

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TheNew York University School of Medicineuses sCMOS cameras for their research. They were used to study biological molecules and processes in real-time atnanometer scale.[1]Such cameras were also in use in astronomy andmicroscopy.[11]

See also

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References

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  1. ^abc"Photonics Products: Scientific CMOS Cameras: sCMOS cameras reach new levels of capability".Laser Focus World.2018.
  2. ^"A Comparison of EMCCD vs sCMOS Cameras".Oxford Instruments.Retrieved2021-09-04.
  3. ^Walker, G. E. (2020-01-01)."Will sCMOS replace CCD's for Astronomy?".American Astronomical Society Meeting Abstracts #235.235:175.01.Bibcode:2020AAS...23517501W.
  4. ^ab"Photonics Products: Scientific CMOS Cameras: sCMOS cameras reach new levels of capability".Photonics Online. 2012.
  5. ^abEvaluation of sCMOS cameras for detection and localization of single Cy5 molecules,Optics Express, Saumya Saurabh, Suvrajit Maji, and Marcel P. Bruchez, 2012.
  6. ^sCMOS – Die eierlegende Wollmilchsau der Bildsensorik?,Wiley-VCH,Gerhard Holst, German, 2009
  7. ^sCMOS Cameras Take the Scientific Imaging Stage,May 7, 2018. Retrieved on October 8, 2018
  8. ^scmos.comArchived2012-06-03 at theWayback Machine,home page
  9. ^How to Choose Between a CCD and sCMOS Scientific-Grade Camera,American Laboratory, April 29, 2015. Retrieved November 4, 2018.
  10. ^Kumar, Prabu (2023-04-26)."The ultimate image sensor guide: EMCCD vs. SCMOS vs. CMOS vs. CCD".e-con Systems.Retrieved2023-07-22.
  11. ^"StackPath".www.laserfocusworld.com.2 May 2018.Retrieved2020-06-10.

Further reading

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