Sialic acid-binding Ig-like lectin 10is aproteinthat in humans is encoded by theSIGLEC10gene.[5][6]Siglec-G is often referred to as the murine paralog of human Siglec-10[7]
SIGLECsare members of the immunoglobulin superfamily that are expressed on the cell surface. Most SIGLECs have 1 or more cytoplasmic immune receptor tyrosine-based inhibitory motifs, or ITIMs. SIGLECs are typically expressed on cells of the innate immune system, with the exception of the B-cell expressed SIGLEC6 (MIM 604405).[supplied by OMIM][6]
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