SOX2 overlapping transcript (SOX2OT) is along non-coding RNA,containing at least 5exons.TheSOX2gene, an important regulator ofneurogenesis,lies within one of theintronsof SOX2OT.[3]SOX2OT and SOX2DOT (anisoformof SOXOT transcribed from a distal highly conserved element) are expressed in zones of neurogenesis within the brain. It is associated withcentral nervous systemstructures inzebrafishand chicken embryonic brains, and is dynamically regulated duringembryogenesis.[4]SOX2OT may play a role in vertebrate development.[4]