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Sensodyne

From Wikipedia, the free encyclopedia
Sensodyne
Sensodyne twin sachet
(in the Philippines)
Product typeToothpaste
OwnerHaleon
CountryUnited States
Introduced1961;63 years ago(1961)
Related brandsAquafresh
Biotene
MarketsWorldwide
Previous owners
Websitewww.sensodyne.com

Sensodyneis a brand name oftoothpasteandmouthwashtargeted at people withsensitive teeth.[1]Sensodyne is owned byHaleonand is marketed under the name Shumitect inJapan.[2]

Effectiveness

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Sensodyne toothpastes work in different ways depending on the product's active ingredient—potassium nitrate, strontium acetate/chloride.

Potassium nitrate:The potassium ion hyperpolarizes[3]the nerve and stops it from firing. The nerve impulses are thus desensitized and there is no pain.

Strontium acetate andstrontium chloride:These compounds share a similar chemical structure to calcium.Strontiumbased toothpastes (acetate and chloride) are therefore able to replace some of the lost calcium and block the exposed tubules in the dentinal tissue. This helps prevent the movement of the fluid within the tubules in response to a sensitivity stimulus that could otherwise cause tooth pain.[4]

Some Sensodyne products containcalcium sodium phosphosilicateCSPS (Novamin), which appears to help with tooth sensitivity.[5][6]A randomized clinical trial published in 2015 demonstrated that dentifrices containing 5% CSPS may have the potential to mineralize and occlude the dentine in the oral environment.[7][8]Sensodyne products sold in the United States do not contain calcium sodium phosphosilicate (Novamin).[9]

History

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Sensodyne is a brand of toothpaste that was first sold byBlock Drug,aBrooklyn,New York-based company established in 1907 by pharmacist Alexander Block.[1]

By 1925, manufacturing dental care products had become the company's focus. Leonard N. Block followed his father into the family business which relocated toJersey City,New Jersey,in 1938.[10]

In 2000, Block Drug was purchased by Smith Kline Beecham P.L.C.,[11]which becameGlaxoSmithKline(NYSE:GSK).[12]

The toothpaste was first marketed in 1961 as a desensitisingtoothpastebased on a strontium chloride formulation.[citation needed]In 1980,[citation needed]Sensodyne launched a new toothpaste containingpotassium nitrate,a mild localsedative.[13]

Sensodyne became a part ofHaleon,a British multinational consumer healthcare corporation, in July 2022, following the establishment of Haleon as a separate entity through a corporate spin-off from GSK.[14]

Product counterfeits and recall

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In 2007,GlaxoSmithKlinetracked down counterfeit producers of Sensodyne after a consumer in Panama noteddiethylene glycol,a poisonous ingredient commonly found in antifreeze, on the label of his toothpaste.[15]

On July 15, 2015,GlaxoSmithKlineConsumer Healthcare announced a recall of certain lots of Sensodyne Repair & Protect toothpaste as well as Sensodyne Complete toothpaste due to the possible presence of wood fragments in the products. The recall also applied to the company's Biotene brand of toothpaste. The recall was a precautionary measure based on a small number of complaints, and no injuries have been reported. The recall applies to products manufactured between 2013 and September 2014, and shipped from June 2013 to April 2015.[16]

See also

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References

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  1. ^abClark, Andrew (October 7, 2000)."SmithKline to swallow Sensodyne".The Guardian.Archivedfrom the original on October 25, 2019.RetrievedJuly 20,2013.
  2. ^"Sensodyne | Our consumer healthcare products | Products | GlaxoSmithKline".Archived fromthe originalon 2013-03-05.Retrieved2013-03-17.
  3. ^Walsh, Margaret (Apr 15, 2014).Dental Hygiene: Theory and Practice.Elsevier Health Sciences. p. 699.ISBN9781455745845.Archivedfrom the original on February 27, 2024.RetrievedNovember 5,2020.
  4. ^Hughes, N; Layer, T (2010). "Evidence for the efficacy of an 8% strontium acetate dentifrice for instant and lasting relief of dentin hypersensitivity".Journal of Clinical Dentistry.21(5): 56–58.PMID20669817.
  5. ^Freda, Nicolas M; Veitz-Keenan, Analia (March 2016). "Calcium sodium phosphosilicate had some benefit on dentine hypersensitivity: Question: Is calcium sodium phosphosilicate (CSPS) effective in reducing dentine hypersensitivity (DH) pain response?".Evidence-Based Dentistry.17(1): 12–13.doi:10.1038/sj.ebd.6401148.PMID27012568.S2CID24049298.
  6. ^Goldie, Maria (15 March 2011)."Potassium nitrate, sodium fluoride, strontium chloride, and NovaMin technologies for dentin hypersensitivity".Dentistry IQ.Archivedfrom the original on 25 October 2019.Retrieved21 November2014.
  7. ^Jones, Siân Bodfel; Parkinson, Charles R.; Jeffery, Peter; Davies, Maria; Macdonald, Emma L.; Seong, Joon; West, Nicola X. (June 2015). "A randomised clinical trial investigating calcium sodium phosphosilicate as a dentine mineralising agent in the oral environment".Journal of Dentistry.43(6): 757–764.doi:10.1016/j.jdent.2014.10.005.PMID25456613.
  8. ^Hall, Claire; Mason, Stephen; Cooke, Jonathan (May 2017)."Exploratory randomised controlled clinical study to evaluate the comparative efficacy of two occluding toothpastes – a 5% calcium sodium phosphosilicate toothpaste and an 8% arginine/calcium carbonate toothpaste – for the longer-term relief of dentine hypersensitivity".Journal of Dentistry.60:36–43.doi:10.1016/j.jdent.2017.02.009.PMID28219674.
  9. ^United States National Institutes of Health, National Library of Medicine,SENSODYNE REPAIR AND PROTECT – stannous fluoride pasteArchived2021-09-20 at theWayback Machine.
  10. ^Saxon, Wolfgang (2005-11-12)."Leonard Block, 93, Chief of Drug Company, Is Dead".The New York Times.ISSN0362-4331.Archivedfrom the original on 2019-09-30.Retrieved2019-09-30.
  11. ^"Company News; Smithkline to Buy Block Drug for $1.2 Billion".The New York Times.2000-10-10.ISSN0362-4331.Archivedfrom the original on 2019-04-02.Retrieved2019-09-30.
  12. ^"Firms Complete Merger of GlaxoSmithKline".Los Angeles Times.2000-12-28.Archivedfrom the original on 2019-09-30.Retrieved2019-09-30.
  13. ^Ramirez, Anthony (May 13, 1990)."All About/Toothpaste; Growth Is Glacial, but the Market Is Big, and So Is the Gross".The New York Times.Archivedfrom the original on August 26, 2014.RetrievedJuly 20,2013.
  14. ^Khalaf, Roula (5 May 2023)."Healthy return proves worth of Haleon spin-out".Financial Times.Archivedfrom the original on 23 November 2023.Retrieved23 November2023.
  15. ^Colgate and Sensodyne, got caught up in the sweep when counterfeiters were found to be selling toothpaste with antifreeze under their names.BOGDANICH, WALT (October 1, 2007)."The Everyman Who Exposed Tainted Toothpaste".The New York Times.Archivedfrom the original on 16 January 2018.Retrieved2 April2019.
  16. ^"Urgent: Product Recall – Retail Level"(PDF).Smith Drug.15 July 2015.Archived(PDF)from the original on 7 August 2015.Retrieved21 August2015.
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