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Spumaretrovirinae

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Spumaretrovirinae
Virus classificationEdit this classification
(unranked): Virus
Realm: Riboviria
Kingdom: Pararnavirae
Phylum: Artverviricota
Class: Revtraviricetes
Order: Ortervirales
Family: Retroviridae
Subfamily: Spumaretrovirinae
Genera[1]

Spumaretrovirinae,commonly calledspumaviruses(spuma,Latinfor "foam" ) orfoamyviruses,is a subfamily of theRetroviridaefamily.[2]Spumaviruses areexogenousviruses that have specificmorphologywith prominent surfacespikes.Thevirionscontain significant amounts of double-stranded full-lengthDNA,and assembly is rather unusual in these viruses. Spumaviruses are unlike most enveloped viruses in that theenvelopemembrane is acquired bybuddingthrough theendoplasmic reticuluminstead of thecytoplasmic membrane.Some spumaviruses, including the equine foamy virus (EFV), bud from the cytoplasmic membrane.

Some examples of these viruses aresimian foamy virusand thehuman foamy virus.

While spumaviruses will form characteristic large vacuoles in their host cells whilein vitro,there is no disease associationin vivo.[3]

References

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  1. ^"Virus Taxonomy: 2018b Release".International Committee on Taxonomy of Viruses (ICTV).March 2019.Retrieved16 March2019.
  2. ^ICTV:Master Species List 2018a v1MSL including all taxa updates since the 2017 release. Fall 2018 (MSL #33)
  3. ^Acheson, NH (2007).Fundamentals of Molecular Virology(1st ed.). Wiley.ISBN978-0-471-35151-1.

Further reading

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  • Santillana-Hayat M, Valla J, Canivet M, Peries J, Molina JM (1996). "Inhibition of the in vitro infectivity and cytopathic effect of human foamy virus by dideoxynucleosides".AIDS Res Hum Retroviruses.12(15): 1485–90.doi:10.1089/aid.1996.12.1485.PMID8893056.
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