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Dyclonine

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Dyclonine
Clinical data
Trade namesSucrets
AHFS/Drugs.comMonograph
Routes of
administration
Lozenge
ATC code
Legal status
Legal status
Identifiers
  • 1-(4-butoxyphenyl)-3-(1-piperidyl)propan-1-one
CAS Number
PubChemCID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard(EPA)
Chemical and physical data
FormulaC18H27NO2
Molar mass289.419g·mol−1
3D model (JSmol)
  • O=C(c1ccc(OCCCC)cc1)CCN2CCCCC2
  • InChI=1S/C18H27NO2/c1-2-3-15-21-17-9-7-16(8-10-17)18(20)11-14-19-12-5-4-6-13-19/h7-10H,2-6,11-15H2,1H3checkY
  • Key:BZEWSEKUUPWQDQ-UHFFFAOYSA-NcheckY
☒NcheckY(what is this?)(verify)

Dyclonine(Dyclocaine) is an oralanaestheticthat is the active ingredient ofSucrets,anover-the-counterthroat lozenge.[1]It is also found in some varieties of theCepacolsore throatspray. It is a local anesthetic, used topically as the hydrochloride salt.[2]

History

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The product Sucrets was introduced inBaltimore, Maryland,bySharp & Dohmein 1932.[3]

In 1966 theFederal Trade CommissionorderedMerck and Companyto discontinue thefalse claimsof germ-killing and pain-relieving properties for its Sucrets and Children's Sucrets throat lozenges.[4]In 1977, it was acquired byBeecham,later merging withSmithKline Beckmanin 1989 to form SmithKline Beecham. By 1994 the brand switched from a metal container to aplastic container.[3] SmithKline Beecham, after announcing a merger with GlaxoWellcome to formGlaxoSmithKline,sold the brand in 2000 toInsight Pharmaceuticals.In 2011, Sucrets reintroduced their product back into the familiar tin due to popular demand and nostalgia.

See also

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References

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  1. ^Janice Jorgensen (1994)."Sucrets".Encyclopedia of Consumer Brands: Personal products.St. James Press.ISBN9781558623378.Retrieved2011-09-24.
  2. ^Gargiulo AV, Burns GM, Huck CP (1992). "Dyclonine hydrochloride--a topical agent for managing pain".Illinois Dental Journal.61(4): 303–4.PMID1286862.
  3. ^ab"The Sucrets tin joins the age of plastics".USA Today.July 19, 1994. Archived fromthe originalon 2017-08-22.Retrieved2011-09-24.
  4. ^"F.T.C. Bids Merck Halt Claims That Lozenges Will Kill Germs".The New York Times.Associated Press.April 19, 1966.Retrieved2011-09-24.
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