TAS2R41

TAS2R41
Identifiers
Aliases	TAS2R41,T2R41, T2R59, taste 2 receptor member 41
External IDs	OMIM:613965;MGI:2681273;HomoloGene:16412;GeneCards:TAS2R41;OMA:TAS2R41 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	143,478,796bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	42,412,398bp
RNA expressionpattern
	Top expressed in
	muscle of thigh;
	Top expressed in
	embryo;
	More reference expression data
	n/a
Gene ontology
Molecular function	G protein-coupled receptor activity; signal transducer activity; bitter taste receptor activity;
Cellular component	integral component of membrane; plasma membrane; membrane;
Biological process	detection of chemical stimulus involved in sensory perception of bitter taste; signal transduction; response to stimulus; sensory perception of taste; G protein-coupled receptor signaling pathway;
	Sources:Amigo/QuickGO
Orthologs
	259287
	387353
	ENSG00000221855; ENSG00000284982
	ENSMUSG00000048284
	P59536
	P59532
	NM_176883
	NM_207028
	NP_795364
	NP_996911
	Wikidata
View/Edit Human	View/Edit Mouse

Taste receptor type 2 member 41is aproteinthat in humans is encoded by theTAS2R41gene.^[5]^[6]

References[edit]

^^a ^b ^cENSG00000284982 GRCh38: Ensembl release 89: ENSG00000221855, ENSG00000284982–Ensembl,May 2017
^^a ^b ^cGRCm38: Ensembl release 89: ENSMUSG00000048284–Ensembl,May 2017
^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
^Bufe B, Hofmann T, Krautwurst D, Raguse JD, Meyerhof W (Oct 2002). "The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides".Nat Genet.32(3): 397–401.doi:10.1038/ng1014.PMID 12379855.S2CID 20426192.
^"Entrez Gene: TAS2R41 taste receptor, type 2, member 41".

Margolskee RF (2002)."Molecular mechanisms of bitter and sweet taste transduction".J. Biol. Chem.277(1): 1–4.doi:10.1074/jbc.R100054200.PMID 11696554.
Montmayeur JP, Matsunami H (2002). "Receptors for bitter and sweet taste".Curr. Opin. Neurobiol.12(4): 366–71.doi:10.1016/S0959-4388(02)00345-8.PMID 12139982.S2CID 37807140.
Zhang Y, Hoon MA, Chandrashekar J, Mueller KL, Cook B, Wu D, Zuker CS, Ryba NJ (2003)."Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways".Cell.112(3): 293–301.doi:10.1016/S0092-8674(03)00071-0.PMID 12581520.S2CID 718601.
Conte C, Ebeling M, Marcuz A, Nef P, Andres-Barquin PJ (2003). "Identification and characterization of human taste receptor genes belonging to the TAS2R family".Cytogenet. Genome Res.98(1): 45–53.doi:10.1159/000068546.PMID 12584440.S2CID 1542970.
Fischer A, Gilad Y, Man O, Pääbo S (2005)."Evolution of bitter taste receptors in humans and apes".Mol. Biol. Evol.22(3): 432–6.doi:10.1093/molbev/msi027.PMID 15496549.
Go Y, Satta Y, Takenaka O, Takahata N (2006)."Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates".Genetics.170(1): 313–26.doi:10.1534/genetics.104.037523.PMC1449719.PMID 15744053.

This article incorporates text from theUnited States National Library of Medicine,which is in thepublic domain.

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