Valofane
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Chemical compound
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Other names | N-carbamoyl-5-methyl-2-oxo-3-prop-2-enyloxolane-3-carboxamide |
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ECHA InfoCard | 100.019.871![]() |
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Formula | C10H14N2O4 |
Molar mass | 226.232g·mol−1 |
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Valofaneis asedativedrug structurally related to thebarbiturates[1]and similar drugs such asprimidone.It is metabolized once inside the body to form the barbiturateproxibarbital(proxibarbal) and is thus aprodrug.[2]
References[edit]
- ^Traversa U, Puppini P, Jacquot C, Vertua R (1985). "Effect of an atypical barbiturate, the 2-allophanyl-2-allyl-4-valerolactone (valofan), on exploratory behaviour and brain serotonin concentrations in mice".Journal de Pharmacologie.16(3): 279–90.PMID2415778.
- ^Lambrey B, Compagnon PL, Jacquot C (1981). "Pharmacokinetics of 14C-2-allophanyl-2-allyl -gamma-valero-lactone: a prodrug of proxibarbal in rats".European Journal of Drug Metabolism and Pharmacokinetics.6(3): 161–9.doi:10.1007/BF03189485.PMID6118275.S2CID10197120.
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