Balofloxacin
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| Formula | C20H24FN3O4 |
| Molar mass | 389.427g·mol−1 |
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Balofloxacin(INN) is afluoroquinoloneantibiotic.It is sold under the brand nameQ-RoxininKorea,and under various names in India.[1]It is not approved by the FDA for use in the United States.
Pharmacodynamics
[edit]Balofloxacin is afluoroquinolonethat has a broad spectrum in vitro activity against a wide range ofGram-positiveandGram-negativebacteria, with enhanced activity against Gram positive bacteria, including MRSA and Streptococcus pneumoniae.[2]It functions by inhibiting the action of DNA-gyrase, preventing bacterial cells from reproducing or repairing themselves, resulting in cellular death.[3]
Side Effects
[edit]Vomiting, headache, dizziness, stomach pain, nausea, diarrhea and decreased liver function are the most common side effects. In rare cases, Balofloxacin can lead to or worsen tendinitis,[3]and muscular damage.[3]
See also
[edit]References
[edit]- ^Alksne L (February 2003). "Balofloxacin Choongwae".Current Opinion in Investigational Drugs.4(2): 224–9.PMID12669387.
- ^"NCATS Inxight Drugs — BALOFLOXACIN".drugs.ncats.io.Retrieved2022-07-28.
- ^abc"BALOFLOXACINhome: Uses, Side Effects and Medicines | Apollo Pharmacy".apollopharmacy.in.Retrieved2022-07-28.
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