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Befloxatone

From Wikipedia, the free encyclopedia
Befloxatone
Names
Preferred IUPAC name
(5R)-5-(Methoxymethyl)-3-{4-[(3R)-4,4,4-trifluoro-3-hydroxybutoxy]phenyl}-1,3-oxazolidin-2-one
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
KEGG
UNII
  • InChI=1S/C15H18F3NO5/c1-22-9-12-8-19(14(21)24-12)10-2-4-11(5-3-10)23-7-6-13(20)15(16,17)18/h2-5,12-13,20H,6-9H2,1H3/t12-,13-/m1/s1checkY
    Key: IALVDLPLCLFBCF-CHWSQXEVSA-NcheckY
  • InChI=1/C15H18F3NO5/c1-22-9-12-8-19(14(21)24-12)10-2-4-11(5-3-10)23-7-6-13(20)15(16,17)18/h2-5,12-13,20H,6-9H2,1H3/t12-,13-/m1/s1
    Key: IALVDLPLCLFBCF-CHWSQXEVBB
  • O=C2O[C@H](CN2c1ccc(OCC[C@@H](O)C(F)(F)F)cc1)COC
Properties
C15H18F3NO5
Molar mass 349.30233
Except where otherwise noted, data are given for materials in theirstandard state(at 25 °C [77 °F], 100 kPa).

Befloxatone(MD-370,503) is areversible inhibitor of monoamine oxidase A.[1][2]

References

[edit]
  1. ^Emilien, G (March 1999). "Befloxatone (Synthelabo)".IDrugs.2(3): 247–253.PMID16160936.
  2. ^Warot, Dominique; Berlin, Ivan; Patat, Alain; Durrieu, Geneviève; Zieleniuk, Isabelle; Puech, Alain J (October 1996). "Effects of Befloxatone, a Reversible Selective Monoamine Oxidase-A Inhibitor, on Psychomotor Function and Memory in Healthy Subjects".The Journal of Clinical Pharmacology.1552-4604.36(10): 942–950.doi:10.1002/j.1552-4604.1996.tb04762.x.PMID8930782.S2CID36177710.