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Dipeptidase 3

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(Redirected fromDPEP3)
DPEP3
Identifiers
AliasesDPEP3,MBD3, dipeptidase 3
External IDsOMIM:609926;MGI:1919104;HomoloGene:23357;GeneCards:DPEP3;OMA:DPEP3 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_022357
NM_001129758
NM_001370198

NM_027960

RefSeq (protein)

NP_001123230
NP_001357127

NP_082236

Location (UCSC)Chr 16: 67.98 – 67.98 MbChr 8: 106.7 – 106.71 Mb
PubMedsearch[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Dipeptidase 3(DPEP3) is aproteinthat in humans is encoded by theDPEP3gene.[5]

This gene encodes a membrane-bound glycoprotein from the family ofdipeptidases(EC 3.4.13.19) involved in hydrolytic metabolism of variousdipeptides,includingpenemandcarbapenembeta-lactamantibiotics. This gene is located on chromosome 16 in a cluster with another member of this family,DPEP2.Alternatively spliced transcript variants that encode different isoforms have been found for this gene.[6]

References

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  1. ^abcGRCh38: Ensembl release 89: ENSG00000141096Ensembl,May 2017
  2. ^abcGRCm38: Ensembl release 89: ENSMUSG00000031898Ensembl,May 2017
  3. ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^Habib GM, Shi ZZ, Cuevas AA, Lieberman MW (July 2003)."Identification of two additional members of the membrane-bound dipeptidase family".The FASEB Journal.17(10): 1313–5.doi:10.1096/fj.02-0899fje.PMID12738806.S2CID15252871.
  6. ^"Entrez Gene: Dipeptidase 3".

Further reading

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This article incorporates text from theUnited States National Library of Medicine,which is in thepublic domain.