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Prokineticin receptor

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prokineticin receptor 1
Identifiers
SymbolPROKR1
Alt. symbolsGPR73
NCBI gene10887
HGNC4524
OMIM607122
RefSeqNM_138964
UniProtQ8TCW9
Other data
LocusChr. 2p14
Search for
StructuresSwiss-model
DomainsInterPro
prokineticin receptor 2
Identifiers
SymbolPROKR2
Alt. symbolsGPR73L1
NCBI gene128674
HGNC15836
OMIM607123
RefSeqNM_144773
UniProtQ8NFJ6
Other data
LocusChr. 20p12.3
Search for
StructuresSwiss-model
DomainsInterPro

Theprokineticin receptoris aG protein-coupled receptorwhich binds the peptide hormoneprokineticin.There are two variants each encoded by a different gene (PROKR1,PROKR2).[1]These receptors mediate gastrointestinal smooth muscle contraction andangiogenesis.

References

  1. ^Lin DC, Bullock CM, Ehlert FJ, Chen JL, Tian H, Zhou QY (2002)."Identification and molecular characterization of two closely related G protein-coupled receptors activated by prokineticins/endocrine gland vascular endothelial growth factor".J. Biol. Chem.277(22): 19276–80.doi:10.1074/jbc.M202139200.PMID11886876.