3-hydroxyindolin-2-one monooxygenase
| 3-hydroxyindolin-2-one monooxygenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.14.13.139 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDBstructures | RCSB PDBPDBePDBsum | ||||||||
| |||||||||
3-hydroxyindolin-2-one monooxygenase(EC1.14.13.139,BX4 (gene),CYP71C1 (gene)) is anenzymewithsystematic name3-hydroxyindolin-2-one,NAD(P)H:oxygen oxidoreductase (2-hydroxy-2H-1,4-benzoxazin-3(4H)-one-forming).[1][2][3]This enzymecatalysesthe followingchemical reaction
- 3-hydroxyindolin-2-one + NAD(P)H + H++ O22-hydroxy-2H-1,4-benzoxazin-3(4H)-one + NAD(P)++ H2O
3-hydroxyindolin-2-one monooxygenase is involved in the biosynthesis of protective and allelopathicbenzoxazinoidsin some plants.
References
[edit]- ^Glawischnig E, Grün S, Frey M, Gierl A (March 1999). "Cytochrome P450 monooxygenases of DIBOA biosynthesis: specificity and conservation among grasses".Phytochemistry.50(6): 925–30.Bibcode:1999PChem..50..925G.doi:10.1016/s0031-9422(98)00318-5.PMID10385992.
- ^Frey M, Chomet P, Glawischnig E, Stettner C, Grün S, Winklmair A, Eisenreich W, Bacher A, Meeley RB, Briggs SP, Simcox K, Gierl A (August 1997). "Analysis of a chemical plant defense mechanism in grasses".Science.277(5326): 696–9.doi:10.1126/science.277.5326.696.PMID9235894.
- ^Spiteller P, Glawischnig E, Gierl A, Steglich W (June 2001). "Studies on the biosynthesis of 2-hydroxy-1,4-benzoxazin-3-one (HBOA) from 3-hydroxyindolin-2-one in Zea mays".Phytochemistry.57(3): 373–6.Bibcode:2001PChem..57..373S.doi:10.1016/s0031-9422(01)00037-1.PMID11393516.
External links
[edit]- 3-hydroxyindolin-2-one+monooxygenaseat the U.S. National Library of MedicineMedical Subject Headings(MeSH)
