4-HO-DSBT

4-HO-DSBT
Identifiers
	IUPAC name 3-[2-[di(butan-2-yl)amino]ethyl]-1H-indol-4-ol;
CAS Number	127507-01-1; 4-HO-DBT:63065-89-4;
PubChemCID	21786580;
ChemSpider	10513070;
UNII	E943EL34UU; 4-HO-DBT:R3EY4G4BLQ;
CompTox Dashboard(EPA)	DTXSID001045425;
Chemical and physical data
Formula	C18H28N2O
Molar mass	288.435g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCC(C)N(CCc1c[nH]c2cccc(O)c12)C(C)CC;
	InChI InChI=1S/C18H28N2O/c1-5-13(3)20(14(4)6-2)11-10-15-12-19-16-8-7-9-17(21)18(15)16/h7-9,12-14,19,21H,5-6,10-11H2,1-4H3; Key:SMKFHUHBZWMALV-UHFFFAOYSA-N;

4-HO-DsBT(4-hydroxy-N,N-di-sec-butyltryptamine) is atryptaminederivative which acts as aserotonin receptor agonist.It was first made byAlexander Shulginand is mentioned in his book TiHKAL, but was never tested by him.^[1]However it has subsequently been testedin vitroand unlike then-butyl and isobutyl isomers which are much weaker, thes-butyl derivative retains reasonable potency, with a similar5-HT_2Areceptor affinity toMiPTbut better selectivity over the5-HT_1Aand5-HT_2Bsubtypes.^[2]

References[edit]

^4-HO-DBT TiHKAL entry
^McKenna DJ, Repke DB, Lo L, Peroutka SJ (March 1990)."Differential interactions of indolealkylamines with 5-hydroxytryptamine receptor subtypes".Neuropharmacology.29(3): 193–8.doi:10.1016/0028-3908(90)90001-8.PMID 2139186.S2CID 24188017.

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[1] 4-HO-DBT TiHKAL entry

[2] McKenna DJ, Repke DB, Lo L, Peroutka SJ (March 1990)."Differential interactions of indolealkylamines with 5-hydroxytryptamine receptor subtypes".Neuropharmacology.29(3): 193–8.doi:10.1016/0028-3908(90)90001-8.PMID 2139186.S2CID 24188017.

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