Bat1K
Bat1Kis a project to sequence thegenomesof all livingbatspecies to the level ofchromosomesand then make the data publicly available. The project began in 2017.[1]
History
[edit]Bat1K was founded in 2017. Zoologist and geneticistEmma Teelingand neurogeneticist Sonja Vernes are co-founders.[1]The Bat1K consortium includes researchers from institutions such asUniversity College Dublin,University of Bristol,Max Planck Institute of Molecular Cell Biology and Genetics,andMax Planck Institute for Psycholinguistics.Notable members includeEugene Myers,Liliana M. Dávalos,Nancy Simmons,andErich Jarvis.[2][3]As of November 2017, there were 148 members in total, consisting of bat biologists, genome technologists, conservationists, and computational scientists.[4]
Applications
[edit]Several research areas could be furthered by documenting bat genomes. These include healthy ageing, disease resistance, ecosystem function andecosystem services,sensory perception, communication, limb development, and mammal genome structure.[4]
Results
[edit]In 2020, the genomes of six species were published: thegreater horseshoe bat,Egyptian fruit bat,pale spear-nosed bat,greater mouse-eared bat,Kuhl's pipistrelle,and thevelvety free-tailed bat.These genomes were called "comparable to the best reference-quality genomes that have so far been generated for anyeukaryotewith agigabase-sized genome ".[5]In 2020, the project's stated goal was to sequence an additional 27 genomes, with a representative from eachfamily of bats,within the next year.[1]
See also
[edit]References
[edit]- ^abcPennisi, Elizabeth(22 July 2020)."How bats have outsmarted viruses—including coronaviruses—for 65 million years".Science.Retrieved4 August2020.
- ^"The genetic basis of bats' superpowers revealed".University of Bristol.29 July 2020.Retrieved4 August2020.
- ^"Genomic Basis of Bat Superpowers Could Provide New Insights into Coronavirus Resistance".Genetic Engineering & Biotechnology News.23 July 2020.Retrieved4 August2020.
- ^abTeeling, Emma C.; Vernes, Sonja C.; Dávalos, Liliana M.; Ray, David A.; Gilbert, M. Thomas P.; Myers, Eugene (2018)."Bat Biology, Genomes, and the Bat1K Project: To Generate Chromosome-Level Genomes for All Living Bat Species".Annual Review of Animal Biosciences.6:23–46.doi:10.1146/annurev-animal-022516-022811.hdl:11858/00-001M-0000-002E-5F30-4.PMID29166127.
- ^Jebb, David; Huang, Zixia; Pippel, Martin; Hughes, Graham M.; Lavrichenko, Ksenia; Devanna, Paolo; Winkler, Sylke; Jermiin, Lars S.; Skirmuntt, Emilia C.; Katzourakis, Aris; et al. (2020)."Six reference-quality genomes reveal evolution of bat adaptations".Nature.583(7817): 578–584.Bibcode:2020Natur.583..578J.doi:10.1038/s41586-020-2486-3.hdl:21.11116/0000-0006-C116-7.PMC8075899.PMID32699395.S2CID220716856.