CCT4
Appearance
T-complex protein 1 subunit deltais aproteinthat in humans is encoded by theCCT4gene.[5][6]The CCT4 protein is a component of theTRiCcomplex.
Interactions
[edit]CCT4 has been shown tointeractwithPPP4C.[7][8]
References
[edit]- ^abcGRCh38: Ensembl release 89: ENSG00000115484–Ensembl,May 2017
- ^abcGRCm38: Ensembl release 89: ENSMUSG00000007739–Ensembl,May 2017
- ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^Won KA, Schumacher RJ, Farr GW, Horwich AL, Reed SI (Dec 1998)."Maturation of human cyclin E requires the function of eukaryotic chaperonin CCT".Molecular and Cellular Biology.18(12): 7584–9.doi:10.1128/mcb.18.12.7584.PMC109339.PMID9819444.
- ^"Entrez Gene: CCT4 chaperonin containing TCP1, subunit 4 (delta)".
- ^Chen GI, Tisayakorn S, Jorgensen C, D'Ambrosio LM, Goudreault M, Gingras AC (Oct 2008)."PP4R4/KIAA1622 forms a novel stable cytosolic complex with phosphoprotein phosphatase 4".The Journal of Biological Chemistry.283(43): 29273–84.doi:10.1074/jbc.M803443200.PMC2662017.PMID18715871.
- ^Gingras AC, Caballero M, Zarske M, Sanchez A, Hazbun TR, Fields S, Sonenberg N, Hafen E, Raught B, Aebersold R (November 2005)."A novel, evolutionarily conserved protein phosphatase complex involved in cisplatin sensitivity".Molecular & Cellular Proteomics.4(11): 1725–40.doi:10.1074/mcp.M500231-MCP200.PMID16085932.S2CID7531012.
Further reading
[edit]- Kubota H, Hynes G, Carne A, Ashworth A, Willison K (Feb 1994). "Identification of six Tcp-1-related genes encoding divergent subunits of the TCP-1-containing chaperonin".Current Biology.4(2): 89–99.Bibcode:1994CBio....4...89K.doi:10.1016/S0960-9822(94)00024-2.PMID7953530.S2CID31300131.
- Wu-Baer F, Lane WS,Gaynor RB(Feb 1996)."Identification of a group of cellular cofactors that stimulate the binding of RNA polymerase II and TRP-185 to human immunodeficiency virus 1 TAR RNA".The Journal of Biological Chemistry.271(8): 4201–8.doi:10.1074/jbc.271.8.4201.PMID8626763.
- Nabetani A, Hatada I, Morisaki H, Mukai T (June 1996). "Chromosomal assignment and imprinting tests for the mouse delta subunit of the cytosolic chaperonin containing TCP-1 (Cct4) gene to proximal chromosome 11".Genomics.34(2): 246–9.doi:10.1006/geno.1996.0276.PMID8661059.
- Melki R, Batelier G, Soulié S, Williams RC (May 1997). "Cytoplasmic chaperonin containing TCP-1: structural and functional characterization".Biochemistry.36(19): 5817–26.doi:10.1021/bi962830o.PMID9153422.
- Llorca O, McCormack EA, Hynes G, Grantham J, Cordell J, Carrascosa JL, Willison KR, Fernandez JJ, Valpuesta JM (December 1999). "Eukaryotic type II chaperonin CCT interacts with actin through specific subunits".Nature.402(6762): 693–6.Bibcode:1999Natur.402..693L.doi:10.1038/45294.PMID10604479.S2CID4421057.
- Llorca O, Martín-Benito J, Gómez-Puertas P, Ritco-Vonsovici M, Willison KR, Carrascosa JL, Valpuesta JM (August 2001). "Analysis of the interaction between the eukaryotic chaperonin CCT and its substrates actin and tubulin".Journal of Structural Biology.135(2): 205–18.doi:10.1006/jsbi.2001.4359.PMID11580270.
- Parissi V, Calmels C, De Soultrait VR, Caumont A, Fournier M, Chaignepain S, Litvak S (Dec 2001)."Functional interactions of human immunodeficiency virus type 1 integrase with human and yeast HSP60".Journal of Virology.75(23): 11344–53.doi:10.1128/JVI.75.23.11344-11353.2001.PMC114720.PMID11689615.
- Gevaert K, Goethals M, Martens L, Van Damme J, Staes A, Thomas GR, Vandekerckhove J (May 2003). "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides".Nature Biotechnology.21(5): 566–9.doi:10.1038/nbt810.PMID12665801.S2CID23783563.
- Imai Y, Soda M, Murakami T, Shoji M, Abe K, Takahashi R (December 2003)."A product of the human gene adjacent to parkin is a component of Lewy bodies and suppresses Pael receptor-induced cell death".The Journal of Biological Chemistry.278(51): 51901–10.doi:10.1074/jbc.M309655200.PMID14532270.
- Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R, Yamamoto J, Sekine M, Tsuritani K, Wakaguri H, Ishii S, Sugiyama T, Saito K, Isono Y, Irie R, Kushida N, Yoneyama T, Otsuka R, Kanda K, Yokoi T, Kondo H, Wagatsuma M, Murakawa K, Ishida S, Ishibashi T, Takahashi-Fujii A, Tanase T, Nagai K, Kikuchi H, Nakai K, Isogai T, Sugano S (Jan 2006)."Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes".Genome Research.16(1): 55–65.doi:10.1101/gr.4039406.PMC1356129.PMID16344560.
- Chi A, Valencia JC, Hu ZZ, Watabe H, Yamaguchi H, Mangini NJ, Huang H, Canfield VA, Cheng KC, Yang F, Abe R, Yamagishi S, Shabanowitz J, Hearing VJ, Wu C, Appella E, Hunt DF (November 2006). "Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes".Journal of Proteome Research.5(11): 3135–44.doi:10.1021/pr060363j.PMID17081065.
External links
[edit]- HumanCCT4genome location andCCT4gene details page in theUCSC Genome Browser.