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Catheter

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Catheter
Catheter disassembled

Inmedicine,acatheter(/ˈkæθətər/[1]KA-thə-tər) is a thintubemade frommedical gradematerials serving a broad range of functions. Catheters are medical devices that can be inserted in the body to treat diseases or perform a surgical procedure. Catheters are manufactured for specific applications, such as cardiovascular, urological, gastrointestinal, neurovascular and ophthalmic procedures. The process of inserting a catheter is calledcatheterization.

In most uses, a catheter is a thin, flexible tube (softcatheter) though catheters are available in varying levels of stiffness depending on the application. A catheter left inside the body, either temporarily or permanently, may be referred to as an "indwelling catheter" (for example, aperipherally inserted central catheter). A permanently inserted catheter may be referred to as a "permcath" (originally a trademark).

Catheters can be inserted into a body cavity, duct, or vessel, brain, skin or adipose tissue. Functionally, they allow drainage, administration of fluids or gases, access by surgical instruments, and also perform a wide variety of other tasks depending on the type of catheter.[2]Special types of catheters, also called probes, are used in preclinical or clinical research for sampling of lipophilic and hydrophilic compounds,[3]protein-bound and unbound drugs,[4][5]neurotransmitters, peptides and proteins, antibodies,[6][7][8]nanoparticlesand nanocarriers, enzymes and vesicles.

Etymology[edit]

"Catheter" (fromGreekκαθετήρkathetḗr) comes from the Greek verbκαθίεμαιkathíemai,meaning "to thrust into" or "to send down" because the catheter allowed fluid to be "sent down" from the body.[9]

Uses[edit]

In-line suction catheter used in ventilator circuit for delivering air into lungs
Single-use urinary catheter, 40 cm

Placement of a catheter into a particular part of the body may allow:

History[edit]

Ancient inventors[edit]

Catheters from theRoman Empire,1st century AD

Ancient Chinese used onion stalks, the Romans, Hindus, and Greeks used tubes of wood or precious metals.[11]

The ancient Egyptians created catheters fromreeds.

Modern[edit]

The earliest invention of the flexible catheter was during the 18th century.[12]Extending his inventiveness to his family's medical problems,Benjamin Franklininvented the flexible catheter in 1752 when his brother John suffered from bladder stones. Franklin's catheter was made of metal with segments hinged together with a wire enclosed to provide rigidity during insertion.[13][14]

According to a footnote in his letter in Volume 4 of the Papers of Benjamin Franklin (1959), Franklin credits Francesco Roncelli-Pardino from 1720 as the inventor of a flexible catheter. In fact, Franklin claims the flexible catheter may have been designed even earlier.[15]

An early modern application of the catheter was employed byClaude Bernardfor the purpose of cardiac catheterization in 1844. The procedure involved entering a horse's ventricles via the jugular vein and carotid artery.[16]

In 1929,Werner Forssmanfirst performedcentral venous catheterization,[17]work which led to the development ofcardiac catherizationas a treatment, for which he,André F. CournandandDickinson W. Richardswould win theNobel Prize for Medicinein 1959.[18]Central venous catheterization allows for continuous administration of medications, fluids and blood products to a large vein, particularly in critically ill patients.[17]Cardiac catheterization is the insertion of a catheter into one of the chambers of the heart, which is used for imaging, diagnosis, and the placement of devices such as stents.[19]

David S. Sheridaninvented the modern disposable catheter in the 1940s.[20]Prior to this, some reusable catheters consisted of braided cotton tubes, which were varnished, heat-treated and polished. As these were primarily produced in France, the advent ofWorld War IIthreatened the supply chain.[21]Sheridan was dubbed the "Catheter King" byForbesmagazine in 1988. He also invented the modern "disposable" plasticendotracheal tubenow used routinely in surgery.[20]

Other reusable catheters consisted of red rubber tubes. Although sterilized prior to reuse, they still posed a high risk of infection and often led to the spread of disease.[22]: 142 

To preventclotting,catheters that are not in use may be filled withcatheter lock solution.[23]

Materials[edit]

Urinary catheters[edit]

A range ofpolymersare used for the construction of catheters, includingsilicone rubber,nylon,polyurethane,polyethylene terephthalate (PET),latex,andthermoplastic elastomers.Silicone is one of the most common implantable choice because it is inert and unreactive to body fluids and a range of medical fluids with which it might come into contact. On the other hand, the polymer is weak mechanically, and a number of serious fractures have occurred in catheters.[24][25][26]For example, silicone is used inFoley catheterswhere fractures have been reported, often requiring surgery to remove the tip left in the bladder.

There are many different types of catheters for bladder problems. A typical modernintermittent catheteris made from polyurethane and comes in different lengths and sizes for men, women and children.[citation needed]

Catheters used in interventional procedures[edit]

Depending on the mechanical characteristics required, assorted polymers and polymer-metal composites can be used to build catheters used for interventional purposes. Common materials include polyamide (nylon), polyether block amide, polyuerathane, polyethylene terephthalate, andpolyimides.These materials are often used in combination with each other and are frequently layered on top of stainless steel braiding, laser-cut stainless steel tubing, or other scaffold-like structures to impart desirable handling characteristics to the catheter, all dependent on the intended application. For example, the materials and the architectures used to manufacture vascular catheters for neurological applications might differ significantly from catheters destined for cardiovascular use.

Guiding catheters (catheters that guides angioplasty balloons and stents) is made up ofpolytetrafluoroethylene(PTFE) innermost layer which is lubricious, followed bystainless steelbraid wire outer layer which helps to provide support for the catheter and prevent kinking while travelling through blood vessels, andNylonelastomer outermost layer which provides extra support for the catheter and preserve the curvature of the catheter while passing through tortuous vessels.[27]

To enhance ease of insertion, some catheters have a lubricious surface coating to lessen friction. A lubricious coating creates a smooth, slippery film making the catheter easier to insert.

Interventional procedures[edit]

Various settings of a 6Frenchpigtail catheter with locking string, obturator (also calledstiffening cannula) and puncture needle.
A.Overview.
B.Both puncture needle and obturator engaged, allowing for direct insertion.
C.Puncture needle retracted. Obturator engaged. Used for example in steady advancement of the catheter on a guidewire.
D.Both obturator and puncture needle retracted, when the catheter is in place.
E.Locking string is pulled (bottom center) and then wrapped and attached to the superficial end of the catheter.

Diagnostic catheters[edit]

There are various catheters used inangiographyprocedures. Diagnostic catheters[27][28]direct wires through blood vessels.Radiocontrast agentis then injected through the catheter to visualise the vessels via various imaging methods such ascomputed tomography(CT),projectional radiography,andfluoroscopy.[28]Pigtail catheter is a non-selective catheter with multiple side holes that can deliver large volumes of contrast into a blood vessel for imaging purposes.[29]Cobra catheter is a selective catheter used to catheterise downgoing vessels in the abdomen. Cobra catheters move forward by pushing and are removed by pulling.[30]Sidewinder catheter is a selective catheter is used to navigate the aorta.[29]Headhunter, Newton, Simmons, Bentson, and Berenstein catheters are used to navigate the into one of the three branches of thearch of aorta.[31]Yashiro Catheter is a selective, hydrophilic catheter designed for optimal entry intoceliac trunk.[32]Whereas endothelial cell sampling through endovascular sampling with coils, stents, stent retrievers, or guidewires suffer from poor selectivity and a low or highly variable cell yield, a micro-3D-printed device adapted for endovascular techniques can harvest endothelial cells for transcriptomic analysis.[33]

Balloon catheters[edit]

There are also balloon catheters used inangioplastyprocedures such as plain balloon catheters that is useful in passing tight vessel stenosis, drug coated balloons that containspaclitaxelon the surface to prevent smooth muscle cells proliferation of the vessel walls, thus reducing the likehood of vessel blockage in the future, high pressure balloons that can open stubborn vessel stenoses in veins andarteriovenous fistula,and cutting balloon angioplasty that contains 3 to 4 small blades on its surface (endotomes) that helps to control the distribution of balloon dilatation more uniformly and cut through resistant stenosis due to fibrous scar tissue.[34]

Dialysis catheters[edit]

There is no difference in achieving adequacy of blood flow, period of catheter usage, infection, and thromboembolism risk whether the dialysis catheter has step-tip, split-tip, or symmetrical tip.[35]Palidrome catheter is superior to Permcath catheter in terms of maximum blood flow, dialysis adequacy, and annual patency rate. Similar to Permcath, Palidrome catheter has high infection andthromboembolismrate.[36]

Adverse effects[edit]

In interventional procedures, Teflon catheters (which are hydrophobic) have higher risk of thrombus formation when compared to polyurethene catheters. The longer the duration of the catheter left inside the body, the higher the risk of thrombus formation. Larger catheters increase the risk of thrombus formation around the catheter, because they can block the flow of blood.[37]

"Any foreign object in the body carries an infection risk, and a catheter can serve as a superhighway for bacteria to enter the bloodstream or body", according to Milisa Manojlovich, a professor at the University of Michigan School of Nursing.[38]

Catheters can be difficult to clean, and therefore harbor antibiotic resistant[39]or otherwise pathogenic bacteria.

See also[edit]

References[edit]

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External links[edit]