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Citiolone

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Citiolone
Clinical data
ATC code
Identifiers
  • (RS)-N-(2-Oxothiolan-3-yl)acetamide
CAS Number
PubChemCID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard(EPA)
ECHA InfoCard100.013.449Edit this at Wikidata
Chemical and physical data
FormulaC6H9NO2S
Molar mass159.20g·mol−1
  • InChI=1S/C6H9NO2S/c1-4(8)7-5-2-3-10-6(5)9/h5H,2-3H2,1H3,(H,7,8)checkY
  • Key:NRFJZTXWLKPZAV-UHFFFAOYSA-NcheckY
☒NcheckY(what is this?)(verify)

Citioloneis a drug used inlivertherapy.

It is a derivative of theamino acidcysteine.[1]Citilone has also been studied with regards tohypothermiadue to it being ahydroxylfree radical scavenger. The drug has been shown to protecthamstercells subjected to temperature conditions of 8-25 °C.[2]

References

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  1. ^de Barrio M, Tornero P, Prieto A, Sainza T, Zubeldia JM, Herrero T (1997). "Recurrent fixed drug eruption caused by citiolone".Journal of Investigational Allergology & Clinical Immunology.7(3): 193–194.PMID9252880.
  2. ^Kruuv J, Glofcheski DJ (June 1993). "Further evidence for two modes of hypothermia damage".Cryobiology.30(3): 313–321.doi:10.1006/cryo.1993.1030.PMID8370318.