Jump to content

Fenamic acid

From Wikipedia, the free encyclopedia
(Redirected fromFenamate)
Fenamic acid
Ball-and-stick model of fenamic acid
Names
Preferred IUPAC name
2-Anilinobenzoic acid
Other names
N-phenylanthranilic acid
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.001.879Edit this at Wikidata
UNII
  • InChI=1S/C13H11NO2/c15-13(16)11-8-4-5-9-12(11)14-10-6-2-1-3-7-10/h1-9,14H,(H,15,16)☒N
    Key: ZWJINEZUASEZBH-UHFFFAOYSA-N☒N
  • InChI=1/C13H11NO2/c15-13(16)11-8-4-5-9-12(11)14-10-6-2-1-3-7-10/h1-9,14H,(H,15,16)
    Key: ZWJINEZUASEZBH-UHFFFAOYAQ
  • C1=CC=C(C=C1)NC2=CC=CC=C2C(=O)O
Properties
C13H11NO2
Molar mass 213.23 g/mol
Except where otherwise noted, data are given for materials in theirstandard state(at 25 °C [77 °F], 100 kPa).

Fenamic acidis anorganic compound,which, especially in its ester form, is calledfenamate.[1]: 458 serves as a parent structure for severalnonsteroidal anti-inflammatory drugs(NSAIDs), includingmefenamic acid,tolfenamic acid,flufenamic acid,andmeclofenamic acid.These drugs are commonly referred to as "anthranilic acid derivatives" or "fenamates" because fenamic acid is a derivative ofanthranilic acid.[2]: 235 [3]: 17 [2]

Fenamic acid can be synthesized from2-chlorobenzoic acidand can be converted intoacridone.[4]

References

[edit]
  1. ^Gupta, PK. Drug NomenclatureUnited States Adopted Names. Ch 27 in Remington: The Science and Practice of Pharmacy, Vol 1. Eds. David B. Troy, Paul Beringer. Lippincott Williams & Wilkins, 2006ISBN9780781746731
  2. ^abSriram D, Yogeeswari P.Medicinal Chemistry, 2nd Edition.Pearson Education India, 2010.ISBN9788131731444
  3. ^Auburn University course material. Jack DeRuiter, Principles of Drug Action 2, Fall 2002 1:Non-Steroidal Antiinflammatory Drugs (NSAIDS)
  4. ^C. F. H. Allen, G. H. W. McKee (1939). "Acridone".Organic Syntheses.2:6.doi:10.15227/orgsyn.019.0006.
Retrieved from "https://en.wikipedia.org/w/index.php?title=Fenamic_acid&oldid=1024222231"