Probable G-protein coupled receptor 12is aproteinthat in humans is encoded by theGPR12gene.[5][6][7]
The gene product of GPR12 is anorphan receptor,meaning that its endogenousligandis currently unknown. Gene disruption of GPR12 in mice results indyslipidemiaand obesity.[8]
^Bjursell M, Gerdin AK, Jönsson M, Surve VV, Svensson L, Huang XF, et al. (September 2006). "G protein-coupled receptor 12 deficiency results in dyslipidemia and obesity in mice".Biochemical and Biophysical Research Communications.348(2): 359–66.doi:10.1016/j.bbrc.2006.07.090.PMID16887097.