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Guanoxan

From Wikipedia, the free encyclopedia
Guanoxan
Clinical data
ATC code
Identifiers
  • 2-(2,3-Dihydro-1,4-benzodioxin-2-ylmethyl)guanidine
CAS Number
PubChemCID
ChemSpider
UNII
CompTox Dashboard(EPA)
Chemical and physical data
FormulaC10H13N3O2
Molar mass207.233g·mol−1
3D model (JSmol)
  • c1ccc2c(c1)OCC(O2)CNC(=N)N
  • InChI=1S/C10H13N3O2/c11-10(12)13-5-7-6-14-8-3-1-2-4-9(8)15-7/h1-4,7H,5-6H2,(H4,11,12,13)☒N
  • Key:HIUVKVDQFXDZHU-UHFFFAOYSA-N☒N
☒NcheckY(what is this?)(verify)

Guanoxanis asympatholyticdrug that was marketed asEnvacarby Pfizer in the UK to treathigh blood pressure.It was not widely used and was eventually withdrawn from the market due to liver toxicity.[1][2]

References

[edit]
  1. ^Broadley KJ (1996).Autonomic Pharmacology.CRC Press. p. 276.ISBN9780748405565.
  2. ^Wardell WM, Lasagna L (1975).Regulation and drug development.Washington: American Enterprise Institute for Public Policy Research. p.65.ISBN9780844731674.