Keith E. Mostov
Keith E. Mostovis an American cell biologist. He received a BA fromUniversity of Chicagoin 1976 and during 1976–77 he was aRhodes ScholaratNew College, Oxford.[1]Mostov received aPhDinBiological Sciencefrom theRockefeller Universityin the laboratory of Nobel laureateGünter Blobelin 1983, and anMDfromWeill Cornell Medicinein 1984. He was a Whitehead Fellow[2]at theWhitehead Instituteof MIT from 1984 to 1989. In 1989, Mostov joined the faculty of theUniversity of California, San Francisco, School of Medicine,where he is currently Professor.[3]Mostov and colleagues discovered and sequenced thePolymeric Immunoglobulin Receptor(pIgR) and proposed the generally accepted model of its pathway and function.[4]Neil E. Simister and Mostov cloned and sequenced the Neonatal Fc Receptor (FcRn).[5]Mostov and colleagues showed how signals in the pIgR direct its polarized trafficking and how polarizedMDCKepithelial cells form three-dimensional structures with lumens and tubules.[4]Mostov and colleagues further found how simple rules cause different branching patterns in kidney as compared to other branching tubular organs[6]
Honors and awards
[edit]- Rhodes Scholar[1]
- Searle Scholar[7]
- Charles E. Culpeper Foundation Medical Scholar[8]
- Mallinckrodt Foundation Scholar[9]
- NIH NIAID MERIT Award[3]
- American Society for Cell Biology ASCB Fellow[10]
References
[edit]- ^abBurks, Edward C. (1976-09-30)."Rhodes Scholars —From a Playwright to a Soldier— Sail for England".The New York Times.ISSN0362-4331.Retrieved2022-01-12.
- ^"Whitehead Institute of MIT".Whitehead Institute of MIT.Retrieved2022-01-12.
- ^ab"Keith Mostov, MD, PhD".UCSF Helen Diller Family Comprehensive Cancer Center.Retrieved2022-01-12.
- ^abApodaca, Gerard; Gallo, Luciana I.; Bryant, David M. (December 2012)."Role of membrane traffic in the generation of epithelial cell asymmetry".Nature Cell Biology.14(12): 1235–1243.doi:10.1038/ncb2635.ISSN1476-4679.PMC3771702.PMID23196841.
- ^Parham, Peter (January 1989)."MHC meets mother's milk".Nature.337(6203): 118–119.Bibcode:1989Natur.337..118P.doi:10.1038/337118a0.ISSN1476-4687.PMID2911346.S2CID37118328.
- ^Yu, Wei; Marshall, Wallace F.; Metzger, Ross J.; Brakeman, Paul R.; Morsut, Leonardo; Lim, Wendell; Mostov, Keith E. (2019-09-25)."Simple Rules Determine Distinct Patterns of Branching Morphogenesis".Cell Systems.9(3): 221–227.doi:10.1016/j.cels.2019.08.001.ISSN2405-4712.PMC7577355.PMID31557453.S2CID203569240.
- ^"Keith E. Mostov".Searle Scholars Program.Retrieved2022-01-12.
- ^"mostov / Collections: Charles E. Culpeper Foundation, Inc. records, 1866-2001 - Blacklight Search Results".empireadc.org.Retrieved2022-01-13.
- ^"Keith Mostov, MD, PhD".UCSF Helen Diller Family Comprehensive Cancer Center.Retrieved2022-01-12.
- ^"ASCB Fellows".ASCB.Retrieved2022-01-12.
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