MCOLN2
Appearance
Mucolipin-2also known asTRPML2(transient receptor potential cation channel, mucolipin subfamily, member 2) is aproteinthat in humans is encoded by theMCOLN2gene.[5]It is a member of the small family of theTRPMLchannels, a subgroup of the large protein family ofTRPion channels.
TRPML2 is associated with theArf6-regulated trafficking pathway and is involved in the intracellular transport of membranes and membrane proteins.[6]
See also
[edit]- transient receptor potential cation channel, mucolipin subfamily, member 1 (MCOLN1)
- transient receptor potential cation channel, mucolipin subfamily, member 3 (MCOLN3)
- TRPML
References
[edit]- ^abcGRCh38: Ensembl release 89: ENSG00000153898–Ensembl,May 2017
- ^abcGRCm38: Ensembl release 89: ENSMUSG00000011008–Ensembl,May 2017
- ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^Clapham DE, Julius D, Montell C, Schultz G (December 2005). "International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels".Pharmacol. Rev.57(4): 427–50.doi:10.1124/pr.57.4.6.PMID16382100.S2CID17936350.
- ^Karacsonyi C, Miguel AS, Puertollano R (October 2007)."Mucolipin-2 localizes to the Arf6-associated pathway and regulates recycling of GPI-APs".Traffic.8(10): 1404–14.doi:10.1111/j.1600-0854.2007.00619.x.PMID17662026.S2CID25624298.
External links
[edit]- MCOLN2+protein,+humanat the U.S. National Library of MedicineMedical Subject Headings(MeSH)