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Obovatol

From Wikipedia, the free encyclopedia
Obovatol
Names
Preferred IUPAC name
5-(Prop-2-en-1-yl)-3-[4-(prop-2-en-1-yl)phenoxy]benzene-1,2-diol
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
  • InChI=1S/C18H18O3/c1-3-5-13-7-9-15(10-8-13)21-17-12-14(6-4-2)11-16(19)18(17)20/h3-4,7-12,19-20H,1-2,5-6H2
    Key: OPGPFZQBCIAFLI-UHFFFAOYSA-N
  • C=CCC1=CC=C(C=C1)OC2=CC(=CC(=C2O)O)CC=C
Properties
C18H18O3
Molar mass 282.339g·mol−1
Except where otherwise noted, data are given for materials in theirstandard state(at 25 °C [77 °F], 100 kPa).

Obovatolis a biphenolicanti-inflammatory,anxiolytic,andnootropicisolated from the barkofMagnolia obovata.[1]It is a biphenyllignan.[2]

References

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  1. ^Choi, DY; Lee, JW; Peng, J; Lee, YJ; Han, JY; Lee, YH; Choi, IS; Han, SB; Jung, JK; Lee, WS; Lee, SH; Kwon, BM; Oh, KW; Hong, JT (2012)."Obovatol improves cognitive functions in animal models for Alzheimer's disease".Journal of Neurochemistry.120(6): 1048–59.doi:10.1111/j.1471-4159.2011.07642.x.PMID22212065.S2CID25896721.
  2. ^Obovatol andobovatal,novel biphenyl ether lignans from the leaves ofMagnolia obovataThunb. K Ito, T Iida, K Ichino, M Tsunezuka and M Hattori,… and Pharmaceutical Bulletin, 1982