Profen (drug class)
(Redirected fromProfens)
Left: general chemical structure of profens (Ar =aryl group). Right: chemical structure ofibuprofen
Theprofensare a class ofnonsteroidal anti-inflammatory drugs.[1]Profens are also known as2-arylpropionic acidsto reflect their chemical structure.[2]The most common example of a profen isibuprofen,which has been sold under the brand name Profen among others.
Other drugs in the class include:
- Alminoprofen
- Benoxaprofen
- Carprofen
- Dexibuprofen
- Dexketoprofen
- Fenoprofen
- Flunoxaprofen
- Flurbiprofen
- Indoprofen
- Ketoprofen
- Loxoprofen
- Miroprofen
- Naproxen
- Pelubiprofen
- Pirprofen
- Pranoprofen
- Suprofen
- Tarenflurbil
- Tiaprofenic acid
- Vedaprofen
- Zaltoprofen
References
[edit]- ^Evans, A. M. (1996). "Pharmacodynamics and pharmacokinetics of the profens: Enantioselectivity, clinical implications, and special reference to S(+)-ibuprofen".Journal of Clinical Pharmacology.36(12 Suppl): 7S–15S.doi:10.1002/j.1552-4604.1996.tb00003.x.PMID9013378.S2CID26944804.
- ^Landoni, M.; Soraci, A. (2001). "Pharmacology of Chiral Compounds 2-Arylpropionic Acid Derivatives".Current Drug Metabolism.2:37–51.doi:10.2174/1389200013338810.PMID11465150.
| pyrazolones/ pyrazolidines | |
|---|---|
| salicylates | |
| acetic acidderivatives and related substances | |
| oxicams | |
| propionic acid derivatives (profens) |
|
| n-arylanthranilic acids (fenamates) | |
| COX-2 inhibitors (coxibs) | |
| other | |
| NSAID combinations | |
Key:underlineindicates initially developed first-in-class compound of specific group;#WHO-Essential Medicines;†withdrawn drugs;‡veterinary use. | |
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