Proxibarbital
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Chemical compound
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Other names | Proxibarbital, Centralgol, Ipronal, 5-Allyl-5-(β-hydroxypropyl)barbituric acid |
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ECHA InfoCard | 100.018.004 |
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Formula | C10H14N2O4 |
Molar mass | 226.232g·mol−1 |
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Proxibarbital(Ipronal) is abarbituratederivative synthesized in 1956. It has anti-anxiety properties and is, in contrast to most barbiturates, almost without hypnotic action.[1]
It was also used in the treatment ofmigraineheadaches in a similar manner tobutalbital.[2]
Valofaneisomerises to Proxibarbal in vivo.
References
[edit]- ^Zajdel P, Kulig K, Zejc A (2008). Zejc A, Gorczyca M (eds.).Chemia leków, podręcznik dla studentów farmacji i farmaceutów[Drug chemistry, textbook for pharmacy students and pharmacists] (in Polish). Warszawa, Poland.ISBN978-83-200-3652-7.
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:CS1 maint: location missing publisher (link) - ^Sulman FG, Pfeifer Y, Tal E (December 1976). "[Migraine therapy by enzyme induction with proxibarbital]".Therapie der Gegenwart(in German).115(12): 2088–103.PMID14412.
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