Registry of Toxic Effects of Chemical Substances
 | This articleneeds additional citations forverification.(June 2015) |
Registry of Toxic Effects of Chemical Substances(RTECS) is adatabaseoftoxicityinformation compiled from the open scientific literature without reference to the validity or usefulness of the studies reported. Until 2001 it was maintained byUSNational Institute for Occupational Safety and Health(NIOSH) as a freely available publication. It is now maintained by the private companyBIOVIA[1]or from several value-added resellers and is available only for a fee or by subscription.
Contents
[edit]Six types of toxicity data are included in the file:
- Primaryirritation
- Mutageniceffects
- Reproductiveeffects
- Tumorigeniceffects
- Acute toxicity
- Other multiple dose toxicity
Specific numeric toxicity values such asLD50,LC50,TDLo,andTCLoare noted as well asspeciesstudied and the route of administration used. For all data the bibliographic source is listed. The studies are not evaluated in any way.
History
[edit]RTECS was an activity mandated by theUS Congress,established by Section 20(a)(6) of theOccupational Safety and Health Actof 1970 (PL 91-596).[2]The original edition, known as theToxic Substances Listwas published on June 28, 1971, and included toxicological data for approximately 5,000chemicals.The name changed later to its current nameRegistry of Toxic Effects of Chemical Substances.In January 2001 the database contained 152,970 chemicals. In December 2001 RTECS was transferred from NIOSH to the private companyElsevier MDL.Symyx acquired MDL from Elsevier in 2007 and the Toxicity database was included in the acquisition. The Toxicity database is only accessible for charge on an annual subscription base.
RTECS is available in English, French and Spanish language versions, offered by theCanadian Centre for Occupational Health and Safety.The database subscription is offered on the Web, on CD-ROM and as an Intranet format. The database is also available online from NISC (National Information Services Corporation, RightAnswer, andToxPlanet(Timberlake Ventures, Inc)).
References
[edit]- ^"BIOVIA Databases | Bioactivity Databases: RTECS".accelrys.Archived fromthe originalon 2018-06-19.Retrieved2018-06-19.
- ^Development, Office of Research &."REGISTRY OF TOXIC EFFECTS OF CHEMICAL SUBSTANCES (RTECS)".cfpub.epa.gov.Retrieved2023-08-13.
External links
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