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Roel Nusse

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Roeland "Roel" Nusse
Born(1950-06-09)9 June 1950(age 74)
Alma materUniversity of Amsterdam,University of California, San Francisco
Scientific career
InstitutionsStanford University
Academic advisorsHarold Varmus

Roeland "Roel" Nusse(born 9 June 1950,Amsterdam) is a professor atStanford Universityand an investigator at theHoward Hughes Medical Institute.[1]His research was seminal in the discovery ofWnt signaling,a family of pleiotropic regulators involved in development and disease.[2]

Research[edit]

Nusse received his BSc in biology and hisPhDfrom theUniversity of Amsterdam.Nusse did a postdoctoral fellowship under the guidance ofHarold Varmusat theUniversity of California, San Francisco.In 1982, Nusse and Varmus discovered theWnt1gene.[3]

After his postdoctoral fellowship, Nusse joined the Netherlands Cancer Institute expanding on the earlier work on the Wnt pathway and identifying the pathway in fruit flies. In 1990, he joined the department ofDevelopmental BiologyatStanford University.His lab is currently focused on the role of Wnt in stem cell development and tissue repair.

Awards[edit]

Nusse received thePeter DebyePrize from theUniversity of Maastrichtin 2000. He is a member of theU.S. National Academy of Sciences,European Molecular Biology Organization,and theRoyal Netherlands Academy of Arts and Sciences(since 1997).[4]He is a fellow of theAmerican Academy of Arts and Sciences.[1]He won aBreakthrough Prizein 2017.[5]In 2020 he received theCanada Gairdner International Award.[6]

References[edit]

  1. ^ab"Roel Nusse".HHMI.Retrieved6 September2013.
  2. ^Nusse, Roel; Varmus, Harold (22 May 2012)."Three decades of Wnts: a personal perspective on how a scientific field developed".The EMBO Journal.31(12): 2670–2684.doi:10.1038/emboj.2012.146.PMC3380217.PMID22617420.
  3. ^Nusse, R; Varmus, HE (November 1982). "Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome".Cell.31(1): 99–109.doi:10.1016/0092-8674(82)90409-3.PMID6297757.S2CID46024617.
  4. ^"Roel Nusse".Royal Netherlands Academy of Arts and Sciences. Archived fromthe originalon 17 July 2015.
  5. ^"5 top scientists win Breakthrough Prizes in star-studded event".5 December 2016.
  6. ^"Gairdner Awards 2020 Laureates".Retrieved14 December2021.

External links[edit]