SOCS7
Suppressor of cytokine signaling 7is aproteinthat in humans is encoded by theSOCS7gene.[5][6][7]
Interactions
[edit]SOCS7 has been shown tointeractwithNCK1.[5]
References
[edit]- ^abcENSG00000274211 GRCh38: Ensembl release 89: ENSG00000274229, ENSG00000274211–Ensembl,May 2017
- ^abcGRCm38: Ensembl release 89: ENSMUSG00000038485–Ensembl,May 2017
- ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^abMatuoka K, Miki H, Takahashi K, Takenawa T (Oct 1997). "A novel ligand for an SH3 domain of the adaptor protein Nck bears an SH2 domain and nuclear signaling motifs".Biochemical and Biophysical Research Communications.239(2): 488–92.doi:10.1006/bbrc.1997.7492.PMID9344857.
- ^Kile BT, Schulman BA, Alexander WS, Nicola NA, Martin HM, Hilton DJ (May 2002). "The SOCS box: a tale of destruction and degradation".Trends in Biochemical Sciences.27(5): 235–41.doi:10.1016/S0968-0004(02)02085-6.PMID12076535.
- ^"Entrez Gene: SOCS7 suppressor of cytokine signaling 7".
Further reading
[edit]- Cooney RN (Feb 2002)."Suppressors of cytokine signaling (SOCS): inhibitors of the JAK/STAT pathway".Shock.17(2): 83–90.doi:10.1097/00024382-200202000-00001.PMID11837794.S2CID40940132.
- Wormald S, Hilton DJ (Jan 2004)."Inhibitors of cytokine signal transduction"(PDF).The Journal of Biological Chemistry.279(2): 821–4.doi:10.1074/jbc.R300030200.PMID14607831.S2CID3469978.
- Fujimoto M, Naka T (Dec 2003). "Regulation of cytokine signaling by SOCS family molecules".Trends in Immunology.24(12): 659–66.doi:10.1016/j.it.2003.10.008.PMID14644140.
- Hilton DJ, Richardson RT, Alexander WS, Viney EM, Willson TA, Sprigg NS, Starr R, Nicholson SE, Metcalf D, Nicola NA (Jan 1998)."Twenty proteins containing a C-terminal SOCS box form five structural classes".Proceedings of the National Academy of Sciences of the United States of America.95(1): 114–9.Bibcode:1998PNAS...95..114H.doi:10.1073/pnas.95.1.114.PMC18144.PMID9419338.
- Dogusan Z, Hooghe-Peters EL, Berus D, Velkeniers B, Hooghe R (Sep 2000). "Expression of SOCS genes in normal and leukemic human leukocytes stimulated by prolactin, growth hormone and cytokines".Journal of Neuroimmunology.109(1): 34–9.doi:10.1016/S0165-5728(00)00300-3.PMID10969179.S2CID23752435.
- Krebs DL, Uren RT, Metcalf D, Rakar S, Zhang JG, Starr R, De Souza DP, Hanzinikolas K, Eyles J, Connolly LM, Simpson RJ, Nicola NA, Nicholson SE, Baca M, Hilton DJ, Alexander WS (Jul 2002)."SOCS-6 binds to insulin receptor substrate 4, and mice lacking the SOCS-6 gene exhibit mild growth retardation".Molecular and Cellular Biology.22(13): 4567–78.doi:10.1128/MCB.22.13.4567-4578.2002.PMC133908.PMID12052866.
- Martens N, Wery M, Wang P, Braet F, Gertler A, Hooghe R, Vandenhaute J, Hooghe-Peters EL (Aug 2004). "The suppressor of cytokine signaling (SOCS)-7 interacts with the actin cytoskeleton through vinexin".Experimental Cell Research.298(1): 239–48.doi:10.1016/j.yexcr.2004.04.002.PMID15242778.
- Martens N, Uzan G, Wery M, Hooghe R, Hooghe-Peters EL, Gertler A (Apr 2005)."Suppressor of cytokine signaling 7 inhibits prolactin, growth hormone, and leptin signaling by interacting with STAT5 or STAT3 and attenuating their nuclear translocation".The Journal of Biological Chemistry.280(14): 13817–23.doi:10.1074/jbc.M411596200.PMID15677474.
- Banks AS, Li J, McKeag L, Hribal ML, Kashiwada M, Accili D, Rothman PB (Sep 2005)."Deletion of SOCS7 leads to enhanced insulin action and enlarged islets of Langerhans".The Journal of Clinical Investigation.115(9): 2462–71.doi:10.1172/JCI23853.PMC1190369.PMID16127460.
- Kremer BE, Adang LA, Macara IG (Sep 2007)."Septins regulate actin organization and cell-cycle arrest through nuclear accumulation of NCK mediated by SOCS7".Cell.130(5): 837–50.doi:10.1016/j.cell.2007.06.053.PMC2085444.PMID17803907.
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