Schradan
Appearance
![]() | |
Names | |
---|---|
Preferred IUPAC name
Octamethyldiphosphoric tetraamide | |
Other names
OMPA, Octamethyl pyrophosphoramide
| |
Identifiers | |
3D model (JSmol)
|
|
ChEBI | |
ChemSpider | |
ECHA InfoCard | 100.005.275 |
EC Number |
|
KEGG | |
PubChemCID
|
|
RTECS number |
|
UNII | |
UN number | 3018 |
CompTox Dashboard(EPA)
|
|
| |
| |
Properties | |
C8H24N4O3P2 | |
Molar mass | 286.253g·mol−1 |
Density | 1.09 |
Hazards | |
Occupational safety and health(OHS/OSH): | |
Main hazards
|
Toxic |
GHSlabelling: | |
![]() ![]() | |
Danger | |
H300,H310,H330,H371,H373,H412 | |
P260,P262,P264,P270,P271,P273,P280,P284,P301+P310,P302+P350,P304+P340,P309+P311,P310,P314,P320,P321,P322,P330,P361,P363,P403+P233,P405,P501 | |
Except where otherwise noted, data are given for materials in theirstandard state(at 25 °C [77 °F], 100 kPa).
|
Schradan,named afterGerhard Schrader,is an obsoleteorganophosphate insecticide.[1]Schradan itself is a weak cholinesterase inhibitor and requires metabolic activation to become active.[2]
See also
[edit]References
[edit]- ^GARDINER, JE; KILBY, BA (April 1952)."Biochemistry of organic phosphorus insecticides. I. The mammalian metabolism of bis(dimethylamino) phosphonous anhydride (Schradan)".The Biochemical Journal.51(1): 78–85.doi:10.1042/bj0510078.PMC1197790.PMID14944535.
- ^DAVISON, AN (October 1955)."The conversion of schra dan (OMPA) and parathion into inhibitors of cholinesterase by mammalian liver".The Biochemical Journal.61(2): 203–9.doi:10.1042/bj0610203.PMC1215773.PMID13260199.