Schradan
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| Names | |
|---|---|
| Preferred IUPAC name
Octamethyldiphosphoric tetraamide | |
| Other names
OMPA, Octamethyl pyrophosphoramide
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| Identifiers | |
3D model (JSmol)
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| ChEBI | |
| ChemSpider | |
| ECHA InfoCard | 100.005.275 |
| EC Number |
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| KEGG | |
PubChemCID
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| RTECS number |
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| UNII | |
| UN number | 3018 |
CompTox Dashboard(EPA)
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| Properties | |
| C8H24N4O3P2 | |
| Molar mass | 286.253g·mol−1 |
| Density | 1.09 |
| Hazards | |
| Occupational safety and health(OHS/OSH): | |
Main hazards
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Toxic |
| GHSlabelling: | |
 
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| Danger | |
| H300,H310,H330,H371,H373,H412 | |
| P260,P262,P264,P270,P271,P273,P280,P284,P301+P310,P302+P350,P304+P340,P309+P311,P310,P314,P320,P321,P322,P330,P361,P363,P403+P233,P405,P501 | |
Except where otherwise noted, data are given for materials in theirstandard state(at 25 °C [77 °F], 100 kPa).
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Schradan,named afterGerhard Schrader,is an obsoleteorganophosphate insecticide.[1]Schradan itself is a weak cholinesterase inhibitor and requires metabolic activation to become active.[2]
See also
[edit]References
[edit]- ^GARDINER, JE; KILBY, BA (April 1952)."Biochemistry of organic phosphorus insecticides. I. The mammalian metabolism of bis(dimethylamino) phosphonous anhydride (Schradan)".The Biochemical Journal.51(1): 78–85.doi:10.1042/bj0510078.PMC1197790.PMID14944535.
- ^DAVISON, AN (October 1955)."The conversion of schra dan (OMPA) and parathion into inhibitors of cholinesterase by mammalian liver".The Biochemical Journal.61(2): 203–9.doi:10.1042/bj0610203.PMC1215773.PMID13260199.
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