Small nucleolar RNA Z256
| Small nucleolar RNA Z256 | |
|---|---|
 Predictedsecondary structureandsequence conservationof snoZ256 | |
| Identifiers | |
| Symbol | snoZ256 |
| Rfam | RF00301 |
| Other data | |
| RNAtype | Gene;snRNA;snoRNA;CD-box |
| Domain(s) | Eukaryota |
| GO | GO:0006396GO:0005730 |
| SO | SO:0000593 |
| PDBstructures | PDBe |
Inmolecular biology,Small nucleolar RNA Z256is anon-coding RNA(ncRNA) molecule which functions in the modification of othersmall nuclear RNAs(snRNAs). This type of modifying RNA is usually located in thenucleolusof the eukaryotic cell which is a major site of snRNA biogenesis. It is known as asmall nucleolar RNA(snoRNA) and also often referred to as a guide RNA.
snoRNA Z256 belongs to theC/D boxclass of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylationof substrate RNAs.[1]
Plant snoRNA Z256 was identified in a screen ofOryza sativa.[2]
References
[edit]- ^Galardi, S.; Fatica, A.; Bachi, A.; Scaloni, A.; Presutti, C.; Bozzoni, I. (October 2002)."Purified Box C/D snoRNPs Are Able to Reproduce Site-Specific 2'-O-Methylation of Target RNA in Vitro".Molecular and Cellular Biology.22(19): 6663–6668.doi:10.1128/MCB.22.19.6663-6668.2002.PMC134041.PMID12215523.
- ^Chen CL, Liang D, Zhou H, Zhuo M, Chen YQ, Qu LH (2003)."The high diversity of snoRNAs in plants: identification and comparative study of 120 snoRNA genes from Oryza sativa".Nucleic Acids Res.31(10): 2601–13.doi:10.1093/nar/gkg373.PMC156054.PMID12736310.
External links
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