Talk:Gramicidin

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Incorrect picture

The picture of Gramicidin A is incorrect (2 instead of 6 H-bonds between the monomers, and so on). How it has been generated? It should be replaced.Biophys 03:35, 31 October 2006 (UTC)[reply]

It was created in ChemDraw. If you're so inclined to make another one, be my guest. But it depicts the motif quite well, IMHOJgassens 21:17, 14 July 2007 (UTC)[reply]

Well, the numbers of hydrogen bonds between the monomer and within each monomer are wrong (actually, there are more H-bonds). Do we need this picture when someone inserted a better and rotating one?Biophys 01:57, 5 September 2007 (UTC)[reply]

I don't see why the picture has to rotate. And I don't know if it's a very good picture. Why is the molecule several times in there? This is just an artefact of the structure determination but it has no meaning for someone who tries to understand the structure. And why do you need to show the uncertainties?FelixP 16:58, 1 November 2007 (UTC)[reply]

IT SHOULD BE 'CELL MEMBRANE'

The first line of para "Pharmacological effects" reads: 'Gramicidin's bactericidal activity is a result of increasing the permeability of the bacterial cell wall allowing inorganic monovalent cations' Is it cell wall or cell membrane? I think it has to be cell membrane.—Precedingunsignedcomment added byHbaryan(talk•contribs)13:56, 1 April 2010 (UTC)[reply]

References

The references were moved to a separate section.Biophys 03:35, 31 October 2006 (UTC)[reply]

Assessment comment

The comment(s) below were originally left atTalk:Gramicidin/Comments,and are posted here for posterity. Followingseveral discussions in past years,these subpages are now deprecated. The comments may be irrelevant or outdated; if so, please feel free to remove this section.

There is something wrong with the statement about chloride ion(Cl-), which like most anions has very little in the way of hydration. It is the positive ions that have strong interactions with water molecules. SO this cannot be the basis of the cation selectivity. More likely is the prescence of negative charges.97.113.105.147(talk)22:13, 22 September 2009 (UTC)[reply]

Last edited at 22:13, 22 September 2009 (UTC). Substituted at 16:35, 29 April 2016 (UTC)