Theranos
![]() | |
Formerly | Real-Time Cures (2003) |
---|---|
Company type | Private |
Industry | Health care |
Founded | 2003 |
Founder | Elizabeth Holmes |
Defunct | September 2018[a] |
Fate | Dissolved andliquidated;founder convicted (January 2022) ofwire fraudandconspiracyand sentenced to11+1⁄4years (135 months) in prison |
Headquarters | , United States |
Key people |
|
Products | Blood tests |
Services | Medical tests |
Website | theranosat theWayback Machine(archived August 28, 2018) |
Footnotes / references [3][4] |
Theranos Inc.(/ˈθɛr.ən.oʊs/) was an Americanprivately heldcorporation[5]that was touted as a breakthroughhealth technologycompany. Founded in 2003 by then 19-year-oldElizabeth Holmes,Theranos raised more thanUS$700 million from venture capitalists and private investors, resulting in a $10 billion valuation at its peak in 2013 and 2014. The company claimed that it had devisedblood teststhat required very small amounts of blood and that could be performed rapidly and accurately, all using compact automated devices that the company had developed. These claims were proven to be false.[4][6][7]
A turning point came in 2015, when medical research professorJohn Ioannidis,and later professor of clinical biochemistryEleftherios Diamandis,along with investigative journalistJohn CarreyrouofThe Wall Street Journal,questioned the validity of Theranos's technology. The company faced a string of legal and commercial challenges from medical authorities, investors, theU.S. Securities and Exchange Commission(SEC), theCenters for Medicare and Medicaid Services(CMS), state attorneys general, former business partners, patients, and others.[8]By June 2016,Forbesestimated that Holmes's personal net worth had dropped from $4.5 billion to "nothing".[9]After several years of struggle, lawsuits, and sanctions from CMS, what remained of the company was dissolved in September 2018.[a]
Theranos, Holmes and former company presidentSunny Balwaniwere charged withfraudby the SEC in 2018. Holmes and Balwani were also charged withwire fraudand conspiracy, with Holmes being found guilty on four counts in January 2022 and sentenced that November to 11 years and 3 months in prison. Balwani was convicted on all 12 counts brought against him in July 2022, and in December 2022 was sentenced to 12 years and 11 months in prison and 3 years of probation.
History
[edit]While atStanford University,Elizabeth Holmeshad an idea to develop a wearable patch that could adjust the dosage of drug delivery and notify doctors of variables in patients' blood.[10]She started developinglab-on-a-chiptechnology forblood tests,with the idea to start a company that would make blood tests cheaper, more convenient and accessible to consumers.[11]Holmes dropped out of Stanford in 2003 and used the education trust from her parents to found the company that would later be called Theranos, derived from a combination of the words "therapy" and "diagnosis".[12][13][14]The company's original name was "Real-Time Cures",[15][16][17]which Holmes changed after deciding that too many people were skeptical of the word "cure".[15]
Partnerships
[edit]In 2012Safewayinvested $350 million into retrofitting 800 locations with clinics that would offer in-store blood tests. After many missed deadlines and questionable results from a trial clinic at Safeway's corporate offices, the deal was terminated in 2015.[18]In 2013, Theranos partnered withWalgreensto offer in-store blood tests at more than 40 locations.[19]Although Theranos blood tests were reportedly used on drug trial patients forGlaxoSmithKlineandPfizer,both companies stated in October 2015 that there were no active projects with Theranos.[20][21]In June 2016, Walgreens terminated its partnership with Theranos. In November 2016 it filed a suit against Theranos in federal court in Delaware for breach of contract. In June 2017, Theranos reported to investors that the suit, which originally sought $140 million in damages, was settled for less than $30 million.[22][23]
In March 2015 theCleveland Clinicannounced a partnership with Theranos to test its technology and decrease the cost of lab tests.[24][25]In July 2015, Theranos became the lab-work provider for Pennsylvania insurers AmeriHealth Caritas and Capital Blue Cross.[26][27]In July 2015 theFood and Drug Administrationapproved the use of the company's fingerstick blood testing device for theherpes simplex virus(HSV-1) outside a clinical laboratory setting.[28][29]Theranos was named the 2015 Bioscience Company of the Year by the Arizona BioIndustry Association (AzBio).[30]
Exposure and downfall
[edit]![](https://upload.wikimedia.org/wikipedia/commons/thumb/e/ea/John_Ioannidis_2015_00.21_%28crop%29.jpg/170px-John_Ioannidis_2015_00.21_%28crop%29.jpg)
In February 2015 Stanford professorJohn Ioannidiswrote in theJournal of the American Medical Associationthat no peer-reviewed research from Theranos had been published in medical research literature.[31][32]In May 2015,University of TorontoProfessorEleftherios Diamandisanalyzed Theranos technology and concluded that "most of the company's claims are exaggerated."[33][34]Attempting to boost the company's credibility, Holmes invited then-U.S. Vice PresidentJoe Bidento tour their facility. Biden praised what he saw,[35]but to conceal the lab's true operating conditions, Holmes and Balwani had created afake labfor the Vice President's tour.[36]
![](https://upload.wikimedia.org/wikipedia/commons/thumb/6/6f/John_Carreyrou_9-12-2019_DSC02013_%2848724580882%29_%28cropped%29.jpg/170px-John_Carreyrou_9-12-2019_DSC02013_%2848724580882%29_%28cropped%29.jpg)
In October 2015John CarreyrouofThe Wall Street Journalreported that Theranos was using traditional blood testing machines instead of the company'sEdison devicesto run its tests, and that the company's Edison machines might provide inaccurate results.[37][38]Tyler Shultz, a Theranos employee from 2013 to 2014 and the grandson of then-Theranos director, formerU.S. Secretary of StateGeorge P. Shultz,was a key source for theWSJstory. Shultz had attempted to take his concerns to company management. When that failed, he had spoken to Carreyrou and also, under an alias, reported the company to theNew York State Department of Healthfor CLIA violations.[39][40]
Theranos claimed that the allegations were "factually and scientifically erroneous."[41][42]Walgreens suspended plans to expand blood-testing centers in their stores following the report.[43][44]At that time, theCleveland Clinicannounced that it would work to verify Theranos technology.[25]Theranos fought back against theJournal'sinvestigation, sending lawyers after sources in the story, including Shultz, in an effort to stop them from providing information to the press.[6][39]Former employees ofreputation managementfirmStatus Labssaid that Theranos hadhired the firm to discreetly erase mentionsof theWSJ's reporting from itsWikipediaarticle, despite the activity being a violation of the website'sterms of use.[45]
Following theWSJstory, the history of FDA interactions with Theranos was scrutinized. The FDA had received a formal inquiry to look at Theranos blood test devices by theU.S. Department of Defensein 2012, before the devices were commercially available and did not require FDA approval.[46]FDA inspection reports from 2014 and 2015 stated that its containers for blood collection were "not validated under actual or simulated use conditions" and "were not reviewed and not approved by designated individual(s) prior to issuance".[47]
In 2015, an FDA inspection resulted in multiple observed violations ofFDA Title 21 Regulations.[48]It was eventually revealed that the FDA had classified Theranos's device, called a nanotainer, as aClass II medical device,meaning that Theranos would need to use special labels, meet certain performance standards and perform post-market surveillance of the device. Theranos asserted that the nanotainer was aClass I medical deviceand therefore not subject to any regulatory requirements.[49]After the 2015 inspection, Theranos announced that it would voluntarily suspend its tests apart from the FDA-approved herpes simplex virus (HSV-1) test.[50][51]
TheArizona Department of Health Servicesreported issues with the company's Scottsdale lab meeting regulations in September 2015. The reports were revealed in theArizona Republicin November 2015.[52]In January 2016 theCenters for Medicare and Medicaid Services(CMS) sent a letter to Theranos based on a 2015 inspection of itsNewark, Californialab, reporting that the facility caused "immediate jeopardyto patient health and safety "due to a test to determine the correct dose of theblood-thinning drugwarfarin.[53][54]Walgreens subsequently announced a suspension of Theranos blood tests from the Newark lab and immediately paused wellness services in Palo Alto. Theranos also agreed to stop tests at the Capital Blue Cross retail store in Enola, Pennsylvania.[55]
In the four months that followed Theranos faced further action from government agencies. CMS regulators announced plans to enact sanctions that included suspending Holmes and Balwani from owning or operating any certified clinical laboratory for two years and that they would revoke the facility's certification as a clinical laboratory.[56][57]The company came under criminal investigation by federal prosecutors and theSECfor allegedly misleading investors and government officials about its technology.[58]TheU.S. House of Representatives Committee on Energy and Commercerequested information on what Theranos was doing to correct its testing inaccuracies and adherence to federal guidelines.[59][60]In July 2016 Theranos announced that the CMS had revoked itsClinical Laboratory Improvement Amendments(CLIA) certificate and issued sanctions prohibiting its owners and operators from owning or operating a clinical laboratory for two years, suspension of approval to receive Medicare and Medicaid payments, and a civil monetary penalty. The company discontinued testing at its Newark location while attempting to resolve the issues.[61]Theranos announced plans to appeal the decision by regulators to revoke its license to operate a lab in California and other sanctions.[62]
In May 2016 Theranos announced that it had voided two years of results from its Edison device.[63]The company announced that about 1% of test results had been voided or corrected from its proprietary machines in June 2016.[64]Within two weeks, Walgreens formally terminated its partnership with Theranos and would close all remaining Theranos wellness centers.[65]In August 2016 the company withdrew its request for emergency clearance of aZika virusblood test after a lack of essential safeguards during the testing process was found by federal inspectors.[66][67]Theranos announced that it would close its laboratory operations and wellness centers and lay off about 40% of its workforce to work on miniature medical testing machines in October 2016.[68][69][70][71]In January 2017, Theranos announced that it had laid off a further 41% of its workforce, or approximately 155 people, and closed the last remaining blood-testing facility after the lab failed a second major U.S. regulatory inspection.[72][73]Also that month, the company faced lawsuits from several different entities including Walgreens[74][75]andArizona Attorney GeneralMark Brnovich.[76]
In April 2017 lawyers for Partner Investments LP and two other funds, with combined stakes totaling more than $96 million in Theranos preferred shares, charged that Theranos had threatened to seekbankruptcy protectionif the investors did not agree to accept additional stock equity in lieu of litigation. Theranos officials said the funds had mischaracterized the exchange offer, which was discussed before the suit was filed.[77]The suit also alleged that Theranos had misled company directors about its practices concerning laboratory testing and that it had secretly bought lab equipment to run fake demonstrations.[78]On May 1, 2017, Theranos announced that it had reached an undisclosed settlement with Partner Fund Management LP (PFM). Theranos'sGeneral Counsel,David Taylor, stated: "Theranos is pleased to have resolved both lawsuits with PFM. Although we are confident that we would have prevailed at trial, resolution of these two cases allows our tender offer to go forward and enables us to return our focus where it belongs, which is on executing our business plans and delivering value for our shareholders."[79]In April 2017, Theranos reached a settlement with CMS agreeing to stay out of the blood-testing business for at least two years in exchange for reduced penalties,[80]and signed aconsent decreewith Arizona Attorney GeneralMark Brnovichover violations of theArizona Consumer Fraud Act.Alleged violations includedfalse advertisementand inaccurate blood testing. Theranos agreed to refund $4.65 million to the state's residents for Theranos blood testing services, providing a refund to every resident who had received a test, regardless of whether the test results were voided or corrected.[81][82][83][84]
In August 2017 Theranos announced it had reached a settlement with Walgreens.[85]In December 2017Fortress Investment Group,a wholly owned company ofSoftbank Group,loaned $100 million to Theranos for 4% of the company.[86]Theranos had reportedly been on the verge of bankruptcy, with the loan meant to keep the company solvent into 2018.[87][88][89]The loan was secured by Theranos's patents.[90]On April 10, 2018, the company laid off the majority of workers in a renewed bid to avoid bankruptcy. The company's total headcount was fewer than 25 employees, after having 800 employees at its peak.[3][91]Softbank's Fortress bought up Theranos patents and later, taking advantage of the new market conditions in the midst of theCOVID-19 pandemic,set up a shell company called Labrador Diagnostics which sued one of the companies making COVID-19 tests, saying that its test violated those Theranos patents.[92]Theranos was still being issued patents into 2019 because of the lengthy patent application process.[93]
Shutdown
[edit]On September 4, 2018, Theranos announced in an email to investors that it would cease operations and release its assets and remaining cash to creditors after all efforts to find a buyer were fruitless. Most of the company's remaining employees had been laid off on the previous Friday, August 31. However, Theranos general counsel and new CEO David Taylor and a few support staffers remained on payroll for a few more days. Any equity investments in the company were made worthless by the shutdown.[94]Theranos would later transfer its patents to Fortress Investment Group on September 12 in exchange for Theranos' cash assets to be distributed to creditors.[2]
Civil and criminal proceedings
[edit]In March 2018 theUS Securities and Exchange Commissionfiled civil fraud charges against Theranos, its CEOElizabeth Holmesand former presidentRamesh "Sunny" Balwani,claiming they had engaged in an "elaborate, years-long fraud" wherein they "deceived investors into believing that its key product – a portable blood analyzer – could conduct comprehensive blood tests from finger drops of blood".[95][96]Holmes reached a settlement with the SEC which required her to pay $500,000, forfeit 19 million shares of company stock, and be barred from having a leadership position in any public company for ten years.[97]Balwani did not settle with the SEC.[98]
On June 15, 2018, Holmes and Balwani wereindictedon multiple counts ofwire fraudand conspiracy to commit wire fraud.[99]According to the indictment, investors, doctors and patients were defrauded. It is alleged the defendants were aware of the unreliability and inaccuracy of their products, but concealed that information. The case,United States v. Elizabeth A. Holmes, et al.,was assigned toLucy H. Koh,United States district judgeof theUnited States District Court for the Northern District of California.[100][101]The jury selection for the trial was to begin on July 28, 2020, and the trial was to have commenced in August 2020; however, theCOVID-19 pandemicled to a proposed October date,[102]before the trial for Holmes was rescheduled to begin on August 31, 2021, with Balwani's trial pushed back further to 2022.
In February 2021 federal prosecutors accused Holmes and other executives of destroying evidence in Theranos's final days in business. The specific evidence in question is the history of internal testing, including accuracy and failure rates of Theranos's blood-testing systems.[103]On January 3, 2022, Holmes was found guilty of four counts of wire fraud and one count of conspiracy to commit wire fraud.[104]She was sentenced in November 2022 to 11 years and 3 months in prison.[104][105]On May 30, 2023, Holmes began serving her sentence atFederal Prison Camp, BryaninBryan, Texas.[106]Balwani's trial began in March 2022[107]and he was convicted of 12 counts of fraud in July 2022.[108]In December he was sentenced to 12 years and 11 months in prison and 3 years of probation.[109]
Technology and products
[edit]Theranos claimed to have developed devices to automate and miniaturize blood tests using microscopic blood volumes. Theranos dubbed its blood collection vessel the "nanotainer" and its analysis machine the "Edison".[110][111][112]Holmes reportedly named the device "Edison" after inventorThomas Edison,stating, "We tried everything else and it failed, so let's call it the Edison." This was likely because of a well-known Edison quote: "I've not failed. I've just found 10,000 ways that won't work."[113]The blood sample was to be collected via a finger prick and then transferred to the nanotainer through Theranos's sample collection device. At just 12.9 millimetres (0.51 in) in height, the nanotainer held a couple of drops of blood.[113]
One of the patents for the Edison described a point of care system that could communicate with the Internet to receive instructions for which blood tests to run on the samples, before communicating these results back through the Internet. The results would then be compared to medical data available on the Internet, with the Edison running supplementary blood tests that were more targeted based on the results of the comparison. The patent was unclear on how much blood the Edison would actually require to conduct these blood tests. In one section, the patent claimed the sample needed to consist of about 10 drops of blood, but in another section, the patent claimed the Edison would need less than one drop of blood.[114]The technology was criticized for not beingpeer reviewed.[115][116]Theranos claimed to have data verifying the accuracy and reliability of its tests that would be published.[117]In February 2016, Theranos announced that it would permit the Cleveland Clinic to complete a validation study of its technology.[118]
In March 2016, a study authored by 13 scientists appeared in theJournal of Clinical Investigation,where it was stated that the company's blood test results were flagged "outside their normal range 1.6× more often than other testing services", that 68 percent of lab measurements evaluated "showed significant interservice variability", and that "lipid panel test results between Theranos and other clinical services" were "nonequivalent".[119]In August 2016 the company introduced a new robotic capillary blood testing unit named "miniLab" at the 2016 annual meeting of theAmerican Association for Clinical Chemistry,but did not present any data supporting the claimed abilities of the device.[120][121][122]The miniLab was allegedly capable of carrying out a range of tests from a small amount of blood. After Theranos failed to address concerns that it exaggerated the capabilities of the miniLab, Walgreens withdrew from their partnership. It was later revealed that Theranos had voided two years of test results showing inaccuracies with the Edison technology.[123]
Corporate affairs
[edit]Location
[edit]The company moved from 3200 Hillview Ave to the former headquarters ofFacebookat 1601 S. California Ave in June 2012.[124][125]By 2017 Theranos was headquartered at 1701 Page Mill Road, Palo Alto, California, paying a $1 million per month lease for theStanford Research Parkbuilding.[126][127]It had laboratories inNewark, California,andScottsdale, Arizona.[128]In 2017, when Theranos was still denying its publicly reported fraud, the company vacated its Page Mill headquarters, moving remaining staff into the Newark, California, laboratories;Stanford University School of Medicineconverted the Page Mill building to offices and medical laboratories.[126]
Management
[edit]![Elizabeth Holmes, the chief executive officer and founder of Theranos in 2013.](https://upload.wikimedia.org/wikipedia/commons/thumb/4/45/Elizabeth_Holmes_at_a_Nuclear_nonproliferation_discussion_in_2013_-_130417-D-NI589-107_%28cropped%29.jpg/220px-Elizabeth_Holmes_at_a_Nuclear_nonproliferation_discussion_in_2013_-_130417-D-NI589-107_%28cropped%29.jpg)
From its incorporation in 2003 until 2018, Holmes was the company's chief executive officer. She recruitedChanning Robertson,a chemical-engineering professor at Stanford, to be a technical advisor and the company's first board member during its early years. Holmes's then-boyfriendRamesh Balwani,a software engineer whom Holmes had met during high school, joined the company as its president and chief operating officer in 2009.[129]In July 2011 Holmes was introduced to former U.S. Secretary of StateGeorge Shultz,who joined the Theranos board of directors that month.[130]Over the next three years, Shultz helped to introduce almost all the outside directors on the "all-star board", which includedWilliam Perry(formerU.S. Secretary of Defense),Henry Kissinger(formerU.S. Secretary of State),Sam Nunn(formerU.S. Senator),Bill Frist(former U.S. Senator, senate majority leader and heart-transplant surgeon),Gary Roughead(Admiral,USN,retired),Jim Mattis(General,USMC),Richard Kovacevich(former Wells Fargo Chairman and CEO) andRiley P. Bechtel(chairman of the board and former CEO atBechtel Group).[130][131][132]The board was criticized for consisting "mainly of directors with diplomatic or military backgrounds".[11]
In April 2016 Theranos announced its medical advisory board which included past presidents or board members of theAmerican Association for Clinical Chemistry.[133]Members were invited to review the company's proprietary technologies and advise on the integration into clinical practice.[133]The board included members with relevant biomedical expertise such as past president of theAmerican Association for Clinical ChemistrySusan A. Evans;William Foege,former director of the U.S.Centers for Disease Control and Prevention(CDC); David Helfet, director of the Orthopedic Trauma Service at the Hospital for Special Surgery; and professors Ann M. Gronowski, Larry J. Kricka, Jack Ladenson, Andy O. Miller and Steven Spitalnik.[134][135]
Balwani left his position as president and COO in May 2016. At that time, the company announced its new board members, Fabrizio Bonanni (former executive vice president ofAmgen), Richard Kovacevich and William Foege, who would help to publicly introduce its technologies.[136][137][138]In May 2016 members of the Theranos board of directors were:[139]
- Elizabeth Holmes,founder and CEO
- Riley Bechtel, formerBechtel GroupCEO
- David Boies,a founder and the chairman of Boies Schiller Flexner
- William Foege,former director of the CDC
- Richard Kovacevich, former CEO and chairman ofWells Fargo
- Jim Mattis,laterU.S. Secretary of Defense
- Fabrizio Bonanni, former executive vice president of Amgen
It was announced in November 2016 that the celebrity-studded "board of counselors" would be scrapped in January 2017.[140]In December 2016 Theranos announced that its management team would be restructured with the departure of Riley Bechtel. In January 2017, incoming U.S. Secretary of Defense nominee James Mattis resigned from the Theranos board.[141]In December 2016, the Theranos board of directors included:[142]
- Elizabeth Holmes
- William Foege
- Fabrizio Bonanni
- Daniel Warmenhoven, formerNetAppCEO, replacing Bechtel
Valuation
[edit]Theranos raised millions of dollars in its first years. In 2004, Theranos was based in a rented basement near the Stanford campus.[143]By December 2004, the company had raised more than $6 million from investors at a valuation of $30 million.[144]The company had about $45 million total fundraising afterSeries B and Series Cfunding in 2006.[145]Theranos raised an additional $45 million in 2010 at a valuation of $1 billion.[144][146]The company had significant news coverage starting in September 2013 after profiles in theSan Francisco Business TimesandThe Wall Street Journal.[11]By 2014, Theranos had raised more than $400 million with an estimated value of $9 billion.[147]Theranos raised more than $700 million from venture capitalists and private investors,[148]resulting in a $10 billion valuation at its peak in 2013 and 2014.[15][149]In 2016,Forbesrevised the estimated net worth of the company to $800 million taking into account the $724 million of capital raised.[9]Between 2004 and 2016, the amount of available cash from investors forprivate equity/venture capitalfirms to invest in companies grew from $400 billion to $1.5 trillion.[150]It was a period of plentiful capital available where investors were pressured to find investment targets to deploy capital on. In the Theranos case, insufficientdue diligenceand fraudulent business practices led to the losses for investors.[151]
In May 2017 participating shareholders provided a release of any potential claims against Theranos in exchange for shares of the company's newpreferred stock.Holders of more than 99% of the shares elected to participate. Holmes contributed shares to the company and gave upequityto offset potential dilution to non-participating shareholders.[152]In May 2018John Carreyroureported that American business and government leaders lost more than $600 million by privately investing in Theranos.[153]Major investments had been made by theWalton family($150 million),Rupert Murdoch($121 million),Betsy DeVos($100 million) and the Cox family (ofCox Media Group) ($100 million).[61]The final liquidation of the company in September 2018 rendered these investments worthless.[94]
Books and documentaries
[edit]John Carreyrou, aWall Street Journaljournalist whose work exposed Theranos, published a book-length treatment in May 2018 titledBad Blood: Secrets and Lies in a Silicon Valley Startup.[154]A film version was reportedly scheduled for release in 2020, starringJennifer Lawrenceas Elizabeth Holmes, written byVanessa Taylorand directed byAdam McKay.[155][156]In January 2022, McKay stated that preparations for the film had resumed, and that Lawrence was working on learning Holmes's speech pattern.[157]However, in November 2022, Lawrence announced she would no longer be involved with the project.[158]
In January 2019ABC News Nightlinereleased a podcast and documentary about the Holmes/Theranos story calledThe Dropout.[159]A miniseries withthe same name,based on the eponymous podcast, premiered onHuluin the US,Star+in Latin America andDisney+internationally in March 2022, withAmanda Seyfriedas Holmes.[160]Also in January 2019 adocumentary filmentitledThe Inventor: Out for Blood in Silicon Valleyabout Holmes and Theranos was released. Directed byAlex Gibney,it made its debut at theSundance Film Festivaland was released to the general public in March 2019 onHBOplatforms.[161][162]
See also
[edit]- Ian Gibbons– Theranos's chief scientist who died by suicide in 2013
- Richard Fuisz– defendant in a patent related lawsuit filed by Theranos and its CEO
Notes
[edit]- ^abSources have reported that Theranos became defunct on September 4th due to an email sent by then CEO David Taylor to Theranos shareholders.[1]Other reports state that Theranos remained active until its patents and most of its remaining assets were transferred toFortress Investment Groupthe following week on September 12th.[2]
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External links
[edit]- Official website(Archived)
- Theranos Original Pitchdeck 2006, "A Presentation for Investors"
- "Elizabeth Holmes on Her Billion-Dollar Health Care Idea",Charlie RoseviaYouTube,June 3, 2015.
- Tobak, Steve,"After the Theranos Mess, Can We Finally Quit Idolizing Entrepreneurs?" (Commentary),Fortunemagazine. May 27, 2016.
- "Theranos, CEO Holmes, and Former President Balwani Charged With Massive Fraud"(Press release). The Securities and Exchange Commission.RetrievedMarch 14,2018.
- Theranos' Fatal Flaws Were in Plain Sight,Barry Ritholz. Bloomberg Opinion. 31 May 2018.
- The Rise and Fall of Elizabeth Holmes,Avery Hartmans.Business Insider Australia.April 21, 2018.
- 2003 establishments in California
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- American companies disestablished in 2018
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- Biotechnology companies disestablished in 2018
- Biotechnology companies established in 2003
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- Companies based in Palo Alto, California
- Confidence tricks
- Corruption in the United States
- Defunct companies based in the San Francisco Bay Area
- Defunct health care companies of the United States
- Defunct Softbank portfolio companies
- Fraud in the United States
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