Thymus hyperplasia
| Thymus hyperplasia | |
|---|---|
| Other names | Thymic hyperplasia |
| Specialty | Immunology |
Thymus hyperplasiarefers to an enlargement ( "hyperplasia") of thethymus.[1]
It is not always a disease state. The size of the thymus usually peaks during adolescence and atrophies in the following decades. Before the immune function of the thymus was well understood, the enlargement was sometimes seen as a cause for alarm, and justification for surgical reduction. This approach is much less common today.
It can be associated withmyasthenia gravis.[2][3]Magnetic resonance imagingcan be used to distinguish it fromthymoma.[4]
Thymic hyperplasia
[edit]Thymic hyperplasia can be divided into three groups namely, those without any pre-existing medical condition, those recovering from a pre-existing medical condition such as pneumonia, corticosteroid therapy, radiation therapy, chemotherapy, surgery, and burns, and those with other disorders such as hyperthyroidism, juvenilemyasthenia gravis,[5]sarcoidosis,pure red cell aplasia.[6]
References
[edit]- ^Surgery of Thymus GlandateMedicine
- ^"Thymus, hyperplasia".Medcyclopaedia.General Electric.[dead link]
- ^Murakami M, Hosoi Y, Negishi T, et al. (November 1996)."Thymic hyperplasia in patients with Graves' disease. Identification of thyrotropin receptors in human thymus".Journal of Clinical Investigation.98(10): 2228–34.doi:10.1172/JCI119032.PMC507671.PMID8941638.
- ^Inaoka, Tsutomu; Takahashi, Koji; Mineta, Masayuki; Yamada, Tomonori; Shuke, Noriyuki; Okizaki, Atsutaka; Nagasawa, Kenichi; Sugimori, Hiroyuki; Aburano, Tamio (June 2007). "Thymic Hyperplasia and Thymus Gland Tumors: Differentiation with Chemical Shift MR Imaging".Radiology.243(3): 869–876.doi:10.1148/radiol.2433060797.PMID17463136.
- ^Hayashi, Masatoshi (2 December 2023)."Pathophysiology of Childhood-Onset Myasthenia: Abnormalities of Neuromuscular Junction and Autoimmunity and Its Background".Pathophysiology.30(4): 599–617.doi:10.3390/pathophysiology30040043.PMC10747330.PMID38133144.
- ^Nasseri, Farbod; Eftekhari, Farzin (March 2010). "Clinical and Radiologic Review of the Normal and Abnormal Thymus: Pearls and Pitfalls".RadioGraphics.30(2): 413–428.doi:10.1148/rg.302095131.PMID20228326.