A curated list for awesome N-Acetylcysteine (N.A.C.) studies & sources
N-acetyl cysteine (NAC), as a nutritional supplement, is a greatly applied antioxidant in vivo and in vitro. NAC is a precursor of L-cysteine that results in glutathione elevation biosynthesis. It acts directly as a scavenger of free radicals, especially oxygen radicals. NAC is a powerful antioxidant. It is also recommended as a potential treatment option for different disorders resulted from generation of free oxygen radicals. Additionally, it is a protected and endured mucolytic drug that mellows tenacious mucous discharges. It has been used for treatment of various diseases in a direct action or in a combination with some other medications.
- S-linolenoyl glutathione intake extends life-span and stress resistance via Sir-2.1 upregulation in Caenorhabditis elegans
- Mechanisms underlying the cardioprotective effect of L-cysteine
- Cysteine metabolism and metal toxicity
- A Review on Various Uses of N-Acetyl Cysteine
- Oxidative Stress and Inflammation in Hepatic Diseases: Therapeutic Possibilities of N-Acetylcysteine
- Glutamate - Neuroscience Bookshelf
- The chemistry and biological activities of N-acetylcysteine - ScienceDirect
- N-acetylcysteine in psychiatry: current therapeutic evidence and potential mechanisms of action
- N-Acetylcysteine in depressive symptoms and functionality: a systematic review and meta-analysis
- N-acetylcysteine augmentation therapy for moderate-to-severe obsessive-compulsive disorder: randomized, double-blind, placebo-controlled trial
- Synaptic and cellular changes induced by the schizophrenia susceptibility gene G72 are rescued by N-acetylcysteine treatment
- N-acetylcysteine, a glutamate modulator, in the treatment of trichotillomania: a double-blind, placebo-controlled study
- N-Acetylcysteine (NAC) in Young Marijuana Users: An Open-Label Pilot Study
- Potential Role of N -Acetylcysteine in the Management of Substance Use Disorders | SpringerLink
- The promise of N-acetylcysteine in neuropsychiatry
- Efficacy of Ascorbic Acid (Vitamin C) and/N-Acetylcysteine (NAC) Supplementation on Nutritional and Antioxidant Status of Male Chronic Obstructive..
- The role for N-acetylcysteine in the management of COPD
- A Review on Various Uses of N-Acetyl Cysteine: Alzheimer
- Lipoic acid and N-acetyl cysteine decrease mitochondrial-related oxidative stress in Alzheimer disease patient fibroblasts
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2129149/
- A Review on Various Uses of N-Acetyl Cysteine: Parkinson
- N-acetyl-cysteine in the treatment of Parkinson's disease. What are we waiting for?
- Targeting α-synuclein for treatment of Parkinson's disease: mechanistic and therapeutic considerations.
- Efficacy of Ascorbic Acid (Vitamin C) and/N-Acetylcysteine (NAC) Supplementation on Nutritional and Antioxidant Status of Male Chronic Obstructive..
- The role for N-acetylcysteine in the management of COPD
- Effect of High/Low Dose N-Acetylcysteine on Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-analysis: COPD: Journal of Chronic Obstructive Pulmonary Disease: Vol 11, No 3
- N-acetylcysteine in COPD: why, how, and when?
- Efficacy of oral long-term N-acetylcysteine in chronic bronchopulmonary disease: a meta-analysis of published double-blind, placebo-controlled clin..
- [N-acetylcystein in the therapy of chronic bronchitis]
- The effect of oral N-acetylcysteine in chronic bronchitis: a quantitative systematic review | European Respiratory Society
- High-dose oral N-acetylcysteine, a glutathione prodrug, modulates inflammation in cystic fibrosis
- The role of antioxidant therapy in the treatment of male infertility: an overview
- A Preliminary Study: N-acetyl-L-cysteine Improves Semen Quality following Varicocelectomy
- Efficacy of selenium and/or N-acetyl-cysteine for improving semen parameters in infertile men: a double-blind, placebo controlled, randomized study
- N-Acetyl cysteine and clomiphene citrate for induction of ovulation in polycystic ovary syndrome: a cross-over trial
- The molecular basis for oxidative stress-induced insulin resistance
- L-cysteine supplementation lowers blood glucose, glycated hemoglobin, CRP, MCP-1, and oxidative stress and inhibits NF-kappaB activation in the liv..
- N-acetylcysteine Protects Mice from High Fat Diet-induced Metabolic Disorders
- N-Acetyl Cysteine improves the diabetic cardiac function: possible role of fibrosis inhibition
- N-Acetyl Cysteine improves the diabetic cardiac function: possible role of fibrosis inhibition
- N-acetyl-L-cysteine exerts direct anti-aggregating effect on human platelets
- Green tea polyphenols inhibit human vascular smooth muscle cell proliferation stimulated by native low-density lipoprotein
- Glutathione and immune function
- HIV-induced cysteine deficiency and T-cell dysfunction--a rationale for treatment with N-acetylcysteine
- Glutathione depletion in HIV-infected patients: role of cysteine deficiency and effect of oral N-acetylcysteine
- Influence of glutathione availability on cell damage induced by human immunodeficiency virus type 1 viral protein R
- N-acetyl-L-cysteine (NAC) inhibits virus replication and expression of pro-inflammatory molecules in A549 cells infected with highly pathogenic H5N..
- N-acetyl cysteine and penicillamine induce apoptosis via the ER stress response-signaling pathway
- N-acetyl cysteine inhibits human signet ring cell gastric cancer cell line (SJ-89) cell growth by inducing apoptosis and DNA synthesis arrest
- N-acetyl cysteine protects against ionizing radiation-induced DNA damage but not against cell killing in yeast and mammals
- S-linolenoyl glutathione intake extends life-span and stress resistance via Sir-2.1 upregulation in Caenorhabditis elegans
- Mechanisms underlying the cardioprotective effect of L-cysteine
- Cysteine metabolism and metal toxicity
- A Review on Various Uses of N-Acetyl Cysteine
- Oxidative Stress and Inflammation in Hepatic Diseases: Therapeutic Possibilities of N-Acetylcysteine
- Glutamate - Neuroscience Bookshelf
- The chemistry and biological activities of N-acetylcysteine - ScienceDirect
- N-acetylcysteine in psychiatry: current therapeutic evidence and potential mechanisms of action
- N-Acetylcysteine in depressive symptoms and functionality: a systematic review and meta-analysis
- N-acetylcysteine augmentation therapy for moderate-to-severe obsessive-compulsive disorder: randomized, double-blind, placebo-controlled trial
- Synaptic and cellular changes induced by the schizophrenia susceptibility gene G72 are rescued by N-acetylcysteine treatment
- N-acetylcysteine, a glutamate modulator, in the treatment of trichotillomania: a double-blind, placebo-controlled study
- N-Acetylcysteine (NAC) in Young Marijuana Users: An Open-Label Pilot Study
- Potential Role of N -Acetylcysteine in the Management of Substance Use Disorders | SpringerLink
- The promise of N-acetylcysteine in neuropsychiatry
- Efficacy of Ascorbic Acid (Vitamin C) and/N-Acetylcysteine (NAC) Supplementation on Nutritional and Antioxidant Status of Male Chronic Obstructive..
- The role for N-acetylcysteine in the management of COPD
- Effect of High/Low Dose N-Acetylcysteine on Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-analysis: COPD: Journal of Chronic Obstructive Pulmonary Disease: Vol 11, No 3
- N-acetylcysteine in COPD: why, how, and when?
- Efficacy of oral long-term N-acetylcysteine in chronic bronchopulmonary disease: a meta-analysis of published double-blind, placebo-controlled clin..
- [N-acetylcystein in the therapy of chronic bronchitis]
- The effect of oral N-acetylcysteine in chronic bronchitis: a quantitative systematic review | European Respiratory Society
- High-dose oral N-acetylcysteine, a glutathione prodrug, modulates inflammation in cystic fibrosis
- N-acetylcysteine protects memory decline induced by streptozotocin in mice
- The role of antioxidant therapy in the treatment of male infertility: an overview
- A Preliminary Study: N-acetyl-L-cysteine Improves Semen Quality following Varicocelectomy
- Efficacy of selenium and/or N-acetyl-cysteine for improving semen parameters in infertile men: a double-blind, placebo controlled, randomized study
- N-Acetyl cysteine and clomiphene citrate for induction of ovulation in polycystic ovary syndrome: a cross-over trial
- The molecular basis for oxidative stress-induced insulin resistance
- L-cysteine supplementation lowers blood glucose, glycated hemoglobin, CRP, MCP-1, and oxidative stress and inhibits NF-kappaB activation in the liv..
- N-acetylcysteine Protects Mice from High Fat Diet-induced Metabolic Disorders
- N-Acetyl Cysteine improves the diabetic cardiac function: possible role of fibrosis inhibition
- N-acetyl-L-cysteine exerts direct anti-aggregating effect on human platelets
- Green tea polyphenols inhibit human vascular smooth muscle cell proliferation stimulated by native low-density lipoprotein
- Glutathione and immune function
- HIV-induced cysteine deficiency and T-cell dysfunction--a rationale for treatment with N-acetylcysteine
- Glutathione depletion in HIV-infected patients: role of cysteine deficiency and effect of oral N-acetylcysteine
- Influence of glutathione availability on cell damage induced by human immunodeficiency virus type 1 viral protein R
- N-acetyl-L-cysteine (NAC) inhibits virus replication and expression of pro-inflammatory molecules in A549 cells infected with highly pathogenic H5N..
- N-acetyl cysteine and penicillamine induce apoptosis via the ER stress response-signaling pathway
- N-acetyl cysteine inhibits human signet ring cell gastric cancer cell line (SJ-89) cell growth by inducing apoptosis and DNA synthesis arrest
- N-acetyl cysteine protects against ionizing radiation-induced DNA damage but not against cell killing in yeast and mammals
- N-acetylcysteine for antioxidant therapy: pharmacology and clinical utility
- Pharmacokinetics of N-acetylcysteine in man
- Lipoic acid and N-acetyl cysteine decrease mitochondrial-related oxidative stress in Alzheimer disease patient fibroblasts