KCNK3
Potassium channel subfamily K member 3adalahproteinyang disandikan olehgenKCNK3dalam tubuh manusia.[1][2][3][4]KCNK3 diketahui telah berinteraksi denganYWHAB[5]danS100A10.[6]
Beberapa mutasi terhadap gen ini telah ditemukan oleh para peneliti. Salah satunya adalah mutasi yang dapat menyebabkanhipertensi paru.[7]
Referensi
[sunting|sunting sumber]- ^Duprat F, Lesage F, Fink M, Reyes R, Heurteaux C, Lazdunski M (Dec 1997)."TASK, a human background K+ channel to sense external pH variations near physiological pH".EMBO J.16(17): 5464–71.doi:10.1093/emboj/16.17.5464.PMC1170177
.PMID9312005.
- ^Lesage F, Lazdunski M (Oct 1998). "Mapping of human potassium channel genes TREK-1 (KCNK2) and TASK (KCNK3) to chromosomes 1q41 and 2p23".Genomics.51(3): 478–9.doi:10.1006/geno.1998.5397.PMID9721223.
- ^Goldstein SA, Bayliss DA, Kim D, Lesage F, Plant LD, Rajan S (Dec 2005). "International Union of Pharmacology. LV. Nomenclature and molecular relationships of two-P potassium channels".Pharmacol Rev.57(4): 527–40.doi:10.1124/pr.57.4.12.PMID16382106.
- ^"Entrez Gene: KCNK3 potassium channel, subfamily K, member 3".
- ^O'Kelly, Ita; Butler Margaret H; Zilberberg Noam; Goldstein Steve A N (Nov 2002). "Forward transport. 14-3-3 binding overcomes retention in endoplasmic reticulum by dibasic signals".Cell.United States.111(4): 577–88.doi:10.1016/S0092-8674(02)01040-1.ISSN0092-8674.PMID12437930.
- ^Girard, Christophe; Tinel Norbert; Terrenoire Cécile; Romey Georges; Lazdunski Michel; Borsotto Marc (Sep 2002)."p11, an annexin II subunit, an auxiliary protein associated with the background K+ channel, TASK-1".EMBO J.England.21(17): 4439–48.doi:10.1093/emboj/cdf469.ISSN0261-4189.PMC125412 .PMID12198146.
- ^Ma L, Roman-Campos D, Austin ED. (2013)."A novel channelopathy in pulmonary arterial hypertension".N Engl J Med.(dalam bahasa Inggris) (369): 351-361.