Flukonazol
Izgled
(IUPAC) ime | |||
---|---|---|---|
2-(2,4-difluorofenil)-1,3-bis(1H-1,2,4-triazol-1-il)propan-2-ol | |||
Klinički podaci | |||
Robne marke | Biocanol, Biozolene, Diflucan, Elazor | ||
AHFS/Drugs.com | Monografija | ||
Identifikatori | |||
CAS broj | 86386-73-4 | ||
ATC kod | D01AC15,J02AC01 | ||
PubChem[1][2] | 3365 | ||
DrugBank | DB00196 | ||
ChemSpider[3] | 3248 | ||
ChEMBL[4] | CHEMBL46081 | ||
Hemijski podaci | |||
Formula | C13H12F2N6O | ||
Mol. masa | 306.2708 | ||
SMILES | eMolekuli&PubHem | ||
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Fizički podaci | |||
Tačka topljenja | 138-140 °C (-82 °F) | ||
Farmakokinetičkipodaci | |||
Poluvreme eliminacije | 30 sati | ||
Izlučivanje | 80% urinom | ||
Farmakoinformacioni podaci | |||
Trudnoća | ? | ||
Pravni status | |||
Način primene | Oralno; Intravenozno |
Flukonazoljetriazolniantifungalni agens koji se koristi za tretmanOropharyngeal candidiasisiCryptococcal meningitiskod obolelih odside.[5][6]
- ↑Li Q, Cheng T, Wang Y, Bryant SH (2010).„PubChem as a public resource for drug discovery.”.Drug Discov Today15(23-24): 1052-7.DOI:10.1016/j.drudis.2010.10.003.PMID20970519.
- ↑Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”.Annual Reports in Computational Chemistry4:217-241.DOI:10.1016/S1574-1400(08)00012-1.
- ↑Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010).„Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”.J Cheminform2(1): 3.DOI:10.1186/1758-2946-2-3.PMID20331846.
- ↑Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”.Nucleic Acids Res40(Database issue): D1100-7.DOI:10.1093/nar/gkr777.PMID21948594.
- ↑Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS (2011). „DrugBank 3.0: a comprehensive resource for omics research on drugs”.Nucleic Acids Res.39(Database issue): D1035-41.PMID21059682.
- ↑Wishart DS, Knox C, Guo AC, Cheng D, Shrivastava S, Tzur D, Gautam B, Hassanali M (2008). „DrugBank: a knowledgebase for drugs, drug actions and drug targets”.Nucleic Acids Res36(Database issue): D901-6.PMID18048412.