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Flukonazol

Izvor: Wikipedija
Flukonazol
(IUPAC) ime
2-(2,4-difluorofenil)-1,3-bis(1H-1,2,4-triazol-1-il)propan-2-ol
Klinički podaci
Robne marke Biocanol, Biozolene, Diflucan, Elazor
AHFS/Drugs.com Monografija
Identifikatori
CAS broj 86386-73-4
ATC kod D01AC15,J02AC01
PubChem[1][2] 3365
DrugBank DB00196
ChemSpider[3] 3248
ChEMBL[4] CHEMBL46081DaY
Hemijski podaci
Formula C13H12F2N6O
Mol. masa 306.2708
SMILES eMolekuli&PubHem
Fizički podaci
Tačka topljenja 138-140 °C (-82 °F)
Farmakokinetičkipodaci
Poluvreme eliminacije 30 sati
Izlučivanje 80% urinom
Farmakoinformacioni podaci
Trudnoća ?
Pravni status
Način primene Oralno; Intravenozno

Flukonazoljetriazolniantifungalni agens koji se koristi za tretmanOropharyngeal candidiasisiCryptococcal meningitiskod obolelih odside.[5][6]

Reference

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  1. Li Q, Cheng T, Wang Y, Bryant SH (2010).„PubChem as a public resource for drug discovery.”.Drug Discov Today15(23-24): 1052-7.DOI:10.1016/j.drudis.2010.10.003.PMID20970519.edit
  2. Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”.Annual Reports in Computational Chemistry4:217-241.DOI:10.1016/S1574-1400(08)00012-1.
  3. Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010).„Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”.J Cheminform2(1): 3.DOI:10.1186/1758-2946-2-3.PMID20331846.edit
  4. Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”.Nucleic Acids Res40(Database issue): D1100-7.DOI:10.1093/nar/gkr777.PMID21948594.edit
  5. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS (2011). „DrugBank 3.0: a comprehensive resource for omics research on drugs”.Nucleic Acids Res.39(Database issue): D1035-41.PMID21059682.
  6. Wishart DS, Knox C, Guo AC, Cheng D, Shrivastava S, Tzur D, Gautam B, Hassanali M (2008). „DrugBank: a knowledgebase for drugs, drug actions and drug targets”.Nucleic Acids Res36(Database issue): D901-6.PMID18048412.

Spoljašnje veze

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