Dihidrotakisterol
Izgled
(IUPAC) ime | |||
---|---|---|---|
(1S,3E,4S)-3-[(2E)-2-[(1R,3aS,7aR)-1-[(E,2R,5R)-5,6-Dimetilhept-3-en-2-il]-7a-metil-2,3,3a,5,6,7-heksahidro-1H-inden-4-iliden]etiliden]-4-metilcikloheksan-1-ol | |||
Klinički podaci | |||
AHFS/Drugs | Mikromedeks, detaljne potrošačke informacije | ||
MedlinePlus | a682335 | ||
Identifikatori | |||
CAS broj | 67-96-9 | ||
ATC kod | A11CC02 | ||
PubChem[1][2] | 5311071 | ||
DrugBank | DB01070 | ||
ChemSpider[3] | 4470607 | ||
UNII | R5LM3H112R | ||
KEGG[4] | D00299 | ||
ChEBI | CHEBI:4591 | ||
Hemijski podaci | |||
Formula | C28H46O | ||
Mol. masa | 398,664 g/mol | ||
SMILES | eMolekuli&PubHem | ||
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Farmakoinformacioni podaci | |||
Trudnoća | ? | ||
Pravni status |
Dihidrotakisterol(DHT) je sintetički analogvitamina Dkoji se aktivira ujetri,te mu nije potrebnarenalnahidroksilacija poput vitamina D2(ergokalciferola) i vitamina D3(holekalciferola). DHT ima brz početak dejstva (2 sata), kratakpoluživot,i vrši veći uticaj namineralizacijukoštanih soli od vitamina D.[5]
- ↑Li Q, Cheng T, Wang Y, Bryant SH (2010).„PubChem as a public resource for drug discovery.”.Drug Discov Today15(23-24): 1052-7.DOI:10.1016/j.drudis.2010.10.003.PMID20970519.
- ↑Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”.Annual Reports in Computational Chemistry4:217-241.DOI:10.1016/S1574-1400(08)00012-1.
- ↑Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010).„Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”.J Cheminform2(1): 3.DOI:10.1186/1758-2946-2-3.PMID20331846.
- ↑Joanne Wixon, Douglas Kell (2000).„Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”.Yeast17(1): 48–55.DOI:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H.
- ↑R. Gagnon, G. W. Ogden, G. Just, M. Kaye (1974).„Comparison of Dihydrotachysterol and 5,6-trans Vitamin D3 on Intestinal Calcium Absorption in Patients with Chronic Renal Failure”.Canadian Journal of Physiology and Pharmacology52:272-274.DOI:10.1139/y74-037.