Dihidrotakisterol

Dihidrotakisterol
(IUPAC) ime
	(1S,3E,4S)-3-[(2E)-2-[(1R,3aS,7aR)-1-[(E,2R,5R)-5,6-Dimetilhept-3-en-2-il]-7a-metil-2,3,3a,5,6,7-heksahidro-1H-inden-4-iliden]etiliden]-4-metilcikloheksan-1-ol
Klinički podaci
AHFS/Drugs	Mikromedeks, detaljne potrošačke informacije
MedlinePlus	a682335
Identifikatori
CAS broj	67-96-9
ATC kod	A11CC02
PubChem	5311071
DrugBank	DB01070
ChemSpider	4470607
UNII	R5LM3H112R
KEGG	D00299
ChEBI	CHEBI:4591
Hemijski podaci
Formula	C28H46O
Mol. masa	398,664 g/mol
SMILES	eMolekuli&PubHem
InChI
	InChI=1S/C28H46O/c1-19(2)20(3)9-10-22(5)26-15-16-27-23(8-7-17-28(26,27)6)12-13-24-18-25(29)14-11-21(24)4/h9-10,12-13,19-22,25-27,29H,7-8,11,14-18H2,1-6H3/b10-9+,23-12+,24-13+/t20-,21-,22+,25-,26+,27-,28+/m0/s1; Key: ILYCWAKSDCYMBB-OPCMSESCSA-N
Farmakoinformacioni podaci
Trudnoća	?
Pravni status

Dihidrotakisterol(DHT) je sintetički analogvitamina Dkoji se aktivira ujetri,te mu nije potrebnarenalnahidroksilacija poput vitamina D₂(ergokalciferola) i vitamina D₃(holekalciferola). DHT ima brz početak dejstva (2 sata), kratakpoluživot,i vrši veći uticaj namineralizacijukoštanih soli od vitamina D.^[5]

Reference

↑Li Q, Cheng T, Wang Y, Bryant SH (2010).„PubChem as a public resource for drug discovery.”.Drug Discov Today15(23-24): 1052-7.DOI:10.1016/j.drudis.2010.10.003.PMID 20970519.edit
↑Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”.Annual Reports in Computational Chemistry4:217-241.DOI:10.1016/S1574-1400(08)00012-1.
↑Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010).„Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”.J Cheminform2(1): 3.DOI:10.1186/1758-2946-2-3.PMID 20331846.edit
↑Joanne Wixon, Douglas Kell (2000).„Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”.Yeast17(1): 48–55.DOI:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H.
↑R. Gagnon, G. W. Ogden, G. Just, M. Kaye (1974).„Comparison of Dihydrotachysterol and 5,6-trans Vitamin D3 on Intestinal Calcium Absorption in Patients with Chronic Renal Failure”.Canadian Journal of Physiology and Pharmacology52:272-274.DOI:10.1139/y74-037.

Spoljašnje veze

	Portal Medicina
	Portal Hemija

[1] Li Q, Cheng T, Wang Y, Bryant SH (2010).„PubChem as a public resource for drug discovery.”.Drug Discov Today15(23-24): 1052-7.DOI:10.1016/j.drudis.2010.10.003.PMID 20970519.edit

[2] Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”.Annual Reports in Computational Chemistry4:217-241.DOI:10.1016/S1574-1400(08)00012-1.

[3] Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010).„Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”.J Cheminform2(1): 3.DOI:10.1186/1758-2946-2-3.PMID 20331846.edit

[4] Joanne Wixon, Douglas Kell (2000).„Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”.Yeast17(1): 48–55.DOI:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H.

[5] R. Gagnon, G. W. Ogden, G. Just, M. Kaye (1974).„Comparison of Dihydrotachysterol and 5,6-trans Vitamin D3 on Intestinal Calcium Absorption in Patients with Chronic Renal Failure”.Canadian Journal of Physiology and Pharmacology52:272-274.DOI:10.1139/y74-037.

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