SARS-CoV

	Coronavirus
	Elektronmikroskopsbild av sars-virion.
Systematik
Ordning	Nidovirales
Familj	Coronaviridae
Underfamilj	Orthocoronavirinae
Släkte	Betacoronavirus
Art	Severe acute respiratory syndrome-related coronavirus
Virusstam
	Severe acute respiratory syndrome coronavirus
Synonymer
	SARS coronavirus; Severe acute respiratory syndrome coronavirus;

Severe acute respiratory syndrome coronavirus(SARS-CoV) är den stam avcoronavirussom orsakar sjukdomensars(severe acute respiratory syndrome).^[2]Coronavirus har enkelsträngat positivtRNA-genom,ett så kallatsRNA-virus,och infekterarepitelcelleri lungorna.^[3]^[4]Viruset infekterar människor, fladdermöss ochpalmmårdar.^[5]^[6]

I slutet av 2002 rapporterades om en ny epidemi i Asien som visade sig bero på SARS-CoV.^[7]^[8]Sjukdomensarsorsakade runt 8000 sjukdomsfall med över 750 dödsfall i sviterna.^[9]

En pandemipå grund av sjukdomenCOVID-192019–2021 visade stora likheter med sars, och viruset identifierades somsars-cov-2,ännu en stam avsars-relaterade coronavirus.

Referenser

Noter

^”ICTV Taxonomy history:Severe acute respiratory syndrome-related coronavirus”(på engelska) (html).International Committee on Taxonomy of Viruses (ICTV).https://talk.ictvonline.org/taxonomy/p/taxonomy-history?taxnode_id=20181868.Läst 27 januari 2019.
^Thiel V (editor). (2007).Coronaviruses: Molecular and Cellular Biology(1st). Caister Academic Press.ISBN 978-1-904455-16-5
^Fehr, Anthony R.; Perlman, Stanley (2015).” Coronaviruses: An Overview of Their Replication and Pathogenesis”.Coronaviruses.Methods in Molecular Biology (Clifton, N.J.). "1282". sid. 1–23.doi:10.1007/978-1-4939-2438-7_1.ISBN 978-1-4939-2437-0.”SARS-CoV primarily infects epithelial cells within the lung. The virus is capable of entering macrophages and dendritic cells but only leads to an abortive infection [87,88].”
^Xing-Yi Ge, Jia-Lu Li, Xing-Lou Yang, et al. (2013).”Isolation and characterization of a bat SARS-like coronavirus that uses the ACE2 receptor”.Nature503 (7477): sid. 535–538.doi:10.1038/nature12711.PMID 24172901.
^Wong, Antonio C. P.; Li, Xin; Lau, Susanna K. P.; Woo, Patrick C. Y. (20 februari 2019).”Global Epidemiology of Bat Coronaviruses”.Viruses11 (2): sid. 174.doi:10.3390/v11020174.ISSN 1999-4915.PMID 30791586.”Most notably, horseshoe bats were found to be the reservoir of SARS-like CoVs, while palm civet cats are considered to be the intermediate host for SARS-CoVs [43,44,45].”.
^Li, Fang (oktober 2013).”Receptor recognition and cross-species infections of SARS coronavirus”.Antiviral Research100 (1): sid. 246–254.doi:10.1016/j.antiviral.2013.08.014.ISSN 0166-3542.PMID 23994189.”See Figure 6.”.
^”Remembering SARS: A Deadly Puzzle and the Efforts to Solve It”.Centers for Disease Control and Prevention. 11 april 2013. Arkiverad frånoriginaletden 1 augusti 2013.https://web.archive.org/web/20130801143131/http:// cdc.gov/about/history/sars/feature.htm.Läst 3 augusti 2013.
^”Coronavirus never before seen in humans is the cause of SARS”.United Nations World Health Organization. 16 april 2006. Arkiverad frånoriginaletden 12 augusti 2004.https://web.archive.org/web/20040812124322/http:// who.int/mediacentre/releases/2003/pr31/en/.Läst 5 juli 2006.
^Folkhälsomyndigheten(2020-01-21)Sjukdomsinformation om coronavirus inklusive sars och mers,läst 2020-01-31

Externa länkar

Wikimedia Commons har media som rörSARS-CoV.
Bilder & media

[TaxHist-1] ”ICTV Taxonomy history:Severe acute respiratory syndrome-related coronavirus”(på engelska) (html).International Committee on Taxonomy of Viruses (ICTV).https://talk.ictvonline.org/taxonomy/p/taxonomy-history?taxnode_id=20181868.Läst 27 januari 2019.

[Thiel-2] Thiel V (editor). (2007).Coronaviruses: Molecular and Cellular Biology(1st). Caister Academic Press.ISBN 978-1-904455-16-5

[3] Fehr, Anthony R.; Perlman, Stanley (2015).” Coronaviruses: An Overview of Their Replication and Pathogenesis”.Coronaviruses.Methods in Molecular Biology (Clifton, N.J.). "1282". sid. 1–23.doi:10.1007/978-1-4939-2438-7_1.ISBN 978-1-4939-2437-0.”SARS-CoV primarily infects epithelial cells within the lung. The virus is capable of entering macrophages and dendritic cells but only leads to an abortive infection [87,88].”

[:0-4] Xing-Yi Ge, Jia-Lu Li, Xing-Lou Yang, et al. (2013).”Isolation and characterization of a bat SARS-like coronavirus that uses the ACE2 receptor”.Nature503 (7477): sid. 535–538.doi:10.1038/nature12711.PMID 24172901.

[5] Wong, Antonio C. P.; Li, Xin; Lau, Susanna K. P.; Woo, Patrick C. Y. (20 februari 2019).”Global Epidemiology of Bat Coronaviruses”.Viruses11 (2): sid. 174.doi:10.3390/v11020174.ISSN 1999-4915.PMID 30791586.”Most notably, horseshoe bats were found to be the reservoir of SARS-like CoVs, while palm civet cats are considered to be the intermediate host for SARS-CoVs [43,44,45].”.

[6] Li, Fang (oktober 2013).”Receptor recognition and cross-species infections of SARS coronavirus”.Antiviral Research100 (1): sid. 246–254.doi:10.1016/j.antiviral.2013.08.014.ISSN 0166-3542.PMID 23994189.”See Figure 6.”.

[7] ”Remembering SARS: A Deadly Puzzle and the Efforts to Solve It”.Centers for Disease Control and Prevention. 11 april 2013. Arkiverad frånoriginaletden 1 augusti 2013.https://web.archive.org/web/20130801143131/http:// cdc.gov/about/history/sars/feature.htm.Läst 3 augusti 2013.

[8] ”Coronavirus never before seen in humans is the cause of SARS”.United Nations World Health Organization. 16 april 2006. Arkiverad frånoriginaletden 12 augusti 2004.https://web.archive.org/web/20040812124322/http:// who.int/mediacentre/releases/2003/pr31/en/.Läst 5 juli 2006.

[FHM-9] Folkhälsomyndigheten(2020-01-21)Sjukdomsinformation om coronavirus inklusive sars och mers,läst 2020-01-31

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