Leader
|
|
|
00000nz a2200037n 45 0 |
001
|
|
|
WKP|Q116785435
(VIAF cluster)
(Authority/Source Record)
|
003
|
|
|
WKP |
005
|
|
|
20241221010637.0 |
008
|
|
|
241221nneanz||abbn n and d |
035
|
|
|
‡a
(WKP)Q116785435
|
035
|
|
|
‡a
(OCoLC)Q116785435
|
100
|
0 |
|
‡a
Tse-I Lin
‡c
researcher
‡9
en
|
670
|
|
|
‡a
Author's 1,5-Benzodiazepine inhibitors of HCV NS5B polymerase
|
670
|
|
|
‡a
Author's 2'-Deoxy-2'-spirocyclopropylcytidine revisited: a new and selective inhibitor of the hepatitis C virus NS5B polymerase
|
670
|
|
|
‡a
Author's Discovery and early development of TMC647055, a non-nucleoside inhibitor of the hepatitis C virus NS5B polymerase
|
670
|
|
|
‡a
Author's Discovery of 1-((2R,4aR,6R,7R,7aR)-2-Isopropoxy-2-oxidodihydro-4H,6H-spiro[furo[3,2-d][1,3,2]dioxaphosphinine-7,2'-oxetan]-6-yl)pyrimidine-2,4(1H,3H)-dione (JNJ-54257099), a 3'-5'-Cyclic Phosphate Ester Prodrug of 2'-Deoxy-2'-Spirooxetane Uridine Tr
|
670
|
|
|
‡a
Author's Discovery of novel, potent and bioavailable proline-urea based macrocyclic HCV NS3/4A protease inhibitors.
|
670
|
|
|
‡a
Author's Evaluation of the anti-hepatitis C virus effect of novel potent, selective, and orally bioavailable JNK and VEGFR kinase inhibitors
|
670
|
|
|
‡a
Author's Finger-loop inhibitors of the HCV NS5b polymerase. Part 1: Discovery and optimization of novel 1,6- and 2,6-macrocyclic indole series
|
670
|
|
|
‡a
Author's Finger loop inhibitors of the HCV NS5b polymerase. Part II. Optimization of tetracyclic indole-based macrocycle leading to the discovery of TMC647055.
|
670
|
|
|
‡a
Author's In vitro activity and preclinical profile of TMC435350, a potent hepatitis C virus protease inhibitor
|
670
|
|
|
‡a
Author's Induced-fit binding of the macrocyclic noncovalent inhibitor TMC435 to its HCV NS3/NS4A protease target
|
670
|
|
|
‡a
Author's Structure-based macrocyclization yields hepatitis C virus NS5B inhibitors with improved binding affinities and pharmacokinetic properties
|
670
|
|
|
‡a
Author's Synthesis and SAR of potent inhibitors of the Hepatitis C virus NS3/4A protease: exploration of P2 quinazoline substituents
|
670
|
|
|
‡a
Author's TMC647055, a potent nonnucleoside hepatitis C virus NS5B polymerase inhibitor with cross-genotypic coverage
|
919
|
|
|
‡a
2deoxy2spirocyclopropylcytidinerevisitedanewandselectiveinhibitorofthehepatitis100virusns5bpolymerase
‡A
2'-Deoxy-2'-spirocyclopropylcytidine revisited: a new and selective inhibitor of the hepatitis C virus NS5B polymerase
‡9
1
|
919
|
|
|
‡a
discoveryandearlydevelopmentoftmc647055anonnucleosideinhibitorofthehepatitis100virusns5bpolymerase
‡A
Discovery and early development of TMC647055, a non-nucleoside inhibitor of the hepatitis C virus NS5B polymerase
‡9
1
|
919
|
|
|
‡a
tmc647055apotentnonnucleosidehepatitis100virusns5bpolymeraseinhibitorwithcrossgenotypiccoverage
‡A
TMC647055, a potent nonnucleoside hepatitis C virus NS5B polymerase inhibitor with cross-genotypic coverage
‡9
1
|
919
|
|
|
‡a
synthesisandsarofpotentinhibitorsofthehepatitis100virusns34aproteaseexplorationofp2quinazolinesubstituents
‡A
Synthesis and SAR of potent inhibitors of the Hepatitis C virus NS3/4A protease: exploration of P2 quinazoline substituents
‡9
1
|
919
|
|
|
‡a
15benzodiazepineinhibitorsofhcvns5bpolymerase
‡A
1,5-Benzodiazepine inhibitors of HCV NS5B polymerase
‡9
1
|
919
|
|
|
‡a
structurebasedmacrocyclizationyieldshepatitis100virusns5binhibitorswithimprovedbindingaffinitiesandpharmacokineticproperties
‡A
Structure-based macrocyclization yields hepatitis C virus NS5B inhibitors with improved binding affinities and pharmacokinetic properties
‡9
1
|
919
|
|
|
‡a
inducedfitbindingofthemacrocyclicnoncovalentinhibitortmc435toitshcvns3ns4aproteasetarget
‡A
Induced-fit binding of the macrocyclic noncovalent inhibitor TMC435 to its HCV NS3/NS4A protease target
‡9
1
|
919
|
|
|
‡a
invitroactivityandpreclinicalprofileoftmc435350apotenthepatitis100virusproteaseinhibitor
‡A
In vitro activity and preclinical profile of TMC435350, a potent hepatitis C virus protease inhibitor
‡9
1
|
919
|
|
|
‡a
fingerloopinhibitorsofthehcvns5bpolymerasepart2optimizationoftetracyclicindolebasedmacrocycleleadingtothediscoveryoftmc647055
‡A
Finger loop inhibitors of the HCV NS5b polymerase. Part II. Optimization of tetracyclic indole-based macrocycle leading to the discovery of TMC647055.
‡9
1
|
919
|
|
|
‡a
fingerloopinhibitorsofthehcvns5bpolymerasepart1discoveryandoptimizationofnovel16and26macrocyclicindoleseries
‡A
Finger-loop inhibitors of the HCV NS5b polymerase. Part 1: Discovery and optimization of novel 1,6- and 2,6-macrocyclic indole series
‡9
1
|
919
|
|
|
‡a
evaluationoftheantihepatitis100viruseffectofnovelpotentselectiveandorallybioavailablejnkandvegfrkinaseinhibitors
‡A
Evaluation of the anti-hepatitis C virus effect of novel potent, selective, and orally bioavailable JNK and VEGFR kinase inhibitors
‡9
1
|
919
|
|
|
‡a
discoveryofnovelpotentandbioavailableprolineureabasedmacrocyclichcvns34aproteaseinhibitors
‡A
Discovery of novel, potent and bioavailable proline-urea based macrocyclic HCV NS3/4A protease inhibitors.
‡9
1
|
919
|
|
|
‡a
discoveryof12r4ar6r7r7ar2isopropoxy2oxidodihydro4h6hspiro6ylpyrimidine241h3hdionejnj54257099a35cyclicphosphateesterprodrugof2deoxy2spirooxetaneuridinetr
‡A
Discovery of 1-((2R,4aR,6R,7R,7aR)-2-Isopropoxy-2-oxidodihydro-4H,6H-spiro[furo[3,2-d][1,3,2]dioxaphosphinine-7,2'-oxetan]-6-yl)pyrimidine-2,4(1H,3H)-dione (JNJ-54257099), a 3'-5'-Cyclic Phosphate Ester Prodrug of 2'-Deoxy-2'-Spirooxetane Uridine Tr
‡9
1
|
996
|
|
|
‡2
ISNI|000000005144899X
|
996
|
|
|
‡2
J9U|987007386512905171
|
996
|
|
|
‡2
ISNI|0000000076034080
|
996
|
|
|
‡2
LC|n 82051132
|
996
|
|
|
‡2
DNB|118980327
|
996
|
|
|
‡2
NDL|00470510
|
996
|
|
|
‡2
NLA|000036690241
|
996
|
|
|
‡2
ISNI|0000000063272047
|
996
|
|
|
‡2
ISNI|0000000063484162
|
996
|
|
|
‡2
SUDOC|112997392
|
996
|
|
|
‡2
NTA|304357936
|
996
|
|
|
‡2
CYT|AC000614682
|
996
|
|
|
‡2
LC|n 00004576
|
996
|
|
|
‡2
ISNI|0000000064045225
|
996
|
|
|
‡2
ISNI|0000000064357966
|
996
|
|
|
‡2
CAOONL|ncf11484697
|
996
|
|
|
‡2
J9U|987007386291605171
|
996
|
|
|
‡2
NLA|000036724775
|
996
|
|
|
‡2
NTA|127744622
|
996
|
|
|
‡2
ISNI|0000000027964062
|
996
|
|
|
‡2
NLA|000036596450
|
996
|
|
|
‡2
LC|no2008184695
|
996
|
|
|
‡2
NLA|000036679858
|
996
|
|
|
‡2
LC|n 82075582
|
996
|
|
|
‡2
NII|DA03718809
|
996
|
|
|
‡2
BNE|XX1129775
|
996
|
|
|
‡2
LC|no 98076155
|
996
|
|
|
‡2
NLA|000036623831
|
996
|
|
|
‡2
LC|n 94056437
|
996
|
|
|
‡2
DNB|1089442270
|
996
|
|
|
‡2
LC|n 84165298
|
996
|
|
|
‡2
NLA|000036679748
|
996
|
|
|
‡2
NII|DA07171442
|
996
|
|
|
‡2
NLA|000036696122
|
996
|
|
|
‡2
RERO|A021644162
|
996
|
|
|
‡2
ISNI|0000000377839923
|
996
|
|
|
‡2
CYT|AC000222698
|
996
|
|
|
‡2
NTA|140571094
|
996
|
|
|
‡2
NTA|155947060
|
996
|
|
|
‡2
NLA|000036621447
|
996
|
|
|
‡2
LC|no2018073387
|
996
|
|
|
‡2
BIBSYS|90306703
|
996
|
|
|
‡2
ISNI|000000006420103X
|
996
|
|
|
‡2
LC|no2010076681
|
996
|
|
|
‡2
NLA|000036625972
|
996
|
|
|
‡2
NLA|000036714410
|
996
|
|
|
‡2
NLA|000036653307
|
996
|
|
|
‡2
ISNI|000000044459869X
|
996
|
|
|
‡2
ISNI|0000000063523520
|
996
|
|
|
‡2
NLA|000036611732
|
996
|
|
|
‡2
PLWABN|9810549898705606
|
996
|
|
|
‡2
CAOONL|ncf10356479
|
996
|
|
|
‡2
CYT|AC000207774
|
996
|
|
|
‡2
BIBSYS|90375110
|
996
|
|
|
‡2
NLA|000036610918
|
996
|
|
|
‡2
NLA|000036602974
|
996
|
|
|
‡2
LC|n 87920569
|
996
|
|
|
‡2
BIBSYS|90211815
|
996
|
|
|
‡2
ISNI|000000008378375X
|
996
|
|
|
‡2
ISNI|000000008315278X
|
996
|
|
|
‡2
LC|n 84032080
|
996
|
|
|
‡2
SUDOC|185952372
|
996
|
|
|
‡2
J9U|987007264495705171
|
996
|
|
|
‡2
ISNI|0000000063495419
|
996
|
|
|
‡2
LC|no2008104419
|
996
|
|
|
‡2
NLA|000036630272
|
996
|
|
|
‡2
ISNI|0000000079533694
|
996
|
|
|
‡2
CAOONL|ncf10991937
|
996
|
|
|
‡2
ISNI|0000000063446430
|
996
|
|
|
‡2
ISNI|0000000064148152
|
996
|
|
|
‡2
ISNI|0000000063759293
|
996
|
|
|
‡2
SUDOC|074766279
|
996
|
|
|
‡2
DNB|1035286416
|
996
|
|
|
‡2
CAOONL|ncf10551025
|
996
|
|
|
‡2
ISNI|0000000063988184
|
997
|
|
|
‡a
0 0 lived 0 0
‡9
1
|