Leader
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00000nz a2200037n 45 0 |
001
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WKP|Q40077215
(VIAF cluster)
(Authority/Source Record)
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WKP |
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(WKP)Q40077215
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0000-0002-9315-5321
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orcid
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(OCoLC)Q40077215
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100
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Alex Thompson
‡c
investigador
‡9
ast
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375
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‡a
1
‡2
iso5218
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400
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0 |
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অ্যালেক্স টম্পসন
‡c
গবেষক
‡9
bn
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400
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Alex Thompson
‡c
researcher
‡9
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Alex Thompson
‡c
investigador
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es
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400
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Alex Thompson
‡c
ricercatore
‡9
it
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400
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Alex Thompson
‡c
wetenschapper
‡9
nl
|
670
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|
‡a
Author's A New Transgenic Mouse Model for the Study of Cell Cycle Control in Megakaryocytes
|
670
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|
|
‡a
Author's AINT/ERIC/TACC: an expanding family of proteins with C-terminal coiled coil domains.
|
670
|
|
|
‡a
Author's Analysis of HSC activity and compensatory Hox gene expression profile in Hoxb cluster mutant fetal liver cells
|
670
|
|
|
‡a
Author's c-Met inhibition in a HOXA9/Meis1 model of CN-AML.
|
670
|
|
|
‡a
Author's Characterization and localization of expression of an erythropoietin-induced gene, ERIC-1/TACC3, identified in erythroid precursor cells
|
670
|
|
|
‡a
Author's Complete array of HOX gene expression by RQ-PCR.
|
670
|
|
|
‡a
Author's Continuous MLL-ENL expression is necessary to establish a "Hox Code" and maintain immortalization of hematopoietic progenitor cells
|
670
|
|
|
‡a
Author's Correlation of TACC3, FGFR3, MMSET and p21 expression with the t(4;14)(p16.3;q32) in multiple myeloma
|
670
|
|
|
‡a
Author's Decitabine-Vorinostat combination treatment in acute myeloid leukemia activates pathways with potential for novel triple therapy
|
670
|
|
|
‡a
Author's Deregulated expression of c-myc in megakaryocytes of transgenic mice increases megakaryopoiesis and decreases polyploidization.
|
670
|
|
|
‡a
Author's Differential Hox expression in murine embryonic stem cell models of normal and malignant hematopoiesis.
|
670
|
|
|
‡a
Author's Effects of nitric oxide inhibition on systemic and renal hemodynamics in the hemorrhaged rat
|
670
|
|
|
‡a
Author's Endothelin receptor A blockade alters hemodynamic response to nitric oxide inhibition in rats
|
670
|
|
|
‡a
Author's Entinostat prevents leukemia maintenance in a collaborating oncogene-dependent model of cytogenetically normal acute myeloid leukemia
|
670
|
|
|
‡a
Author's Global down-regulation of HOX gene expression in PML-RARalpha + acute promyelocytic leukemia identified by small-array real-time PCR.
|
670
|
|
|
‡a
Author's Grappling with the HOX network in hematopoiesis and leukemia.
|
670
|
|
|
‡a
Author's High incidence of proviral integrations in the Hoxa locus in a new model of E2a-PBX1-induced B-cell leukemia.
|
670
|
|
|
‡a
Author's HOX genes in normal, engineered and malignant hematopoiesis
|
670
|
|
|
‡a
Author's Hoxa cluster genes determine the proliferative activity of adult mouse hematopoietic stem and progenitor cells.
|
670
|
|
|
‡a
Author's HoxA cluster is haploinsufficient for activity of hematopoietic stem and progenitor cells
|
670
|
|
|
‡a
Author's HOXA/PBX3 knockdown impairs growth and sensitizes cytogenetically normal acute myeloid leukemia cells to chemotherapy
|
670
|
|
|
‡a
Author's Hoxa6 potentiates short-term hemopoietic cell proliferation and extended self-renewal.
|
670
|
|
|
‡a
Author's Hoxa9 collaborates with E2A-PBX1 in mouse B cell leukemia in association with Flt3 activation and decrease of B cell gene expression
|
670
|
|
|
‡a
Author's Inhibition of HOX/PBX dimer formation leads to necroptosis in acute myeloid leukemia cells
|
670
|
|
|
‡a
Author's Integrated analysis of the molecular action of Vorinostat identifies epi-sensitised targets for combination therapy.
|
670
|
|
|
‡a
Author's Low-dose salinomycin induces anti-leukemic responses in AML and MLL.
|
670
|
|
|
‡a
Author's Molecular dissection of Meis1 reveals 2 domains required for leukemia induction and a key role for Hoxa gene activation
|
670
|
|
|
‡a
Author's Overexpression of cyclin D1 moderately increases ploidy in megakaryocytes
|
670
|
|
|
‡a
Author's POU2F1 activity regulates HOXD10 and HOXD11 promoting a proliferative and invasive phenotype in head and neck cancer
|
670
|
|
|
‡a
Author's Prolonged molecular remission in PML-RARalpha-positive acute promyelocytic leukemia treated with minimal chemotherapy followed by maintenance including the histone deacetylase inhibitor sodium valproate
|
670
|
|
|
‡a
Author's Protein arginine-methyltransferase-dependent oncogenesis
|
670
|
|
|
‡a
Author's Quantification of Hox and surfactant protein-B transcription during murine lung development.
|
670
|
|
|
‡a
Author's Rational drug repurposing using sscMap analysis in a HOX-TALE model of leukemia.
|
670
|
|
|
‡a
Author's Repression of A TAF
|
670
|
|
|
‡a
Author's Repression of A TAF(II)32 isoform as part of a program of genes regulated during mpl ligand-induced megakaryocyte differentiation
|
670
|
|
|
‡a
Author's Signaling by the Mpl receptor involves IKK and NF-kappaB.
|
670
|
|
|
‡a
Author's Stroma-free hemoglobin increases blood pressure and GFR in the hypotensive rat: role of nitric oxide
|
670
|
|
|
‡a
Author's Targeted deletion of the Hoxa cluster affects B lymphopoiesis through depletion of early lymphoid progenitors.
|
670
|
|
|
‡a
Author's The histone deacetylase inhibitor Romidepsin induces as a cascade of differential gene expression and altered histone H3K9 marks in myeloid leukaemia cells
|
670
|
|
|
‡a
Author's The pathophysiology of HOX genes and their role in cancer.
|
670
|
|
|
‡a
Author's Three-dimensional ex vivo co-culture models of the leukaemic bone marrow niche for functional drug testing
|
670
|
|
|
‡a
Author's Thrombopoietin, flt3-ligand and c-kit-ligand modulate HOX gene expression in expanding cord blood CD133 cells
|
670
|
|
|
‡a
Author's Variable expression and silencing of CRISPR-Cas9 targeted transgenes identifies the AAVS1 locus as not an entirely safe harbour
|
909
|
|
|
‡a
(orcid) 0000000293155321
‡9
1
|
919
|
|
|
‡a
pou2f1activityregulateshoxd10andhoxd11promotingaproliferativeandinvasivephenotypeinheadandneckcancer
‡A
POU2F1 activity regulates HOXD10 and HOXD11 promoting a proliferative and invasive phenotype in head and neck cancer
‡9
1
|
919
|
|
|
‡a
overexpressionofcyclind1moderatelyincreasesploidyinmegakaryocytes
‡A
Overexpression of cyclin D1 moderately increases ploidy in megakaryocytes
‡9
1
|
919
|
|
|
‡a
moleculardissectionofmeis1reveals2domainsrequiredforleukemiainductionandakeyroleforhoxageneactivation
‡A
Molecular dissection of Meis1 reveals 2 domains required for leukemia induction and a key role for Hoxa gene activation
‡9
1
|
919
|
|
|
‡a
lowdosesalinomycininducesantileukemicresponsesinamlandmll
‡A
Low-dose salinomycin induces anti-leukemic responses in AML and MLL.
‡9
1
|
919
|
|
|
‡a
integratedanalysisofthemolecularactionofvorinostatidentifiesepisensitisedtargetsforcombinationtherapy
‡A
Integrated analysis of the molecular action of Vorinostat identifies epi-sensitised targets for combination therapy.
‡9
1
|
919
|
|
|
‡a
inhibitionofhoxpbxdimerformationleadstonecroptosisinacutemyeloidleukemiacells
‡A
Inhibition of HOX/PBX dimer formation leads to necroptosis in acute myeloid leukemia cells
‡9
1
|
919
|
|
|
‡a
hoxa9collaborateswithe2apbx1inmousebcellleukemiainassociationwithflt3activationanddecreaseofbcellgeneexpression
‡A
Hoxa9 collaborates with E2A-PBX1 in mouse B cell leukemia in association with Flt3 activation and decrease of B cell gene expression
‡9
1
|
919
|
|
|
‡a
hoxa6potentiatesshorttermhemopoieticcellproliferationandextendedselfrenewal
‡A
Hoxa6 potentiates short-term hemopoietic cell proliferation and extended self-renewal.
‡9
1
|
919
|
|
|
‡a
hoxapbx3knockdownimpairsgrowthandsensitizescytogeneticallynormalacutemyeloidleukemiacellstochemotherapy
‡A
HOXA/PBX3 knockdown impairs growth and sensitizes cytogenetically normal acute myeloid leukemia cells to chemotherapy
‡9
1
|
919
|
|
|
‡a
hoxaclusterishaploinsufficientforactivityofhematopoieticstemandprogenitorcells
‡A
HoxA cluster is haploinsufficient for activity of hematopoietic stem and progenitor cells
‡9
1
|
919
|
|
|
‡a
hoxaclustergenesdeterminetheproliferativeactivityofadultmousehematopoieticstemandprogenitorcells
‡A
Hoxa cluster genes determine the proliferative activity of adult mouse hematopoietic stem and progenitor cells.
‡9
1
|
919
|
|
|
‡a
hoxgenesinnormalengineeredandmalignanthematopoiesis
‡A
HOX genes in normal, engineered and malignant hematopoiesis
‡9
1
|
919
|
|
|
‡a
highincidenceofproviralintegrationsinthehoxalocusinanewmodelofe2apbx1inducedbcellleukemia
‡A
High incidence of proviral integrations in the Hoxa locus in a new model of E2a-PBX1-induced B-cell leukemia.
‡9
1
|
919
|
|
|
‡a
grapplingwiththehoxnetworkinhematopoiesisandleukemia
‡A
Grappling with the HOX network in hematopoiesis and leukemia.
‡9
1
|
919
|
|
|
‡a
globaldownregulationofhoxgeneexpressioninpmlraralpha+acutepromyelocyticleukemiaidentifiedbysmallarrayrealtimepcr
‡A
Global down-regulation of HOX gene expression in PML-RARalpha + acute promyelocytic leukemia identified by small-array real-time PCR.
‡9
1
|
919
|
|
|
‡a
entinostatpreventsleukemiamaintenanceinacollaboratingoncogenedependentmodelofcytogeneticallynormalacutemyeloidleukemia
‡A
Entinostat prevents leukemia maintenance in a collaborating oncogene-dependent model of cytogenetically normal acute myeloid leukemia
‡9
1
|
919
|
|
|
‡a
endothelinreceptorablockadealtershemodynamicresponsetonitricoxideinhibitioninrats
‡A
Endothelin receptor A blockade alters hemodynamic response to nitric oxide inhibition in rats
‡9
1
|
919
|
|
|
‡a
effectsofnitricoxideinhibitiononsystemicandrenalhemodynamicsinthehemorrhagedrat
‡A
Effects of nitric oxide inhibition on systemic and renal hemodynamics in the hemorrhaged rat
‡9
1
|
919
|
|
|
‡a
differentialhoxexpressioninmurineembryonicstemcellmodelsofnormalandmalignanthematopoiesis
‡A
Differential Hox expression in murine embryonic stem cell models of normal and malignant hematopoiesis.
‡9
1
|
919
|
|
|
‡a
deregulatedexpressionof100mycinmegakaryocytesoftransgenicmiceincreasesmegakaryopoiesisanddecreasespolyploidization
‡A
Deregulated expression of c-myc in megakaryocytes of transgenic mice increases megakaryopoiesis and decreases polyploidization.
‡9
1
|
919
|
|
|
‡a
decitabinevorinostatcombinationtreatmentinacutemyeloidleukemiaactivatespathwayswithpotentialfornoveltripletherapy
‡A
Decitabine-Vorinostat combination treatment in acute myeloid leukemia activates pathways with potential for novel triple therapy
‡9
1
|
919
|
|
|
‡a
correlationoftacc3fgfr3mmsetandp21expressionwiththet414p163q32inmultiplemyeloma
‡A
Correlation of TACC3, FGFR3, MMSET and p21 expression with the t(4;14)(p16.3;q32) in multiple myeloma
‡9
1
|
919
|
|
|
‡a
continuousmllenlexpressionisnecessarytoestablishahoxcodeandmaintainimmortalizationofhematopoieticprogenitorcells
‡A
Continuous MLL-ENL expression is necessary to establish a "Hox Code" and maintain immortalization of hematopoietic progenitor cells
‡9
1
|
919
|
|
|
‡a
completearrayofhoxgeneexpressionbyrqpcr
‡A
Complete array of HOX gene expression by RQ-PCR.
‡9
1
|
919
|
|
|
‡a
characterizationandlocalizationofexpressionofanerythropoietininducedgeneeric1tacc3identifiedinerythroidprecursorcells
‡A
Characterization and localization of expression of an erythropoietin-induced gene, ERIC-1/TACC3, identified in erythroid precursor cells
‡9
1
|
919
|
|
|
‡a
100metinhibitioninahoxa9meis1modelofcnaml
‡A
c-Met inhibition in a HOXA9/Meis1 model of CN-AML.
‡9
1
|
919
|
|
|
‡a
analysisofhscactivityandcompensatoryhoxgeneexpressionprofileinhoxbclustermutantfetallivercells
‡A
Analysis of HSC activity and compensatory Hox gene expression profile in Hoxb cluster mutant fetal liver cells
‡9
1
|
919
|
|
|
‡a
ainterictaccanexpandingfamilyofproteinswith100terminalcoiledcoildomains
‡A
AINT/ERIC/TACC: an expanding family of proteins with C-terminal coiled coil domains.
‡9
1
|
919
|
|
|
‡a
newtransgenicmousemodelforthestudyofcellcyclecontrolinmegakaryocytes
‡A
A New Transgenic Mouse Model for the Study of Cell Cycle Control in Megakaryocytes
‡9
1
|
919
|
|
|
‡a
variableexpressionandsilencingofcrisprcas9targetedtransgenesidentifiestheaavs1locusasnotanentirelysafeharbour
‡A
Variable expression and silencing of CRISPR-Cas9 targeted transgenes identifies the AAVS1 locus as not an entirely safe harbour
‡9
1
|
919
|
|
|
‡a
thrombopoietinflt3ligandand100kitligandmodulatehoxgeneexpressioninexpandingcordbloodcd133cells
‡A
Thrombopoietin, flt3-ligand and c-kit-ligand modulate HOX gene expression in expanding cord blood CD133 cells
‡9
1
|
919
|
|
|
‡a
3dimensionalexvivococulturemodelsoftheleukaemicbonemarrownicheforfunctionaldrugtesting
‡A
Three-dimensional ex vivo co-culture models of the leukaemic bone marrow niche for functional drug testing
‡9
1
|
919
|
|
|
‡a
pathophysiologyofhoxgenesandtheirroleincancer
‡A
The pathophysiology of HOX genes and their role in cancer.
‡9
1
|
919
|
|
|
‡a
histonedeacetylaseinhibitorromidepsininducesasacascadeofdifferentialgeneexpressionandalteredhistoneh3k9marksinmyeloidleukaemiacells
‡A
The histone deacetylase inhibitor Romidepsin induces as a cascade of differential gene expression and altered histone H3K9 marks in myeloid leukaemia cells
‡9
1
|
919
|
|
|
‡a
targeteddeletionofthehoxaclusteraffectsblymphopoiesisthroughdepletionofearlylymphoidprogenitors
‡A
Targeted deletion of the Hoxa cluster affects B lymphopoiesis through depletion of early lymphoid progenitors.
‡9
1
|
919
|
|
|
‡a
stromafreehemoglobinincreasesbloodpressureandgfrinthehypotensiveratroleofnitricoxide
‡A
Stroma-free hemoglobin increases blood pressure and GFR in the hypotensive rat: role of nitric oxide
‡9
1
|
919
|
|
|
‡a
signalingbythemplreceptorinvolvesikkandnfkappab
‡A
Signaling by the Mpl receptor involves IKK and NF-kappaB.
‡9
1
|
919
|
|
|
‡a
repressionofataf232isoformaspartofaprogramofgenesregulatedduringmplligandinducedmegakaryocytedifferentiation
‡A
Repression of A TAF(II)32 isoform as part of a program of genes regulated during mpl ligand-induced megakaryocyte differentiation
‡9
1
|
919
|
|
|
‡a
repressionofataf
‡A
Repression of A TAF
‡9
1
|
919
|
|
|
‡a
rationaldrugrepurposingusingsscmapanalysisinahoxtalemodelofleukemia
‡A
Rational drug repurposing using sscMap analysis in a HOX-TALE model of leukemia.
‡9
1
|
919
|
|
|
‡a
quantificationofhoxandsurfactantproteinbtranscriptionduringmurinelungdevelopment
‡A
Quantification of Hox and surfactant protein-B transcription during murine lung development.
‡9
1
|
919
|
|
|
‡a
proteinargininemethyltransferasedependentoncogenesis
‡A
Protein arginine-methyltransferase-dependent oncogenesis
‡9
1
|
919
|
|
|
‡a
prolongedmolecularremissioninpmlraralphapositiveacutepromyelocyticleukemiatreatedwithminimalchemotherapyfollowedbymaintenanceincludingthehistonedeacetylaseinhibitorsodiumvalproate
‡A
Prolonged molecular remission in PML-RARalpha-positive acute promyelocytic leukemia treated with minimal chemotherapy followed by maintenance including the histone deacetylase inhibitor sodium valproate
‡9
1
|
946
|
|
|
‡a
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1
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996
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