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WKP|Q47812749
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20241221010719.0 |
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(WKP)Q47812749
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0000-0002-7519-3279
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orcid
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(OCoLC)Q47812749
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19000000
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Stefan Rose-John
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researcher
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1
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iso5218
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Stefan Rose-John
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wetenschapper
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nl
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Stefan Rose-John
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hulumtues
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Stefan Rose-John
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deutscher Biochemiker und Hochschullehrer
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de
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670
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Author's 1H, 15N and 13C backbone assignment of the carboxyl terminal domain of the cytokine binding module of the interleukin-6 receptor.
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670
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Author's A bioactive designer cytokine for human hematopoietic progenitor cell expansion
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670
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Author's A designer hyper interleukin 11 (H11) is a biologically active cytokine.
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670
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Author's A disintegrin and metalloprotease 10
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670
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Author's A disintegrin and metalloprotease 10 (ADAM10) is a central regulator of murine liver tissue homeostasis
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670
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Author's A disintegrin and metalloprotease 17 dynamic interaction sequence, the sweet tooth for the human interleukin 6 receptor
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670
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Author's A disintegrin and metalloprotease (ADAM) 10 and ADAM17 are major sheddases of T cell immunoglobulin and mucin domain 3 (Tim-3)
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670
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Author's A key role for gp130 expressed on peripheral sensory nerves in pathological pain.
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670
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Author's A metalloprotease inhibitor blocks shedding of the IL-6 receptor and the p60 TNF receptor
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670
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Author's A new hepatocyte stimulating factor: cardiotrophin-1
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670
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Author's A new hepatocyte stimulating factor: cardiotrophin-1 (CT-1)
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670
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Author's A new multiple trauma model of the mouse
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670
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Author's A New Type of Cytokine Receptor Antagonist Directly Targeting gp130
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670
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Author's A non-conservative polymorphism in the IL-6 signal transducer
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670
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Author's A non-conservative polymorphism in the IL-6 signal transducer (IL6ST)/gp130 is associated with myocardial infarction in a hypertensive population
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670
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Author's A novel bispecific single-chain antibody for ADAM17 and CD3 induces T-cell-mediated lysis of prostate cancer cells
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670
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Author's A Novel Small-Molecule Inhibitor Targeting the IL-6 Receptor β Subunit, Glycoprotein 130.
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670
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Author's A role for IL-27p28 as an antagonist of gp130-mediated signaling
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670
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Author's A role for the immunoglobulin-like domain of the human IL-6 receptor. Intracellular protein transport and shedding
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670
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Author's A soluble form of the interleukin-6 family signal transducer gp130 is dimerized via a C-terminal disulfide bridge resulting from alternative mRNA splicing.
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670
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Author's A switch from white to brown fat increases energy expenditure in cancer-associated cachexia
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670
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Author's A variant in IL6ST with a selective IL-11 signaling defect in human and mouse
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670
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Author's Abrogation of viral interleukin-6
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670
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Author's Abrogation of viral interleukin-6 (vIL-6)-induced signaling by intracellular retention and neutralization of vIL-6 with an anti-vIL-6 single-chain antibody selected by phage display
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670
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Author's Accurate variant detection across non-amplified and whole genome amplified DNA using targeted next generation sequencing
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670
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Author's "Activated" STAT proteins: a paradoxical consequence of inhibited JAK-STAT signaling in cytomegalovirus-infected cells
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670
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Author's Activation of gp 130 by IL-6/soluble IL-6 receptor induces neuronal differentiation
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670
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Author's Activation of interleukin-6-induced glycoprotein 130/signal transducer and activator of transcription 3 pathway in mesenchymal stem cells enhances hepatic differentiation, proliferation, and liver regeneration
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670
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Author's Activation of liver X receptors inhibits experimental fibrosis by interfering with interleukin-6 release from macrophages
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670
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Author's Activation of the anti-inflammatory reflex blocks lipopolysaccharide-induced decrease in synaptic inhibition in the temporal cortex of the rat.
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670
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Author's Acute-phase response factor, increased binding, and target gene transcription during liver regeneration.
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670
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Author's ADAM-Mediated Signalling Pathways in Gastrointestinal Cancer Formation
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670
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Author's ADAM10 and ADAM17 have opposite roles during sprouting angiogenesis
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670
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Author's ADAM10 inhibition of human CD30 shedding increases specificity of targeted immunotherapy in vitro
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670
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Author's ADAM17: a molecular switch to control inflammation and tissue regeneration
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670
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Author's ADAM17 controls IL-6 signaling by cleavage of the murine IL-6Rα from the cell surface of leukocytes during inflammatory responses
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670
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Author's Adam17 Deficiency Promotes Atherosclerosis by Enhanced TNFR2 Signaling in Mice
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670
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Author's ADAM17 is a survival factor for microglial cells in vitro and in vivo after spinal cord injury in mice.
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670
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Author's ADAM17 is required for EGF-R-induced intestinal tumors via IL-6 trans-signaling.
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670
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Author's ADAM17-mediated shedding of the IL6R induces cleavage of the membrane stub by gamma-secretase
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670
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Author's ADAM17-overexpressing breast cancer cells selectively targeted by antibody-toxin conjugates
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670
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Author's ADAM17, shedding, TACE as therapeutic targets
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670
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Author's ADAM17 substrate release in proximal tubule drives kidney fibrosis
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670
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Author's Allergen-induced IL-6 trans-signaling activates γδ T cells to promote type 2 and type 17 airway inflammation.
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670
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Author's ALTERED PULMONARY INTERLEUKIN-6 SIGNALING IN PRETERM INFANTS DEVELOPING BRONCHOPULMONARY DYSPLASIA
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670
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Author's Alternative assay procedures for cytokines and soluble receptors of the IL-6 family
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670
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Author's An analysis of the function and expression of D6 on lymphatic endothelial cells
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670
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Author's An evaluation of 2,5-norbornadiene as a reversible inhibitor of ethylene action in deepwater rice
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670
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Author's AN IL-6/IL-6 SOLUBLE RECEPTOR
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670
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Author's AN IL-6/IL-6 SOLUBLE RECEPTOR (IL-6R) HYBRID PROTEIN (H-IL-6) INDUCES EPO-INDEPENDENT ERYTHROID DIFFERENTIATION IN HUMAN CD34+CELLS
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670
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Author's An interleukin-6 receptor-dependent molecular switch mediates signal transduction of the IL-27 cytokine subunit p28 (IL-30) via a gp130 protein receptor homodimer
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670
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Author's Analysis of IL-6/gp130 family receptor expression reveals that in contrast to astroglia, microglia lack the oncostatin M receptor and functional responses to oncostatin M
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670
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Author's Analysis of the leukemia inhibitory factor receptor functional domains by chimeric receptors and cytokines
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670
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Author's Antibodies against tumor necrosis factor
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670
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Author's Antibodies against tumor necrosis factor (TNF) induce T-cell apoptosis in patients with inflammatory bowel diseases via TNF receptor 2 and intestinal CD14⁺ macrophages.
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670
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Author's Apoptosis is a natural stimulus of IL6R shedding and contributes to the proinflammatory trans-signaling function of neutrophils
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670
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Author's Astrocytic alterations in interleukin-6/Soluble interleukin-6 receptor alpha double-transgenic mice
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670
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Author's Ataxin-10, the spinocerebellar ataxia type 10 neurodegenerative disorder protein, is essential for survival of cerebellar neurons
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670
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Author's Batf-dependent Th17 cells critically regulate IL-23 driven colitis-associated colon cancer.
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670
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Author's Biosynthesis and distribution of leucocyte elastase inhibitor. Production of recombinant inhibitor.
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670
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Author's Biosynthesis and half-life of the interleukin-6 receptor and its signal transducer gp130.
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670
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Author's Blockade of interleukin 6 trans signaling suppresses T-cell resistanceagainst apoptosis in chronic intestinal inflammation: Evidence in Crohn diseaseand experimental colitis in vivo
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670
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Author's Blocking IL-6 trans-signaling prevents high-fat diet-induced adipose tissue macrophage recruitment but does not improve insulin resistance
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670
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Author's Bryostatin 1, an activator of protein kinase C, mimics as well as inhibits biological effects of the phorbol ester TPA in vivo and in vitro
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670
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Author's Cancer-associated mutations in the canonical cleavage site do not influence CD99 shedding by the metalloprotease meprin β but alter cell migration in vitro
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670
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Author's CDP-870. Celltech/Pfizer.
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670
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Author's Cell-type-restricted anti-cytokine therapy: TNF inhibition from one pathogenic source
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670
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Author's Cellular cholesterol depletion triggers shedding of the human interleukin-6 receptor by ADAM10 and ADAM17 (TACE)
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670
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Author's Cellular senescence or EGFR signaling induces Interleukin 6
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670
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Author's Cellular senescence or EGFR signaling induces Interleukin 6 (IL-6) receptor expression controlled by mammalian target of rapamycin (mTOR).
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670
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Author's Ciliary neurotrophic factor induces acute-phase protein expression in hepatocytes
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670
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Author's Circulating Soluble IL-6R but Not ADAM17 Activation Drives Mononuclear Cell Migration in Tissue Inflammation
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670
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Author's Classic IL-6R signalling is dispensable for intestinal epithelial proliferation and repair
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670
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Author's Classic interleukin-6 receptor signaling and interleukin-6 trans-signaling differentially control angiotensin II-dependent hypertension, cardiac signal transducer and activator of transcription-3 activation, and vascular hypertrophy in vivo
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670
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Author's Cleavage Site Localization Differentially Controls Interleukin-6 Receptor Proteolysis by ADAM10 and ADAM17.
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670
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Author's CNTF reverses obesity-induced insulin resistance by activating skeletal muscle AMPK.
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670
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Author's Coexpression of IL-6 and soluble IL-6R causes nodular regenerative hyperplasia and adenomas of the liver.
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670
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Author's Combined interleukin 6 and soluble interleukin 6 receptor accelerates murine liver regeneration
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670
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Author's Complex of soluble human IL-6-receptor/IL-6 up-regulates expression of acute-phase proteins
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670
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Author's Conservation of IL-6 trans-signaling mechanisms controlling L-selectin adhesion by fever-range thermal stress
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670
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Author's Constitutive gp130 activation rapidly accelerates the transformation of human hepatocytes via an impaired oxidative stress response
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670
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Author's Constitutively active mutant gp130 receptor protein from inflammatory hepatocellular adenoma is inhibited by an anti-gp130 antibody that specifically neutralizes interleukin 11 signaling
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670
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Author's Contribution of vascular cell-derived cytokines to innate and inflammatory pathways in atherogenesis
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670
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Author's Coordination of interleukin-6 biology by membrane bound and soluble receptors
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670
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Author's Corrigendum: Trans-presentation of IL-6 by dendritic cells is required for the priming of pathogenic TH17 cells
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670
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Author's Critical role of the disintegrin metalloprotease ADAM17 for intestinal inflammation and regeneration in mice
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670
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Author's Cutting Edge: Trans-Signaling via the Soluble IL-6R Abrogates the Induction of FoxP3 in Naive CD4+CD25- T Cells
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670
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Author's Cytokines as therapeutic drugs
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670
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Author's Cytokines come of age.
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670
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Author's d(GGGT) 4 and r(GGGU) 4 are both HIV-1 inhibitors and interleukin-6 receptor aptamers
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670
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Author's Delivery of hyper-interleukin-6 to the injured spinal cord increases neutrophil and macrophage infiltration and inhibits axonal growth
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670
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Author's Dendritic cell development requires histone deacetylase activity
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670
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Author's Dendritic cell lineage commitment is instructed by distinct cytokine signals
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670
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Author's Designer cytokines for human haematopoietic progenitor cell expansion: impact for tissue regeneration.
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670
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Author's Designing cytokine variants by phage-display
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670
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Author's Development of a human interleukin-6 receptor antagonist.
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670
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Author's Development of a monoclonal antibody-based enzyme-linked immunoabsorbent assay for the binding of gp130 to the IL-6/IL-6R complex and its competitive inhibition
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670
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Author's Development of an interleukin (IL) 6 receptor antagonist that inhibits IL-6-dependent growth of human myeloma cells.
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670
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Author's Devic disease: Translational medicine at work
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670
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Author's Different Soluble Forms of the Interleukin-6 Family Signal Transducer gp130 Fine-tune the Blockade of Interleukin-6 Trans-signaling
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670
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Author's Differential effects of phorbol esters on c-fos and c-myc and ornithine decarboxylase gene expression in mouse skin in vivo.
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670
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Author's Differential expression of CD126 and CD130 mediates different STAT-3 phosphorylation in CD4+CD25- and CD25high regulatory T cells.
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670
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Author's Differential response of neuronal cells to a fusion protein of ciliary neurotrophic factor/soluble CNTF-receptor and leukemia inhibitory factor
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670
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Author's Differential shedding of the two subunits of the interleukin-6 receptor
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670
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Author's Differentially regulated GPVI ectodomain shedding by multiple platelet-expressed proteinases.
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670
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Author's Direct determination of the interleukin-6 binding epitope of the interleukin-6 receptor by NMR spectroscopy
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670
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Author's Dissecting Interleukin-6 Classic- and Trans-Signaling in Inflammation and Cancer
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670
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Author's Distinct Effects of IL-6 Classic and Trans-Signaling in Bone Fracture Healing
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670
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Author's Distinct role of gp130 activation in promoting self-renewal divisions by mitogenically stimulated murine hematopoietic stem cells
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670
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Author's Diverse cell surface protein ectodomains are shed by a system sensitive to metalloprotease inhibitors.
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670
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Author's Due to interleukin-6 type cytokine redundancy only glycoprotein 130 receptor blockade efficiently inhibits myeloma growth
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670
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Author's Dynamics of the gp130 cytokine complex: a model for assembly on the cellular membrane
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670
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Author's Early hepatocyte DNA synthetic response posthepatectomy is modulated by IL-6 trans-signaling and PI3K/AKT activation
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670
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Author's Effect of Soluble Interleukin-6 Receptor on Interleukin-6 Synthesis in Human Skin Fibroblasts
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670
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Author's Effect of submergence on the cell wall composition of deep-water rice internodes
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670
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Author's Effects of blockade of peripheral interleukin-6 trans-signaling on hippocampus-dependent and independent memory in mice
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670
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Author's Efficient retrovirus-mediated gene transfer to transplantable human bone marrow cells in the absence of fibronectin.
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670
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Author's EGFR in Tumor-Associated Myeloid Cells Promotes Development of Colorectal Cancer in Mice and Associates With Outcomes of Patients
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670
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Author's Elastin-like polypeptides revolutionize recombinant protein expression and their biomedical application
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670
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Author's ELPylated anti-human TNF therapeutic single-domain antibodies for prevention of lethal septic shock.
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670
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Author's Enhancing influence of intranasal interleukin-6 on slow-wave activity and memory consolidation during sleep
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670
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Author's Enzymatically Degraded, Nonoxidized LDL Induces Human Vascular Smooth Muscle Cell Activation, Foam Cell Transformation, and Proliferation
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670
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Author's Erratum: STAT3 regulated ARF expression suppresses prostate cancer metastasis
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670
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Author's Essential role of neutrophil mobilization in concanavalin A-induced hepatitis is based on classic IL-6 signaling but not on IL-6 trans-signaling
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670
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Author's Essential roles of IL-6 trans-signaling in colonic epithelial cells, induced by the IL-6/soluble-IL-6 receptor derived from lamina propria macrophages, on the development of colitis-associated premalignant cancer in a murine model
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670
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Author's Expression of a biologically active murine tissue inhibitor of metalloproteinases-1
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670
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Author's Expression of a biologically active murine tissue inhibitor of metalloproteinases-1 (TIMP-1) in baculovirus-infected insect cells. Purification and tissue distribution in the rat.
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670
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Author's Expression of the kinase domain of mouse protein kinase C in E. coli.
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670
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Author's Extramedullary expansion of hematopoietic progenitor cells in interleukin
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670
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Author's Extramedullary expansion of hematopoietic progenitor cells in interleukin (IL)-6-sIL-6R double transgenic mice
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670
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Author's Factor XII-Driven Inflammatory Reactions with Implications for Anaphylaxis
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670
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Author's “Family reunion” – A structured view on the composition of the receptor complexes of interleukin-6-type and interleukin-12-type cytokines
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670
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Author's Fast modulation of heat-activated ionic current by proinflammatory interleukin 6 in rat sensory neurons
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670
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Author's Fever-range thermal stress promotes lymphocyte trafficking across high endothelial venules via an interleukin 6 trans-signaling mechanism.
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670
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Author's Forced dimerization of gp130 leads to constitutive STAT3 activation, cytokine-independent growth, and blockade of differentiation of embryonic stem cells
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670
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Author's Forced homo- and heterodimerization of all gp130-type receptor complexes leads to constitutive ligand-independent signaling and cytokine-independent growth
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670
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Author's Frontline Science: Proliferation of Ly6C(+) monocytes during urinary tract infections is regulated by IL-6 trans-signaling
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670
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Author's Functional characterization of a soluble gp130 isoform and its therapeutic capacity in an experimental model of inflammatory arthritis
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670
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Author's Functional Characterization of Colon Cancer-Associated Mutations in ADAM17: Modifications in the Pro-Domain Interfere with Trafficking and Maturation
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670
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Author's Functional Characterization of Colon-Cancer-Associated Variants in ADAM17 Affecting the Catalytic Domain
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670
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Author's Functional distinction of two regions of human interleukin 6 important for signal transduction via gp130.
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670
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Author's Functional expression of a biologically active fragment of soluble gp130 as an ELP-fusion protein in transgenic plants: purification via inverse transition cycling
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670
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Author's G protein-coupled receptor 43 is essential for neutrophil recruitment during intestinal inflammation
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670
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Author's Generation and function of the soluble interleukin-6 receptor.
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670
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Author's Generation of tumor-reactive CTL against the tumor-associated antigen HER2 using retrovirally transduced dendritic cells derived from CD34+ hemopoietic progenitor cells.
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670
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Author's Genetic manipulations utilizing albumin and alpha-fetoprotein promoter/enhancers affect both hepatocytes and oval cells
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670
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Author's Genetic partitioning of interleukin-6 signalling in mice dissociates Stat3 from Smad3-mediated lung fibrosis
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670
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Author's Genetically modified tumour vaccines
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670
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Author's Genetically modified tumour vaccines (GMTV) in melanoma clinical trials
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670
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Author's Glycoprotein 130 receptor signaling mediates α-cell dysfunction in a rodent model of type 2 diabetes.
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670
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Author's GP130 activation induces myeloma and collaborates with MYC.
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670
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Author's gp130 activation is regulated by D2-D3 interdomain connectivity.
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670
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Author's gp130 dimerization in the absence of ligand: preformed cytokine receptor complexes
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670
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Author's Gp130-Signaling synergizes with FL and TPO for the long-term expansion of cord blood progenitors
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670
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Author's gp130-stimulating designer cytokine Hyper-interleukin-6 synergizes with murine stroma for long-term survival of primitive human hematopoietic progenitor cells.
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670
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Author's GP130 stimulation and the maintenance of stem cells
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670
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Author's Hepatocellular hyperplasia, plasmacytoma formation, and extramedullary hematopoiesis in interleukin (IL)-6/soluble IL-6 receptor double-transgenic mice
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670
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Author's Hepatocytes contribute to immune regulation in the liver by activation of the Notch signaling pathway in T cells.
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670
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Author's HHV-8-encoded viral IL-6 collaborates with mouse IL-6 in the development of multicentric Castleman disease in mice
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670
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Author's Hitting a complex target: an update on interleukin-6 trans-signalling
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670
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Author's Human CNTF and related cytokines: effects on DRG neurone survival
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670
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Author's Human herpes virus 8 interleukin-6 homologue triggers gp130 on neuronal and hematopoietic cells
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670
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|
‡a
Author's Human herpesvirus 8-derived viral IL-6 induces PTX3 expression in Kaposi's sarcoma cells
|
|
670
|
|
|
‡a
Author's Human interleukin-6 facilitates hepatitis B virus infection in vitro and in vivo.
|
|
670
|
|
|
‡a
Author's Human TYK2 deficiency: Mycobacterial and viral infections without hyper-IgE syndrome
|
|
670
|
|
|
‡a
Author's Humoral responses to melanoma vaccine, genetically modified with interleukin 6 and soluble interleukin 6 receptor
|
|
670
|
|
|
‡a
Author's Hyper-IL-6 gene therapy reverses fulminant hepatic failure.
|
|
670
|
|
|
‡a
Author's Identification of a region within the cytoplasmic domain of the interleukin-6
|
|
670
|
|
|
‡a
Author's Identification of a region within the cytoplasmic domain of the interleukin-6 (IL-6) signal transducer gp130 important for ligand-induced endocytosis of the IL-6 receptor
|
|
670
|
|
|
‡a
Author's Identification of canonical tyrosine-dependent and non-canonical tyrosine-independent STAT3 activation sites in the intracellular domain of the interleukin 23 receptor
|
|
670
|
|
|
‡a
Author's Identification of Predictive Biomarkers for Cytokine Release Syndrome after Chimeric Antigen Receptor T-cell Therapy for Acute Lymphoblastic Leukemia
|
|
670
|
|
|
‡a
Author's Identification of residues in the putative 5th helical region of human interleukin-6, important for activation of the IL-6 signal transducer, gp130.
|
|
670
|
|
|
‡a
Author's Identification of Single Amino Acid Residues of Human IL-6 Involved in Receptor Binding and Signal Initiation
|
|
670
|
|
|
‡a
Author's Identification of two novel regions of human IL-6 responsible for receptor binding and signal transduction.
|
|
670
|
|
|
‡a
Author's IL-10-induced gp130 expression in mouse mast cells permits IL-6 trans-signaling
|
|
670
|
|
|
‡a
Author's IL-6 and Its Soluble Receptor Orchestrate a Temporal Switch in the Pattern of Leukocyte Recruitment Seen during Acute Inflammation
|
|
670
|
|
|
‡a
Author's IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer
|
|
670
|
|
|
‡a
Author's IL-6 biology: implications for clinical targeting in rheumatic disease
|
|
670
|
|
|
‡a
Author's IL-6 blockade by monoclonal antibodies inhibits apolipoprotein (a) expression and lipoprotein (a) synthesis in humans
|
|
670
|
|
|
‡a
Author's IL-6 controls the innate immune response against Listeria monocytogenes via classical IL-6 signaling
|
|
670
|
|
|
‡a
Author's IL-6/IL-6R axis plays a critical role in acute kidney injury
|
|
670
|
|
|
‡a
Author's IL-6 Improves Energy and Glucose Homeostasis in Obesity via Enhanced Central IL-6 trans-Signaling
|
|
670
|
|
|
‡a
Author's IL-6 pathway in the liver: From physiopathology to therapy
|
|
670
|
|
|
‡a
Author's IL-6 Receptor Independent Stimulation of Human gp130 by Viral IL-6
|
|
670
|
|
|
‡a
Author's IL-6 regulates MCP-1, ICAM-1 and IL-6 expression in human myoblasts
|
|
670
|
|
|
‡a
Author's IL-6 regulates neutrophil microabscess formation in IL-17A-driven psoriasiform lesions
|
|
670
|
|
|
‡a
Author's IL-6 signaling promotes tumor growth in colorectal cancer
|
|
670
|
|
|
‡a
Author's IL-6 trans-signaling-dependent rapid development of cytotoxic CD8+ T cell function
|
|
670
|
|
|
‡a
Author's IL-6 Trans-Signaling Drives Murine Crescentic GN
|
|
670
|
|
|
‡a
Author's IL-6 trans-signaling in formation and progression of malignant ascites in ovarian cancer
|
|
670
|
|
|
‡a
Author's IL-6 Trans-Signaling in the Brain Influences the Metabolic Phenotype of the 3xTg-AD Mouse Model of Alzheimer's Disease
|
|
670
|
|
|
‡a
Author's IL-6 trans-signaling is essential for the development of hepatocellular carcinoma in mice
|
|
670
|
|
|
‡a
Author's IL-6 trans-signaling licenses mouse and human tumor microvascular gateways for trafficking of cytotoxic T cells
|
|
670
|
|
|
‡a
Author's IL-6 trans-signaling modulates TLR4-dependent inflammatory responses via STAT3.
|
|
670
|
|
|
‡a
Author's IL-6 trans-signaling promotes pancreatitis-associated lung injury and lethality
|
|
670
|
|
|
‡a
Author's IL-6 trans-signaling: the heat is on.
|
|
670
|
|
|
‡a
Author's IL-6 trans-signaling via the soluble IL-6 receptor: importance for the pro-inflammatory activities of IL-6.
|
|
670
|
|
|
‡a
Author's IL-6-trans-signalling increases rapid-eye-movement sleep in rats
|
|
670
|
|
|
‡a
Author's IL-6 transsignaling: the in vivo consequences
|
|
670
|
|
|
‡a
Author's IL-6 transsignalling modulates the early effector phase of EAE and targets the blood-brain barrier
|
|
670
|
|
|
‡a
Author's IL-6 type cytokine receptor complexes: hexamer, tetramer or both?
|
|
670
|
|
|
‡a
Author's IL6/sIL6R complex contributes to emergency granulopoietic responses in G-CSF- and GM-CSF-deficient mice
|
|
670
|
|
|
‡a
Author's IL6 Trans-signaling Promotes KRAS-Driven Lung Carcinogenesis.
|
|
670
|
|
|
‡a
Author's Immunoadhesins of interleukin-6 and the IL-6/soluble IL-6R fusion protein hyper-IL-6
|
|
670
|
|
|
‡a
Author's Immunogene therapy of human melanoma. Phase I/II clinical trial.
|
|
670
|
|
|
‡a
Author's Impact of interleukin-6 classic- and trans-signaling on liver damage and regeneration
|
|
670
|
|
|
‡a
Author's Impaired hippocampus-dependent and -independent learning in IL-6 deficient mice
|
|
670
|
|
|
‡a
Author's In vitro reconstitution of recognition and activation complexes between interleukin-6 and gp130.
|
|
670
|
|
|
‡a
Author's In vivo evidence suggesting reciprocal renal hypoxia-inducible factor-1 upregulation and signal transducer and activator of transcription 3 activation in response to hypoxic and non-hypoxic stimuli
|
|
670
|
|
|
‡a
Author's Inactivation of IL-6 and soluble IL-6 receptor by neutrophil derived serine proteases in cystic fibrosis
|
|
670
|
|
|
‡a
Author's Increased inflammation and impaired resistance to Chlamydophila pneumoniae infection in Dusp1
|
|
670
|
|
|
‡a
Author's Increased inflammation and impaired resistance to Chlamydophila pneumoniae infection in Dusp1(-/-) mice: critical role of IL-6.
|
|
670
|
|
|
‡a
Author's Increased inflammation and lethality of Dusp1-/- mice in polymicrobial peritonitis models.
|
|
670
|
|
|
‡a
Author's Induction of strong hepatitis B virus
|
|
670
|
|
|
‡a
Author's Induction of strong hepatitis B virus (HBV) specific T helper cell and cytotoxic T lymphocyte responses by therapeutic vaccination in the trimera mouse model of chronic HBV infection.
|
|
670
|
|
|
‡a
Author's Inflammation-Induced IL-6 Functions as a Natural Brake on Macrophages and Limits GN.
|
|
670
|
|
|
‡a
Author's Inhibition of classic signaling is a novel function of soluble glycoprotein 130 (sgp130), which is controlled by the ratio of interleukin 6 and soluble interleukin 6 receptor
|
|
670
|
|
|
‡a
Author's Inhibition of IL-6 signaling significantly reduces primary tumor growth and recurrencies in orthotopic xenograft models of pancreatic cancer
|
|
670
|
|
|
‡a
Author's Inhibition of protein kinase II
|
|
670
|
|
|
‡a
Author's Inhibition of protein kinase II (CK2) prevents induced signal transducer and activator of transcription (STAT) 1/3 and constitutive STAT3 activation.
|
|
670
|
|
|
‡a
Author's Inhibition of T cell apoptosis in the aqueous humor of patients with uveitis by IL-6/soluble IL-6 receptor trans-signaling.
|
|
670
|
|
|
‡a
Author's Instructive Role of the Microenvironment in Preventing Renal Fibrosis
|
|
670
|
|
|
‡a
Author's Interaction of vascular smooth muscle cells and monocytes by soluble factors synergistically enhances IL-6 and MCP-1 production
|
|
670
|
|
|
‡a
Author's Interferon-gamma regulates alpha 2-macroglobulin and alpha 1-antichymotrypsin expression on the pretranslational level in HepG2 cells
|
|
670
|
|
|
‡a
Author's Interleukin-11-driven gastric tumourigenesis is independent of trans-signalling.
|
|
670
|
|
|
‡a
Author's Interleukin 17 drives vascular inflammation, endothelial dysfunction, and arterial hypertension in psoriasis-like skin disease
|
|
670
|
|
|
‡a
Author's Interleukin 27 induces differentiation of neural C6-precursor cells into astrocytes.
|
|
670
|
|
|
‡a
Author's Interleukin-31 and oncostatin-M mediate distinct signaling reactions and response patterns in lung epithelial cells
|
|
670
|
|
|
‡a
Author's Interleukin-6: a villain in the drama of pancreatic cancer development and progression
|
|
670
|
|
|
‡a
Author's Interleukin-6 and its receptor: from bench to bedside
|
|
670
|
|
|
‡a
Author's Interleukin-6 and its receptors: a highly regulated and dynamic system
|
|
670
|
|
|
‡a
Author's Interleukin-6 and neural stem cells: more than gliogenesis
|
|
670
|
|
|
‡a
Author's Interleukin-6 and soluble interleukin-6 receptor: direct stimulation of gp130 and hematopoiesis
|
|
670
|
|
|
‡a
Author's Interleukin-6 biology is coordinated by membrane bound and soluble receptors.
|
|
670
|
|
|
‡a
Author's Interleukin-6 biology is coordinated by membrane-bound and soluble receptors: role in inflammation and cancer
|
|
670
|
|
|
‡a
Author's Interleukin-6: Biology, signaling and strategies of blockade
|
|
670
|
|
|
‡a
Author's Interleukin 6-dependent genomic instability heralds accelerated carcinogenesis following liver regeneration on a background of chronic hepatitis
|
|
670
|
|
|
‡a
Author's Interleukin-6 Family Cytokines
|
|
670
|
|
|
‡a
Author's Interleukin-6: from basic biology to selective blockade of pro-inflammatory activities
|
|
670
|
|
|
‡a
Author's Interleukin-6 (IL-6) and its soluble receptor support survival of sensory neurons
|
|
670
|
|
|
‡a
Author's Interleukin-6 (IL-6) and soluble forms of IL-6 receptors are not altered in cerebrospinal fluid of Alzheimer's disease patients.
|
|
670
|
|
|
‡a
Author's Interleukin-6 in sepsis and capillary leakage syndrome
|
|
670
|
|
|
‡a
Author's Interleukin-6 receptor alpha blockade improves skin lesions in a murine model of systemic lupus erythematosus.
|
|
670
|
|
|
‡a
Author's Interleukin-6 receptor-interleukin-6 fusion proteins with enhanced interleukin-6 type pleiotropic activities
|
|
670
|
|
|
‡a
Author's Interleukin-6 receptor specific RNA aptamers for cargo delivery into target cells
|
|
670
|
|
|
‡a
Author's Interleukin-6 trans-signaling and colonic cancer associated with inflammatory bowel disease
|
|
670
|
|
|
‡a
Author's Interleukin-6 trans-signaling exacerbates inflammation and renal pathology in lupus-prone mice
|
|
670
|
|
|
‡a
Author's Interleukin-6 trans-signaling in inflammatory bowel disease
|
|
670
|
|
|
‡a
Author's Interleukin-6 trans-signaling increases the expression of carcinoembryonic antigen-related cell adhesion molecules 5 and 6 in colorectal cancer cells
|
|
670
|
|
|
‡a
Author's Interleukin-6 trans-signaling is a candidate mechanism to drive progression of human DCCs during clinical latency
|
|
670
|
|
|
‡a
Author's Interleukin 6 trans-signaling regulates basal synaptic transmission and sensitivity to pentylenetetrazole-induced seizures in mice
|
|
670
|
|
|
‡a
Author's Interleukin-6 Trans-Signaling Regulates Glycogen Consumption After d-Galactosamine-Induced Liver Damage
|
|
670
|
|
|
‡a
Author's Interleukin-6 trans signalling enhances photodynamic therapy by modulating cell cycling
|
|
670
|
|
|
‡a
Author's Interleukin 6/Wnt interactions in rheumatoid arthritis: interleukin 6 inhibits Wnt signaling in synovial fibroblasts and osteoblasts.
|
|
670
|
|
|
‡a
Author's Interplay between IFN-gamma and IL-6 signaling governs neutrophil trafficking and apoptosis during acute inflammation
|
|
670
|
|
|
‡a
Author's Intracellular retention of interleukin-6 abrogates signaling.
|
|
670
|
|
|
‡a
Author's Intravitreal injection of anti-Interleukin
|
|
670
|
|
|
‡a
Author's Intravitreal injection of anti-Interleukin (IL)-6 antibody attenuates experimental autoimmune uveitis in mice
|
|
670
|
|
|
‡a
Author's Introduction to stem cell biology in vitro. Threshold to the future.
|
|
670
|
|
|
‡a
Author's Is Interleukin-6 Receptor Blockade the Holy Grail for Inflammatory Diseases?
|
|
670
|
|
|
‡a
Author's Joint Reconstituted Signaling of the IL-6 Receptor via Extracellular Vesicles
|
|
670
|
|
|
‡a
Author's KSHV-encoded vIL-6 collaborates with deregulated c-Myc to drive plasmablastic neoplasms in mice.
|
|
670
|
|
|
‡a
Author's L1 is sequentially processed by two differently activated metalloproteases and presenilin/gamma-secretase and regulates neural cell adhesion, cell migration, and neurite outgrowth
|
|
670
|
|
|
‡a
Author's Laboratory diagnostics of murine blood for detection of mouse cytomegalovirus
|
|
670
|
|
|
‡a
Author's Laboratory diagnostics of murine blood for detection of mouse cytomegalovirus (MCMV)-induced hepatitis
|
|
670
|
|
|
‡a
Author's Leucine-58 in the putative 5th helical region of human interleukin (IL)-6 is important for activation of the IL-6 signal transducer, gp130
|
|
670
|
|
|
‡a
Author's Ligand/Receptor Signaling Threshold
|
|
670
|
|
|
‡a
Author's Ligand/Receptor Signaling Threshold (LIST) Model Accounts for gp130-Mediated Embryonic Stem Cell Self-Renewal Responses to LIF and HIL-6
|
|
670
|
|
|
‡a
Author's Liver regeneration induced by a designer human IL-6/sIL-6R fusion protein reverses severe hepatocellular injury.
|
|
670
|
|
|
‡a
Author's Liver sinusoidal endothelial cell cross-priming is supported by CD4 T cell-derived IL-2.
|
|
670
|
|
|
‡a
Author's Local blockade of IL-6R signaling induces lung CD4+ T cell apoptosis in a murine model of asthma via regulatory T cells
|
|
670
|
|
|
‡a
Author's Long-term survival of high-risk melanoma patients immunized with a Hyper-IL-6-modified allogeneic whole-cell vaccine after complete resection
|
|
670
|
|
|
‡a
Author's Loss of CD4+ T cell IL-6R expression during inflammation underlines a role for IL-6 trans signaling in the local maintenance of Th17 cells
|
|
670
|
|
|
‡a
Author's Loss of P53 Function Activates JAK2-STAT3 Signaling to Promote Pancreatic Tumor Growth, Stroma Modification, and Gemcitabine Resistance in Mice and Is Associated With Patient Survival.
|
|
670
|
|
|
‡a
Author's Maintenance of pluripotency in human embryonic stem cells is STAT3 independent
|
|
670
|
|
|
‡a
Author's Mechanistic insights into a TIMP3-sensitive pathway constitutively engaged in the regulation of cerebral hemodynamics
|
|
670
|
|
|
‡a
Author's Membrane-bound and soluble interleukin-6 receptor: studies on structure, regulation of expression, and signal transduction.
|
|
670
|
|
|
‡a
Author's Meprin Metalloproteases Generate Biologically Active Soluble Interleukin-6 Receptor to Induce Trans-Signaling
|
|
670
|
|
|
‡a
Author's Metalloprotease-mediated tumor cell shedding of B7-H6, the ligand of the natural killer cell-activating receptor NKp30.
|
|
670
|
|
|
‡a
Author's Microheterogeneity of human interleukin 6 synthesized by transfected NIH/3T3 cells: comparison with human monocytes, fibroblasts and endothelial cells.
|
|
670
|
|
|
‡a
Author's Model Based Targeting of IL-6-Induced Inflammatory Responses in Cultured Primary Hepatocytes to Improve Application of the JAK Inhibitor Ruxolitinib.
|
|
670
|
|
|
‡a
Author's Modelling IRF8 Deficient Human Hematopoiesis and Dendritic Cell Development with Engineered iPS Cells
|
|
670
|
|
|
‡a
Author's Molecular cloning and expression of an intracellular serpin: an elastase inhibitor from horse leucocytes
|
|
670
|
|
|
‡a
Author's Molecular cloning of mouse protein kinase C (PKC) cDNA from Swiss 3T3 fibroblasts.
|
|
670
|
|
|
‡a
Author's More about genetically modified tumour vaccines.
|
|
670
|
|
|
‡a
Author's Mouse neutrophils express the decoy type 2 interleukin-1 receptor
|
|
670
|
|
|
‡a
Author's Mouse neutrophils express the decoy type 2 interleukin-1 receptor (IL-1R2) constitutively and in acute inflammatory conditions
|
|
670
|
|
|
‡a
Author's mTNF reverse signalling induced by TNFα antagonists involves a GDF-1 dependent pathway: implications for Crohn's disease.
|
|
670
|
|
|
‡a
Author's Mucus Detachment by Host Metalloprotease Meprin β Requires Shedding of Its Inactive Pro-form, which Is Abrogated by the Pathogenic Protease RgpB.
|
|
670
|
|
|
‡a
Author's Multilevel regulation of IL-6R by IL-6-sIL-6R fusion protein according to the primitiveness of peripheral blood-derived CD133+ cells
|
|
670
|
|
|
‡a
Author's Murine stromal cells producing hyper-interleukin-6 and Flt3 ligand support expansion of early human hematopoietic progenitor cells without need of exogenous growth factors
|
|
670
|
|
|
‡a
Author's Mycobacterium simiae infection in two unrelated patients with different forms of inherited IFN-γR2 deficiency
|
|
670
|
|
|
‡a
Author's Myeloid A disintegrin and metalloproteinase domain 10 deficiency modulates atherosclerotic plaque composition by shifting the balance from inflammation toward fibrosis.
|
|
670
|
|
|
‡a
Author's N-linked glycosylation is essential for the stability but not the signaling function of the interleukin-6 signal transducer glycoprotein 130.
|
|
670
|
|
|
‡a
Author's Natural soluble interleukin-15Ralpha is generated by cleavage that involves the tumor necrosis factor-alpha-converting enzyme
|
|
670
|
|
|
‡a
Author's Natural soluble interleukin-15Ralpha is generated by cleavage that involves the tumor necrosis factor-alpha-converting enzyme (TACE/ADAM17).
|
|
670
|
|
|
‡a
Author's New developments in IL-6 dependent biology and therapy: where do we stand and what are the options?
|
|
670
|
|
|
‡a
Author's New insights into the role and signalling processes of gp130.
|
|
670
|
|
|
‡a
Author's New perspectives on the design of cytokines and growth factors.
|
|
670
|
|
|
‡a
Author's No inhibition of IL-27 signaling by soluble gp130.
|
|
670
|
|
|
‡a
Author's Not interferon, but interleukin-6 controls early gene expression in hepatitis B virus infection
|
|
670
|
|
|
‡a
Author's NOTCH Activation via gp130/STAT3 Signaling Confers Resistance to Chemoradiotherapy
|
|
670
|
|
|
‡a
Author's Novel path to activation of vascular smooth muscle cells: up-regulation of gp130 creates an autocrine activation loop by IL-6 and its soluble receptor
|
|
670
|
|
|
‡a
Author's Novel path to IL-6 trans-signaling through thrombin-induced soluble IL-6 receptor release by platelets
|
|
670
|
|
|
‡a
Author's Novel pathogenic mechanism of microbial metalloproteinases: liberation of membrane-anchored molecules in biologically active form exemplified by studies with the human interleukin-6 receptor
|
|
670
|
|
|
‡a
Author's Novel Potent Proline-Based Metalloproteinase Inhibitors: Design, (Radio)Synthesis, and First in Vivo Evaluation as Radiotracers for Positron Emission Tomography
|
|
670
|
|
|
‡a
Author's Novel regulatory mechanisms for generation of the soluble leptin receptor: implications for leptin action
|
|
670
|
|
|
‡a
Author's Oncogenic deletion mutants of gp130 signal from intracellular compartments
|
|
670
|
|
|
‡a
Author's Oncostatin M, leukaemia-inhibitory factor and interleukin 6 trigger different effects on alpha1-proteinase inhibitor synthesis in human lung-derived epithelial cells
|
|
670
|
|
|
‡a
Author's Opposing roles of gp130-mediated STAT-3 and ERK-1/ 2 signaling in liver progenitor cell migration and proliferation
|
|
670
|
|
|
‡a
Author's Optimization of retroviral-mediated gene transfer to human NOD/SCID mouse repopulating cord blood cells through a systematic analysis of protocol variables.
|
|
670
|
|
|
‡a
Author's Over-expressing the soluble gp130-Fc does not ameliorate methionine and choline deficient diet-induced non alcoholic steatohepatitis in mice.
|
|
670
|
|
|
‡a
Author's Parathyroid hormone induces expression and proteolytic processing of Rankl in primary murine osteoblasts
|
|
670
|
|
|
‡a
Author's Participation of Two Ser-Ser-Phe-Tyr Repeats in Interleukin-6
|
|
670
|
|
|
‡a
Author's Participation of Two Ser-Ser-Phe-Tyr Repeats in Interleukin-6 (IL-6)-Binding Sites of the Human IL-6 Receptor
|
|
670
|
|
|
‡a
Author's Peripheral and central blockade of interleukin-6 trans-signaling differentially affects sleep architecture
|
|
670
|
|
|
‡a
Author's Peripheral nerve regeneration and NGF-dependent neurite outgrowth of adult sensory neurons converge on STAT3 phosphorylation downstream of neuropoietic cytokine receptor gp130.
|
|
670
|
|
|
‡a
Author's Pharmaceutical relevant cytokine receptors: lessons from the first drafts of the human proteome
|
|
670
|
|
|
‡a
Author's Plasticity and cross-talk of interleukin 6-type cytokines
|
|
670
|
|
|
‡a
Author's Polo-like kinase 2, a novel ADAM17 signaling component, regulates tumor necrosis factor α ectodomain shedding
|
|
670
|
|
|
‡a
Author's Polycomb Group Protein Bmi1 Promotes Hematopoietic Cell Development from Embryonic Stem Cells
|
|
670
|
|
|
‡a
Author's Pore-forming toxins trigger shedding of receptors for interleukin 6 and lipopolysaccharide.
|
|
670
|
|
|
‡a
Author's Progressive and controlled development of mouse dendritic cells from Flt3+CD11b+ progenitors in vitro
|
|
670
|
|
|
‡a
Author's Protein kinase C activity is rate limiting for shedding of the interleukin-6 receptor.
|
|
670
|
|
|
‡a
Author's Proteolytic Cleavage Governs Interleukin-11 Trans-signaling
|
|
670
|
|
|
‡a
Author's Proteolytic Origin of the Soluble Human IL-6R In Vivo and a Decisive Role of N-Glycosylation
|
|
670
|
|
|
‡a
Author's Proteolytic steps within signaling cascades make these signaling pathways irreversible
|
|
670
|
|
|
‡a
Author's Radiation-Induced Loss of Salivary Gland Function Is Driven by Cellular Senescence and Prevented by IL6 Modulation
|
|
670
|
|
|
‡a
Author's RAID3--An interleukin-6 receptor-binding aptamer with post-selective modification-resistant affinity
|
|
670
|
|
|
‡a
Author's Recognition sequences and structural elements contribute to shedding susceptibility of membrane proteins.
|
|
670
|
|
|
‡a
Author's Recombinant human single chain Fv antibodies recognizing human interleukin-6. Specific targeting of cytokine-secreting cells.
|
|
670
|
|
|
‡a
Author's Recombinant IL-6 treatment protects mice from organ specific autoimmune disease by IL-6 classical signalling-dependent IL-1ra induction
|
|
670
|
|
|
‡a
Author's Recombinant p35 from bacteria can form Interleukin (IL-)12, but Not IL-35
|
|
670
|
|
|
‡a
Author's Recombinant soluble human interleukin-6 receptor. Expression in Escherichia coli, renaturation and purification
|
|
670
|
|
|
‡a
Author's Reduced virus specific T helper cell induction by autologous dendritic cells in patients with chronic hepatitis B - restoration by exogenous interleukin-12.
|
|
670
|
|
|
‡a
Author's Regulation of endotoxin-induced IL-6 production in liver sinusoidal endothelial cells and Kupffer cells by IL-10
|
|
670
|
|
|
‡a
Author's Regulation of Fibrotic Processes in the Liver by ADAM Proteases
|
|
670
|
|
|
‡a
Author's Regulation of the type II oncostatin M receptor expression in lung-derived epithelial cells
|
|
670
|
|
|
‡a
Author's Residues 77-95 of the human interleuken-6 protein are responsible for receptor binding and residues 41-56 for signal transduction
|
|
670
|
|
|
‡a
Author's RIP3, a kinase promoting necroptotic cell death, mediates adverse remodelling after myocardial infarction
|
|
670
|
|
|
‡a
Author's Role of IL-6 and the soluble IL-6 receptor in inhibition of VCAM-1 gene expression.
|
|
670
|
|
|
‡a
Author's Role of IL-6 trans-signaling in CCl₄induced liver damage
|
|
670
|
|
|
‡a
Author's Role of interleukin-6 and soluble IL-6 receptor in region-specific induction of astrocytic differentiation and neurotrophin expression
|
|
670
|
|
|
‡a
Author's Selective blockade of interleukin-6 trans-signaling improves survival in a murine polymicrobial sepsis model*
|
|
670
|
|
|
‡a
Author's Semisynthesis of Biologically Active Glycoforms of the Human Cytokine Interleukin 6
|
|
670
|
|
|
‡a
Author's Senescence-associated release of transmembrane proteins involves proteolytic processing by ADAM17 and microvesicle shedding.
|
|
670
|
|
|
‡a
Author's Shedding of Endogenous Interleukin-6 Receptor (IL-6R) Is Governed by A Disintegrin and Metalloproteinase (ADAM) Proteases while a Full-length IL-6R Isoform Localizes to Circulating Microvesicles
|
|
670
|
|
|
‡a
Author's Shedding of interleukin-6 receptor and tumor necrosis factor alpha. Contribution of the stalk sequence to the cleavage pattern of transmembrane proteins
|
|
670
|
|
|
‡a
Author's Short-term TNFα shedding is independent of cytoplasmic phosphorylation or furin cleavage of ADAM17.
|
|
670
|
|
|
‡a
Author's Signaling of human ciliary neurotrophic factor (CNTF) revisited. The interleukin-6 receptor can serve as an alpha-receptor for CTNF
|
|
670
|
|
|
‡a
Author's Site-directed mutagenesis of human CNTF: Functional analysis of recombinant variants
|
|
670
|
|
|
‡a
Author's Sleep enhances IL-6 trans-signaling in humans
|
|
670
|
|
|
‡a
Author's Soluble gp130 is the natural inhibitor of soluble interleukin-6 receptor transsignaling responses
|
|
670
|
|
|
‡a
Author's Soluble human interleukin-6 receptor. Expression in insect cells, purification and characterization
|
|
670
|
|
|
‡a
Author's Soluble human interleukin-6-receptor modulates interleukin-6-dependent N-glycosylation of alpha 1-protease inhibitor secreted by HepG2 cells
|
|
670
|
|
|
‡a
Author's Soluble IL-6 Receptor Governs IL-6 Activity in Experimental Arthritis: Blockade of Arthritis Severity by Soluble Glycoprotein 130
|
|
670
|
|
|
‡a
Author's Soluble IL-6 receptor leads to a paracrine modulation of the IL-6-induced hepatic acute phase response in double transgenic mice.
|
|
670
|
|
|
‡a
Author's Soluble interleukin-6 receptor (sIL-6R) makes IL-6R negative T cell line respond to IL-6; it inhibits TNF production.
|
|
670
|
|
|
‡a
Author's Soluble T cell immunoglobulin and mucin domain
|
|
670
|
|
|
‡a
Author's Soluble T cell immunoglobulin and mucin domain (TIM)-1 and -4 generated by A Disintegrin And Metalloprotease (ADAM)-10 and -17 bind to phosphatidylserine
|
|
670
|
|
|
‡a
Author's Soluble tumor necrosis factor (TNF) receptor-1 induces apoptosis via reverse TNF signaling and autocrine transforming growth factor-beta1.
|
|
670
|
|
|
‡a
Author's Species specificity of ADAM10 and ADAM17 proteins in interleukin-6
|
|
670
|
|
|
‡a
Author's Species specificity of ADAM10 and ADAM17 proteins in interleukin-6 (IL-6) trans-signaling and novel role of ADAM10 in inducible IL-6 receptor shedding
|
|
670
|
|
|
‡a
Author's Stabilized Interleukin-6 receptor binding RNA aptamers
|
|
670
|
|
|
‡a
Author's STAT3 activation via interleukin 6 trans-signalling contributes to ileitis in SAMP1/Yit mice
|
|
670
|
|
|
‡a
Author's STAT3 regulated ARF expression suppresses prostate cancer metastasis
|
|
670
|
|
|
‡a
Author's Stat3/Socs3 Activation by IL-6 Transsignaling Promotes Progression of Pancreatic Intraepithelial Neoplasia and Development of Pancreatic Cancer
|
|
670
|
|
|
‡a
Author's Statins potently reduce the cytokine-mediated IL-6 release in SMC/MNC cocultures
|
|
670
|
|
|
‡a
Author's Strawberry notch homolog 2 is a novel inflammatory response factor predominantly but not exclusively expressed by astrocytes in the central nervous system
|
|
670
|
|
|
‡a
Author's Structural and Functional Analyses of the Shedding Protease ADAM17 in HoxB8-Immortalized Macrophages and Dendritic-like Cells
|
|
670
|
|
|
‡a
Author's Structural and functional studies on the human hepatic interleukin-6 receptor. Molecular cloning and overexpression in HepG2 cells
|
|
670
|
|
|
‡a
Author's Structural and functional studies on the human interleukin-6 receptor. Binding, cross-linking, internalization, and degradation of interleukin-6 by fibroblasts transfected with human interleukin-6-receptor cDNA.
|
|
670
|
|
|
‡a
Author's Structure-function analysis of human interleukin-6. Evidence for the involvement of the carboxy-terminus in function.
|
|
670
|
|
|
‡a
Author's Structure-function analysis of interleukin-6 utilizing human/murine chimeric molecules. Involvement of two separate domains in receptor binding
|
|
670
|
|
|
‡a
Author's Structure-guided optimization of the interleukin-6 trans-signaling antagonist sgp130.
|
|
670
|
|
|
‡a
Author's Structure of an extracellular gp130 cytokine receptor signaling complex
|
|
670
|
|
|
‡a
Author's Studies on the structure and regulation of the human hepatic interleukin-6 receptor
|
|
670
|
|
|
‡a
Author's Suppressor of Cytokine Signaling 3 in Macrophages Prevents Exacerbated Interleukin-6-Dependent Arginase-1 Activity and Early Permissiveness to Experimental Tuberculosis.
|
|
670
|
|
|
‡a
Author's Sympathetic neurons can produce and respond to interleukin 6
|
|
670
|
|
|
‡a
Author's Synthesis of tissue inhibitor of metalloproteinase-1 (TIMP-1) in human hepatoma cells (HepG2). Up-regulation by interleukin-6 and transforming growth factor beta 1
|
|
670
|
|
|
‡a
Author's Synthetic Mimetics of the gp130 Binding Site for Viral Interleukin-6 as Inhibitors of the vIL-6-gp130 Interaction
|
|
670
|
|
|
‡a
Author's T-cell immunoglobulin and mucin domain 2
|
|
670
|
|
|
‡a
Author's T-cell immunoglobulin and mucin domain 2 (TIM-2) is a target of ADAM10-mediated ectodomain shedding
|
|
670
|
|
|
‡a
Author's TGF-beta suppresses tumor progression in colon cancer by inhibition of IL-6 trans-signaling.
|
|
670
|
|
|
‡a
Author's The ADAM17 Metalloproteinase Maintains Arterial Elasticity.
|
|
670
|
|
|
‡a
Author's The amino acid exchange R28E in ciliary neurotrophic factor (CNTF) abrogates interleukin-6 receptor-dependent but retains CNTF receptor-dependent signaling via glycoprotein 130 (gp130)/leukemia inhibitory factor receptor (LIFR).
|
|
670
|
|
|
‡a
Author's The balance between Treg and TH17 cells: CD11b and interleukin-6.
|
|
670
|
|
|
‡a
Author's The biology of interleukin-6 in the 21st century
|
|
670
|
|
|
‡a
Author's The designer cytokine hyper-interleukin-6 is a potent activator of STAT3-dependent gene transcription in vivo and in vitro.
|
|
670
|
|
|
‡a
Author's The disintegrin-like metalloproteinase ADAM10 is involved in constitutive cleavage of CX3CL1 (fractalkine) and regulates CX3CL1-mediated cell-cell adhesion
|
|
670
|
|
|
‡a
Author's The effect of gp130 stimulation on glutamate-induced excitotoxicity in primary hippocampal neurons
|
|
670
|
|
|
‡a
Author's The function of the soluble IL-6 receptor in vivo
|
|
670
|
|
|
‡a
Author's The gp130-stimulating designer cytokine hyper-IL-6 promotes the expansion of human hematopoietic progenitor cells capable to differentiate into functional dendritic cells
|
|
670
|
|
|
‡a
Author's The hepatic interleukin-6 receptor Down-regulation of the interleukin-6 binding subunit
|
|
670
|
|
|
‡a
Author's The hepatic interleukin-6 receptor Down-regulation of the interleukin-6 binding subunit (gp80) by its ligand
|
|
670
|
|
|
‡a
Author's The hepatic interleukin-6 receptor. Studies on its structure and regulation by phorbol 12-myristate 13-acetate-dexamethasone
|
|
670
|
|
|
‡a
Author's The hepatic microenvironment essentially determines tumor cell dormancy and metastatic outgrowth of pancreatic ductal adenocarcinoma.
|
|
670
|
|
|
‡a
Author's The human interleukin-6 (IL-6) receptor exists as a preformed dimer in the plasma membrane
|
|
670
|
|
|
‡a
Author's The IL-6-gp130-STAT3 pathway in hepatocytes triggers liver protection in T cell-mediated liver injury
|
|
670
|
|
|
‡a
Author's The IL-6/gp130/STAT3 signaling axis: recent advances towards specific inhibition
|
|
670
|
|
|
‡a
Author's The IL-6/sIL-6R complex as a novel target for therapeutic approaches
|
|
670
|
|
|
‡a
Author's The IL-6/sIL-6R fusion protein hyper-IL-6 promotes neurite outgrowth and neuron survival in cultured enteric neurons.
|
|
670
|
|
|
‡a
Author's The IL-6R alpha chain controls lung CD4+CD25+ Treg development and function during allergic airway inflammation in vivo.
|
|
670
|
|
|
‡a
Author's The IL-6R α chain controls lung CD4+CD25+ Treg development and function during allergic airway inflammation in vivo.
|
|
670
|
|
|
‡a
Author's The interleukin-6 cytokine system regulates epidermal permeability barrier homeostasis
|
|
670
|
|
|
‡a
Author's The interleukin 6 pathway and atherosclerosis
|
|
670
|
|
|
‡a
Author's The interleukin-6 receptor Asp358Ala single nucleotide polymorphism rs2228145 confers increased proteolytic conversion rates by ADAM proteases.
|
|
670
|
|
|
‡a
Author's The membrane-proximal domain of A Disintegrin and Metalloprotease 17
|
|
670
|
|
|
‡a
Author's The membrane-proximal domain of A Disintegrin and Metalloprotease 17 (ADAM17) is responsible for recognition of the interleukin-6 receptor and interleukin-1 receptor II
|
|
670
|
|
|
‡a
Author's The pro- and anti-inflammatory properties of the cytokine interleukin-6.
|
|
670
|
|
|
‡a
Author's The ratio of STAT1 to STAT3 expression is a determinant of colorectal cancer growth
|
|
670
|
|
|
‡a
Author's The regenerative activity of interleukin-6.
|
|
670
|
|
|
‡a
Author's The role of ADAM17 in the T-cell response against bacterial pathogens
|
|
670
|
|
|
‡a
Author's The role of IL-6 in host defence against infections: immunobiology and clinical implications
|
|
670
|
|
|
‡a
Author's The role of IL-6 trans-signaling in vascular leakage: implications for ovarian hyperstimulation syndrome in a murine model
|
|
670
|
|
|
‡a
Author's The role of interleukin-6 signaling in nervous tissue
|
|
670
|
|
|
‡a
Author's The role of metalloproteinase ADAM17 in regulating ICOS ligand-mediated humoral immune responses
|
|
670
|
|
|
‡a
Author's The role of soluble receptors in cytokine biology: the agonistic properties of the sIL-6R/IL-6 complex
|
|
670
|
|
|
‡a
Author's The shedding protease ADAM17: Physiology and pathophysiology
|
|
670
|
|
|
‡a
Author's The SLAM family member CD84 is regulated by ADAM10 and calpain in platelets
|
|
670
|
|
|
‡a
Author's The soluble human IL-6 receptor. Mutational characterization of the proteolytic cleavage site
|
|
670
|
|
|
‡a
Author's The soluble interleukin-6 receptor
|
|
670
|
|
|
‡a
Author's The Soluble Interleukin 6 Receptor: Advanced Therapeutic Options in Inflammation
|
|
670
|
|
|
‡a
Author's The soluble interleukin-6 receptor and related proteins
|
|
670
|
|
|
‡a
Author's The soluble Interleukin 6 receptor: generation and role in inflammation and cancer
|
|
670
|
|
|
‡a
Author's The solution structure of the membrane-proximal cytokine receptor domain of the human interleukin-6 receptor
|
|
670
|
|
|
‡a
Author's The stress-induced cytokine interleukin-6 decreases the inhibition/excitation ratio in the rat temporal cortex via trans-signaling
|
|
670
|
|
|
‡a
Author's The structure of the unliganded extracellular domain of the interleukin-6 signal transducer gp130 in solution
|
|
670
|
|
|
‡a
Author's The substrate degradome of meprin metalloproteases reveals an unexpected proteolytic link between meprin β and ADAM10.
|
|
670
|
|
|
‡a
Author's The transcription factor IFN regulatory factor-4 controls experimental colitis in mice via T cell-derived IL-6.
|
|
670
|
|
|
‡a
Author's The transcription factor NFATc2 controls IL-6-dependent T cell activation in experimental colitis
|
|
670
|
|
|
‡a
Author's The transcription factor repertoire of Flt3+ hematopoietic stem cells
|
|
670
|
|
|
‡a
Author's The transmembrane CXC-chemokine ligand 16 is induced by IFN-gamma and TNF-alpha and shed by the activity of the disintegrin-like metalloproteinase ADAM10
|
|
670
|
|
|
‡a
Author's The upper cytokine-binding module and the Ig-like domain of the leukaemia inhibitory factor (LIF) receptor are sufficient for a functional LIF receptor complex
|
|
670
|
|
|
‡a
Author's Therapeutic blockade of interleukin-6 in chronic inflammatory disease
|
|
670
|
|
|
‡a
Author's Therapeutic blockade of the interleukin-6 receptor
|
|
670
|
|
|
‡a
Author's Therapeutic blockade of the interleukin-6 receptor (IL-6R) allows sIL-6R generation by proteolytic cleavage
|
|
670
|
|
|
‡a
Author's Therapeutic strategies for the clinical blockade of IL-6/gp130 signaling
|
|
670
|
|
|
‡a
Author's Therapeutic targeting of IL-6 trans signaling counteracts STAT3 control of experimental inflammatory arthritis
|
|
670
|
|
|
‡a
Author's Therapeutic targeting of interleukin-6 trans-signaling does not affect the outcome of experimental tuberculosis
|
|
670
|
|
|
‡a
Author's Therapeutic Targeting of the IL-6 Trans-Signaling/Mechanistic Target of Rapamycin Complex 1 Axis in Pulmonary Emphysema.
|
|
670
|
|
|
‡a
Author's TIMP-1 protein expression is stimulated by IL-1 beta and IL-6 in primary rat hepatocytes
|
|
670
|
|
|
‡a
Author's TIMP-1 protein expression is stimulated by IL-1β and IL-6 in primary rat hepatocytes
|
|
670
|
|
|
‡a
Author's TIMP expression in toxic and cholestatic liver injury in rat
|
|
670
|
|
|
‡a
Author's Tissue inhibitor of metalloproteinases-2 (TIMP-2) in rat liver cells is increased by lipopolysaccharide and prostaglandin E2.
|
|
670
|
|
|
‡a
Author's TLR ligand-induced podosome disassembly in dendritic cells is ADAM17 dependent
|
|
670
|
|
|
‡a
Author's TNF-alpha-converting enzyme
|
|
670
|
|
|
‡a
Author's TNF-alpha-converting enzyme (TACE/ADAM17)-dependent loss of CD30 induced by proteasome inhibition through reactive oxygen species
|
|
670
|
|
|
‡a
Author's TNFα cleavage beyond TACE/ADAM17: matrix metalloproteinase 13 is a potential therapeutic target in sepsis and colitis
|
|
670
|
|
|
‡a
Author's Towards determining the differentiation program of antigen-presenting dendritic cells by transcriptional profiling
|
|
670
|
|
|
‡a
Author's Trans-presentation of IL-6 by dendritic cells is required for the priming of pathogenic TH17 cells
|
|
670
|
|
|
‡a
Author's Trans-Signaling Is a Dominant Mechanism for the Pathogenic Actions of Interleukin-6 in the Brain
|
|
670
|
|
|
‡a
Author's Transcription factor NFATc2 controls the emergence of colon cancer associated with IL-6-dependent colitis
|
|
670
|
|
|
‡a
Author's Transcriptional profiling identifies Id2 function in dendritic cell development
|
|
670
|
|
|
‡a
Author's Transgenic blockade of interleukin 6 transsignaling abrogates inflammation
|
|
670
|
|
|
‡a
Author's Transglutaminase-catalyzed covalent multimerization of Camelidae anti-human TNF single domain antibodies improves neutralizing activity.
|
|
670
|
|
|
‡a
Author's Transsignaling of Interleukin-6 Crucially Contributes to Atherosclerosis in Mice
|
|
670
|
|
|
‡a
Author's Trp53 deficiency protects against acute intestinal inflammation
|
|
670
|
|
|
‡a
Author's Tumor development in murine ulcerative colitis depends on MyD88 signaling of colonic F4/80+CD11b
|
|
670
|
|
|
‡a
Author's Tumor development in murine ulcerative colitis depends on MyD88 signaling of colonic F4/80+CD11b(high)Gr1(low) macrophages
|
|
670
|
|
|
‡a
Author's Unraveling viral interleukin-6 binding to gp130 and activation of STAT-signaling pathways independently of the interleukin-6 receptor
|
|
670
|
|
|
‡a
Author's Up- and down-regulation of granulocyte/macrophage-colony stimulating factor activity in murine skin increase susceptibility to skin carcinogenesis by independent mechanisms.
|
|
670
|
|
|
‡a
Author's Up-regulation of the interleukin-6-signal transducing protein (gp130) by interleukin-6 and dexamethasone in HepG2 cells
|
|
670
|
|
|
‡a
Author's Vagal nerve stimulation blocks interleukin 6-dependent synaptic hyperexcitability induced by lipopolysaccharide-induced acute stress in the rodent prefrontal cortex
|
|
670
|
|
|
‡a
Author's VEGF receptor signaling links inflammation and tumorigenesis in colitis-associated cancer
|
|
670
|
|
|
‡a
Author's Viral IL-6 Blocks Neutrophil Infiltration during Acute Inflammation
|
|
670
|
|
|
‡a
Author's Viral Interleukin-6: Structure, pathophysiology and strategies of neutralization
|
|
670
|
|
|
‡a
Author's Virokines in the pathogenesis of cancer: focus on human herpesvirus 8.
|
|
670
|
|
|
‡a
Author's Whole Cell Therapeutic Vaccine Modified With Hyper-IL6 for Combinational Treatment of Nonresected Advanced Melanoma
|
|
670
|
|
|
‡a
Author's Xenotropic and polytropic retrovirus receptor 1 regulates procoagulant platelet polyphosphate
|
|
670
|
|
|
‡a
Author's Yeast expression of the cytokine receptor domain of the soluble interleukin-6 receptor
|
|
670
|
|
|
‡a
Author's Zytokine: Biologie und therapeutische Relevanz
|
|
670
|
|
|
‡a
wikidata authority control
‡u
https://viaf.org/processed/DNB|140944362
|
|
670
|
|
|
‡a
wikidata authority control
‡u
https://viaf.org/processed/ISNI|0000000077993873
|
|
670
|
|
|
‡a
wikidata authority control
‡u
https://viaf.org/viaf/120209694
|
|
670
|
|
|
‡a
wikidata site links
‡u
https://de.wikipedia.org/wiki/Stefan_Rose-John
|
|
909
|
|
|
‡a
(orcid) 0000000275193279
‡9
1
|
|
919
|
|
|
‡a
acutephaseresponsefactorincreasedbindingandtargetgenetranscriptionduringliverregeneration
‡A
Acute-phase response factor, increased binding, and target gene transcription during liver regeneration.
‡9
1
|
|
919
|
|
|
‡a
activationoftheantiinflammatoryreflexblockslipopolysaccharideinduceddecreaseinsynapticinhibitioninthetemporalcortexoftherat
‡A
Activation of the anti-inflammatory reflex blocks lipopolysaccharide-induced decrease in synaptic inhibition in the temporal cortex of the rat.
‡9
1
|
|
919
|
|
|
‡a
activationofliver10receptorsinhibitsexperimentalfibrosisbyinterferingwithinterleukin6releasefrommacrophages
‡A
Activation of liver X receptors inhibits experimental fibrosis by interfering with interleukin-6 release from macrophages
‡9
1
|
|
919
|
|
|
‡a
activationofinterleukin6inducedglycoprotein130signaltransducerandactivatoroftranscription3pathwayinmesenchymalstemcellsenhanceshepaticdifferentiationproliferationandliverregeneration
‡A
Activation of interleukin-6-induced glycoprotein 130/signal transducer and activator of transcription 3 pathway in mesenchymal stem cells enhances hepatic differentiation, proliferation, and liver regeneration
‡9
1
|
|
919
|
|
|
‡a
activationofgp130byil6solubleil6receptorinducesneuronaldifferentiation
‡A
Activation of gp 130 by IL-6/soluble IL-6 receptor induces neuronal differentiation
‡9
1
|
|
919
|
|
|
‡a
activatedstatproteinsaparadoxicalconsequenceofinhibitedjakstatsignalingincytomegalovirusinfectedcells
‡A
"Activated" STAT proteins: a paradoxical consequence of inhibited JAK-STAT signaling in cytomegalovirus-infected cells
‡9
1
|
|
919
|
|
|
‡a
accuratevariantdetectionacrossnonamplifiedandwholegenomeamplifieddnausingtargetednextgenerationsequencing
‡A
Accurate variant detection across non-amplified and whole genome amplified DNA using targeted next generation sequencing
‡9
1
|
|
919
|
|
|
‡a
abrogationofviralinterleukin6vil6inducedsignalingbyintracellularretentionandneutralizationofvil6withanantivil6singlechainantibodyselectedbyphagedisplay
‡A
Abrogation of viral interleukin-6 (vIL-6)-induced signaling by intracellular retention and neutralization of vIL-6 with an anti-vIL-6 single-chain antibody selected by phage display
‡9
1
|
|
919
|
|
|
‡a
abrogationofviralinterleukin6
‡A
Abrogation of viral interleukin-6
‡9
1
|
|
919
|
|
|
‡a
variantinil6stwithaselectiveil11signalingdefectinhumanandmouse
‡A
A variant in IL6ST with a selective IL-11 signaling defect in human and mouse
‡9
1
|
|
919
|
|
|
‡a
switchfromwhitetobrownfatincreasesenergyexpenditureincancerassociatedcachexia
‡A
A switch from white to brown fat increases energy expenditure in cancer-associated cachexia
‡9
1
|
|
919
|
|
|
‡a
solubleformoftheinterleukin6familysignaltransducergp130isdimerizedviaa100terminaldisulfidebridgeresultingfromalternativemrnasplicing
‡A
A soluble form of the interleukin-6 family signal transducer gp130 is dimerized via a C-terminal disulfide bridge resulting from alternative mRNA splicing.
‡9
1
|
|
919
|
|
|
‡a
rolefortheimmunoglobulinlikedomainofthehumanil6receptorintracellularproteintransportandshedding
‡A
A role for the immunoglobulin-like domain of the human IL-6 receptor. Intracellular protein transport and shedding
‡9
1
|
|
919
|
|
|
‡a
roleforil27p28asanantagonistofgp130mediatedsignaling
‡A
A role for IL-27p28 as an antagonist of gp130-mediated signaling
‡9
1
|
|
919
|
|
|
‡a
novelsmallmoleculeinhibitortargetingtheil6receptorβsubunitglycoprotein130
‡A
A Novel Small-Molecule Inhibitor Targeting the IL-6 Receptor β Subunit, Glycoprotein 130.
‡9
1
|
|
919
|
|
|
‡a
novelbispecificsinglechainantibodyforadam17andcd3inducestcellmediatedlysisofprostatecancercells
‡A
A novel bispecific single-chain antibody for ADAM17 and CD3 induces T-cell-mediated lysis of prostate cancer cells
‡9
1
|
|
919
|
|
|
‡a
nonconservativepolymorphismintheil6signaltransduceril6stgp130isassociatedwithmyocardialinfarctioninahypertensivepopulation
‡A
A non-conservative polymorphism in the IL-6 signal transducer (IL6ST)/gp130 is associated with myocardial infarction in a hypertensive population
‡9
1
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|
919
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|
‡a
nonconservativepolymorphismintheil6signaltransducer
‡A
A non-conservative polymorphism in the IL-6 signal transducer
‡9
1
|
|
919
|
|
|
‡a
newtypeofcytokinereceptorantagonistdirectlytargetinggp130
‡A
A New Type of Cytokine Receptor Antagonist Directly Targeting gp130
‡9
1
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|
919
|
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|
‡a
newmultipletraumamodelofthemouse
‡A
A new multiple trauma model of the mouse
‡9
1
|
|
919
|
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|
‡a
keyroleforgp130expressedonperipheralsensorynervesinpathologicalpain
‡A
A key role for gp130 expressed on peripheral sensory nerves in pathological pain.
‡9
1
|
|
919
|
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|
‡a
metalloproteaseinhibitorblockssheddingoftheil6receptorandthep60tnfreceptor
‡A
A metalloprotease inhibitor blocks shedding of the IL-6 receptor and the p60 TNF receptor
‡9
1
|
|
919
|
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|
‡a
newhepatocytestimulatingfactorcardiotrophin1
‡A
A new hepatocyte stimulating factor: cardiotrophin-1
‡9
1
|
|
919
|
|
|
‡a
newhepatocytestimulatingfactorcardiotrophin1ct1
‡A
A new hepatocyte stimulating factor: cardiotrophin-1 (CT-1)
‡9
1
|
|
919
|
|
|
‡a
zytokinebiologieundtherapeutischerelevanz
‡A
Zytokine: Biologie und therapeutische Relevanz
‡9
1
|
|
919
|
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|
‡a
yeastexpressionofthecytokinereceptordomainofthesolubleinterleukin6receptor
‡A
Yeast expression of the cytokine receptor domain of the soluble interleukin-6 receptor
‡9
1
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|
919
|
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|
‡a
xenotropicandpolytropicretrovirusreceptor1regulatesprocoagulantplateletpolyphosphate
‡A
Xenotropic and polytropic retrovirus receptor 1 regulates procoagulant platelet polyphosphate
‡9
1
|
|
919
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|
‡a
wholecelltherapeuticvaccinemodifiedwithhyperil6forcombinationaltreatmentofnonresectedadvancedmelanoma
‡A
Whole Cell Therapeutic Vaccine Modified With Hyper-IL6 for Combinational Treatment of Nonresected Advanced Melanoma
‡9
1
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|
919
|
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‡a
virokinesinthepathogenesisofcancerfocusonhumanherpesvirus8
‡A
Virokines in the pathogenesis of cancer: focus on human herpesvirus 8.
‡9
1
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|
919
|
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‡a
viralinterleukin6structurepathophysiologyandstrategiesofneutralization
‡A
Viral Interleukin-6: Structure, pathophysiology and strategies of neutralization
‡9
1
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|
919
|
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|
‡a
viralil6blocksneutrophilinfiltrationduringacuteinflammation
‡A
Viral IL-6 Blocks Neutrophil Infiltration during Acute Inflammation
‡9
1
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|
919
|
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|
‡a
vegfreceptorsignalinglinksinflammationandtumorigenesisincolitisassociatedcancer
‡A
VEGF receptor signaling links inflammation and tumorigenesis in colitis-associated cancer
‡9
1
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|
919
|
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|
‡a
vagalnervestimulationblocksinterleukin6dependentsynaptichyperexcitabilityinducedbylipopolysaccharideinducedacutestressintherodentprefrontalcortex
‡A
Vagal nerve stimulation blocks interleukin 6-dependent synaptic hyperexcitability induced by lipopolysaccharide-induced acute stress in the rodent prefrontal cortex
‡9
1
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|
919
|
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|
‡a
upregulationoftheinterleukin6signaltransducingproteingp130byinterleukin6anddexamethasoneinhepg2cells
‡A
Up-regulation of the interleukin-6-signal transducing protein (gp130) by interleukin-6 and dexamethasone in HepG2 cells
‡9
1
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|
919
|
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|
‡a
upanddownregulationofgranulocytemacrophagecolonystimulatingfactoractivityinmurineskinincreasesusceptibilitytoskincarcinogenesisbyindependentmechanisms
‡A
Up- and down-regulation of granulocyte/macrophage-colony stimulating factor activity in murine skin increase susceptibility to skin carcinogenesis by independent mechanisms.
‡9
1
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|
919
|
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|
‡a
unravelingviralinterleukin6bindingtogp130andactivationofstatsignalingpathwaysindependentlyoftheinterleukin6receptor
‡A
Unraveling viral interleukin-6 binding to gp130 and activation of STAT-signaling pathways independently of the interleukin-6 receptor
‡9
1
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|
919
|
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|
‡a
tumordevelopmentinmurineulcerativecolitisdependsonmyd88signalingofcolonicf480+cd11bhighgr1lowmacrophages
‡A
Tumor development in murine ulcerative colitis depends on MyD88 signaling of colonic F4/80+CD11b(high)Gr1(low) macrophages
‡9
1
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|
919
|
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|
‡a
tumordevelopmentinmurineulcerativecolitisdependsonmyd88signalingofcolonicf480+cd11b
‡A
Tumor development in murine ulcerative colitis depends on MyD88 signaling of colonic F4/80+CD11b
‡9
1
|
|
919
|
|
|
‡a
trp53deficiencyprotectsagainstacuteintestinalinflammation
‡A
Trp53 deficiency protects against acute intestinal inflammation
‡9
1
|
|
919
|
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|
‡a
transsignalingofinterleukin6cruciallycontributestoatherosclerosisinmice
‡A
Transsignaling of Interleukin-6 Crucially Contributes to Atherosclerosis in Mice
‡9
1
|
|
919
|
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|
‡a
transglutaminasecatalyzedcovalentmultimerizationofcamelidaeantihumantnfsingledomainantibodiesimprovesneutralizingactivity
‡A
Transglutaminase-catalyzed covalent multimerization of Camelidae anti-human TNF single domain antibodies improves neutralizing activity.
‡9
1
|
|
919
|
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|
‡a
transgenicblockadeofinterleukin6transsignalingabrogatesinflammation
‡A
Transgenic blockade of interleukin 6 transsignaling abrogates inflammation
‡9
1
|
|
919
|
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|
‡a
transcriptionalprofilingidentifiesid2functionindendriticcelldevelopment
‡A
Transcriptional profiling identifies Id2 function in dendritic cell development
‡9
1
|
|
919
|
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|
‡a
transcriptionfactornfatc2controlstheemergenceofcoloncancerassociatedwithil6dependentcolitis
‡A
Transcription factor NFATc2 controls the emergence of colon cancer associated with IL-6-dependent colitis
‡9
1
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|
919
|
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|
‡a
transsignalingisadominantmechanismforthepathogenicactionsofinterleukin6inthebrain
‡A
Trans-Signaling Is a Dominant Mechanism for the Pathogenic Actions of Interleukin-6 in the Brain
‡9
1
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|
919
|
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|
‡a
transpresentationofil6bydendriticcellsisrequiredfortheprimingofpathogenicth17cells
‡A
Trans-presentation of IL-6 by dendritic cells is required for the priming of pathogenic TH17 cells
‡9
1
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|
919
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|
‡a
towardsdeterminingthedifferentiationprogramofantigenpresentingdendriticcellsbytranscriptionalprofiling
‡A
Towards determining the differentiation program of antigen-presenting dendritic cells by transcriptional profiling
‡9
1
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|
919
|
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|
‡a
tnfαcleavagebeyondtaceadam17matrixmetalloproteinase13isapotentialtherapeutictargetinsepsisandcolitis
‡A
TNFα cleavage beyond TACE/ADAM17: matrix metalloproteinase 13 is a potential therapeutic target in sepsis and colitis
‡9
1
|
|
919
|
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|
‡a
tnfalphaconvertingenzymetaceadam17dependentlossofcd30inducedbyproteasomeinhibitionthroughreactiveoxygenspecies
‡A
TNF-alpha-converting enzyme (TACE/ADAM17)-dependent loss of CD30 induced by proteasome inhibition through reactive oxygen species
‡9
1
|
|
919
|
|
|
‡a
tnfalphaconvertingenzyme
‡A
TNF-alpha-converting enzyme
‡9
1
|
|
919
|
|
|
‡a
tlrligandinducedpodosomedisassemblyindendriticcellsisadam17dependent
‡A
TLR ligand-induced podosome disassembly in dendritic cells is ADAM17 dependent
‡9
1
|
|
919
|
|
|
‡a
tissueinhibitorofmetalloproteinases2timp2inratlivercellsisincreasedbylipopolysaccharideandprostaglandine2
‡A
Tissue inhibitor of metalloproteinases-2 (TIMP-2) in rat liver cells is increased by lipopolysaccharide and prostaglandin E2.
‡9
1
|
|
919
|
|
|
‡a
timpexpressionintoxicandcholestaticliverinjuryinrat
‡A
TIMP expression in toxic and cholestatic liver injury in rat
‡9
1
|
|
919
|
|
|
‡a
timp1proteinexpressionisstimulatedbyil1βandil6inprimaryrathepatocytes
‡A
TIMP-1 protein expression is stimulated by IL-1β and IL-6 in primary rat hepatocytes
‡9
1
|
|
919
|
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|
‡a
timp1proteinexpressionisstimulatedbyil1betaandil6inprimaryrathepatocytes
‡A
TIMP-1 protein expression is stimulated by IL-1 beta and IL-6 in primary rat hepatocytes
‡9
1
|
|
919
|
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|
‡a
therapeutictargetingoftheil6transsignalingmechanistictargetofrapamycincomplex1axisinpulmonaryemphysema
‡A
Therapeutic Targeting of the IL-6 Trans-Signaling/Mechanistic Target of Rapamycin Complex 1 Axis in Pulmonary Emphysema.
‡9
1
|
|
919
|
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|
‡a
therapeutictargetingofinterleukin6transsignalingdoesnotaffecttheoutcomeofexperimentaltuberculosis
‡A
Therapeutic targeting of interleukin-6 trans-signaling does not affect the outcome of experimental tuberculosis
‡9
1
|
|
919
|
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|
‡a
therapeutictargetingofil6transsignalingcounteractsstat3controlofexperimentalinflammatoryarthritis
‡A
Therapeutic targeting of IL-6 trans signaling counteracts STAT3 control of experimental inflammatory arthritis
‡9
1
|
|
919
|
|
|
‡a
therapeuticstrategiesfortheclinicalblockadeofil6gp130signaling
‡A
Therapeutic strategies for the clinical blockade of IL-6/gp130 signaling
‡9
1
|
|
919
|
|
|
‡a
therapeuticblockadeoftheinterleukin6receptoril6rallowssil6rgenerationbyproteolyticcleavage
‡A
Therapeutic blockade of the interleukin-6 receptor (IL-6R) allows sIL-6R generation by proteolytic cleavage
‡9
1
|
|
919
|
|
|
‡a
therapeuticblockadeoftheinterleukin6receptor
‡A
Therapeutic blockade of the interleukin-6 receptor
‡9
1
|
|
919
|
|
|
‡a
therapeuticblockadeofinterleukin6inchronicinflammatorydisease
‡A
Therapeutic blockade of interleukin-6 in chronic inflammatory disease
‡9
1
|
|
919
|
|
|
‡a
uppercytokinebindingmoduleandtheiglikedomainoftheleukaemiainhibitoryfactorlifreceptoraresufficientforafunctionallifreceptorcomplex
‡A
The upper cytokine-binding module and the Ig-like domain of the leukaemia inhibitory factor (LIF) receptor are sufficient for a functional LIF receptor complex
‡9
1
|
|
919
|
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|
‡a
transmembrane190chemokineligand16isinducedbyifngammaandtnfalphaandshedbytheactivityofthedisintegrinlikemetalloproteinaseadam10
‡A
The transmembrane CXC-chemokine ligand 16 is induced by IFN-gamma and TNF-alpha and shed by the activity of the disintegrin-like metalloproteinase ADAM10
‡9
1
|
|
919
|
|
|
‡a
transcriptionfactorrepertoireofflt3+hematopoieticstemcells
‡A
The transcription factor repertoire of Flt3+ hematopoietic stem cells
‡9
1
|
|
919
|
|
|
‡a
transcriptionfactornfatc2controlsil6dependenttcellactivationinexperimentalcolitis
‡A
The transcription factor NFATc2 controls IL-6-dependent T cell activation in experimental colitis
‡9
1
|
|
919
|
|
|
‡a
transcriptionfactorifnregulatoryfactor4controlsexperimentalcolitisinmiceviatcellderivedil6
‡A
The transcription factor IFN regulatory factor-4 controls experimental colitis in mice via T cell-derived IL-6.
‡9
1
|
|
919
|
|
|
‡a
substratedegradomeofmeprinmetalloproteasesrevealsanunexpectedproteolyticlinkbetweenmeprinβandadam10
‡A
The substrate degradome of meprin metalloproteases reveals an unexpected proteolytic link between meprin β and ADAM10.
‡9
1
|
|
919
|
|
|
‡a
structureoftheunligandedextracellulardomainoftheinterleukin6signaltransducergp130insolution
‡A
The structure of the unliganded extracellular domain of the interleukin-6 signal transducer gp130 in solution
‡9
1
|
|
919
|
|
|
‡a
stressinducedcytokineinterleukin6decreasestheinhibitionexcitationratiointherattemporalcortexviatranssignaling
‡A
The stress-induced cytokine interleukin-6 decreases the inhibition/excitation ratio in the rat temporal cortex via trans-signaling
‡9
1
|
|
919
|
|
|
‡a
solutionstructureofthemembraneproximalcytokinereceptordomainofthehumaninterleukin6receptor
‡A
The solution structure of the membrane-proximal cytokine receptor domain of the human interleukin-6 receptor
‡9
1
|
|
919
|
|
|
‡a
solubleinterleukin6receptorgenerationandroleininflammationandcancer
‡A
The soluble Interleukin 6 receptor: generation and role in inflammation and cancer
‡9
1
|
|
919
|
|
|
‡a
solubleinterleukin6receptorandrelatedproteins
‡A
The soluble interleukin-6 receptor and related proteins
‡9
1
|
|
919
|
|
|
‡a
solubleinterleukin6receptoradvancedtherapeuticoptionsininflammation
‡A
The Soluble Interleukin 6 Receptor: Advanced Therapeutic Options in Inflammation
‡9
1
|
|
919
|
|
|
‡a
solubleinterleukin6receptor
‡A
The soluble interleukin-6 receptor
‡9
1
|
|
919
|
|
|
‡a
solublehumanil6receptormutationalcharacterizationoftheproteolyticcleavagesite
‡A
The soluble human IL-6 receptor. Mutational characterization of the proteolytic cleavage site
‡9
1
|
|
919
|
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|
‡a
slamfamilymembercd84isregulatedbyadam10andcalpaininplatelets
‡A
The SLAM family member CD84 is regulated by ADAM10 and calpain in platelets
‡9
1
|
|
919
|
|
|
‡a
sheddingproteaseadam17physiologyandpathophysiology
‡A
The shedding protease ADAM17: Physiology and pathophysiology
‡9
1
|
|
919
|
|
|
‡a
roleofsolublereceptorsincytokinebiologytheagonisticpropertiesofthesil6ril6complex
‡A
The role of soluble receptors in cytokine biology: the agonistic properties of the sIL-6R/IL-6 complex
‡9
1
|
|
919
|
|
|
‡a
roleofmetalloproteinaseadam17inregulatingicosligandmediatedhumoralimmuneresponses
‡A
The role of metalloproteinase ADAM17 in regulating ICOS ligand-mediated humoral immune responses
‡9
1
|
|
919
|
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|
‡a
roleofinterleukin6signalinginnervoustissue
‡A
The role of interleukin-6 signaling in nervous tissue
‡9
1
|
|
919
|
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|
‡a
roleofil6transsignalinginvascularleakageimplicationsforovarianhyperstimulationsyndromeinamurinemodel
‡A
The role of IL-6 trans-signaling in vascular leakage: implications for ovarian hyperstimulation syndrome in a murine model
‡9
1
|
|
919
|
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|
‡a
roleofil6inhostdefenceagainstinfectionsimmunobiologyandclinicalimplications
‡A
The role of IL-6 in host defence against infections: immunobiology and clinical implications
‡9
1
|
|
919
|
|
|
‡a
roleofadam17inthetcellresponseagainstbacterialpathogens
‡A
The role of ADAM17 in the T-cell response against bacterial pathogens
‡9
1
|
|
919
|
|
|
‡a
regenerativeactivityofinterleukin6
‡A
The regenerative activity of interleukin-6.
‡9
1
|
|
919
|
|
|
‡a
ratioofstat1tostat3expressionisadeterminantofcolorectalcancergrowth
‡A
The ratio of STAT1 to STAT3 expression is a determinant of colorectal cancer growth
‡9
1
|
|
919
|
|
|
‡a
proandantiinflammatorypropertiesofthecytokineinterleukin6
‡A
The pro- and anti-inflammatory properties of the cytokine interleukin-6.
‡9
1
|
|
919
|
|
|
‡a
membraneproximaldomainofadisintegrinandmetalloprotease17adam17isresponsibleforrecognitionoftheinterleukin6receptorandinterleukin1receptor2
‡A
The membrane-proximal domain of A Disintegrin and Metalloprotease 17 (ADAM17) is responsible for recognition of the interleukin-6 receptor and interleukin-1 receptor II
‡9
1
|
|
919
|
|
|
‡a
membraneproximaldomainofadisintegrinandmetalloprotease17
‡A
The membrane-proximal domain of A Disintegrin and Metalloprotease 17
‡9
1
|
|
919
|
|
|
‡a
interleukin6receptorasp358alasinglenucleotidepolymorphismrs2228145confersincreasedproteolyticconversionratesbyadamproteases
‡A
The interleukin-6 receptor Asp358Ala single nucleotide polymorphism rs2228145 confers increased proteolytic conversion rates by ADAM proteases.
‡9
1
|
|
919
|
|
|
‡a
interleukin6pathwayandatherosclerosis
‡A
The interleukin 6 pathway and atherosclerosis
‡9
1
|
|
919
|
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|
‡a
interleukin6cytokinesystemregulatesepidermalpermeabilitybarrierhomeostasis
‡A
The interleukin-6 cytokine system regulates epidermal permeability barrier homeostasis
‡9
1
|
|
919
|
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|
‡a
il6rαchaincontrolslungcd4+cd25+tregdevelopmentandfunctionduringallergicairwayinflammationinvivo
‡A
The IL-6R α chain controls lung CD4+CD25+ Treg development and function during allergic airway inflammation in vivo.
‡9
1
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|
919
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‡a
il6ralphachaincontrolslungcd4+cd25+tregdevelopmentandfunctionduringallergicairwayinflammationinvivo
‡A
The IL-6R alpha chain controls lung CD4+CD25+ Treg development and function during allergic airway inflammation in vivo.
‡9
1
|
|
919
|
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|
‡a
il6sil6rfusionproteinhyperil6promotesneuriteoutgrowthandneuronsurvivalinculturedentericneurons
‡A
The IL-6/sIL-6R fusion protein hyper-IL-6 promotes neurite outgrowth and neuron survival in cultured enteric neurons.
‡9
1
|
|
919
|
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|
‡a
il6sil6rcomplexasanoveltargetfortherapeuticapproaches
‡A
The IL-6/sIL-6R complex as a novel target for therapeutic approaches
‡9
1
|
|
919
|
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|
‡a
il6gp130stat3signalingaxisrecentadvancestowardsspecificinhibition
‡A
The IL-6/gp130/STAT3 signaling axis: recent advances towards specific inhibition
‡9
1
|
|
919
|
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|
‡a
il6gp130stat3pathwayinhepatocytestriggersliverprotectionintcellmediatedliverinjury
‡A
The IL-6-gp130-STAT3 pathway in hepatocytes triggers liver protection in T cell-mediated liver injury
‡9
1
|
|
919
|
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|
‡a
humaninterleukin6il6receptorexistsasapreformeddimerintheplasmamembrane
‡A
The human interleukin-6 (IL-6) receptor exists as a preformed dimer in the plasma membrane
‡9
1
|
|
919
|
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|
‡a
hepaticmicroenvironmentessentiallydeterminestumorcelldormancyandmetastaticoutgrowthofpancreaticductaladenocarcinoma
‡A
The hepatic microenvironment essentially determines tumor cell dormancy and metastatic outgrowth of pancreatic ductal adenocarcinoma.
‡9
1
|
|
919
|
|
|
‡a
hepaticinterleukin6receptorstudiesonitsstructureandregulationbyphorbol12myristate13acetatedexamethasone
‡A
The hepatic interleukin-6 receptor. Studies on its structure and regulation by phorbol 12-myristate 13-acetate-dexamethasone
‡9
1
|
|
919
|
|
|
‡a
hepaticinterleukin6receptordownregulationoftheinterleukin6bindingsubunitgp80byitsligand
‡A
The hepatic interleukin-6 receptor Down-regulation of the interleukin-6 binding subunit (gp80) by its ligand
‡9
1
|
|
919
|
|
|
‡a
hepaticinterleukin6receptordownregulationoftheinterleukin6bindingsubunit
‡A
The hepatic interleukin-6 receptor Down-regulation of the interleukin-6 binding subunit
‡9
1
|
|
919
|
|
|
‡a
gp130stimulatingdesignercytokinehyperil6promotestheexpansionofhumanhematopoieticprogenitorcellscapabletodifferentiateintofunctionaldendriticcells
‡A
The gp130-stimulating designer cytokine hyper-IL-6 promotes the expansion of human hematopoietic progenitor cells capable to differentiate into functional dendritic cells
‡9
1
|
|
919
|
|
|
‡a
functionofthesolubleil6receptorinvivo
‡A
The function of the soluble IL-6 receptor in vivo
‡9
1
|
|
919
|
|
|
‡a
effectofgp130stimulationonglutamateinducedexcitotoxicityinprimaryhippocampalneurons
‡A
The effect of gp130 stimulation on glutamate-induced excitotoxicity in primary hippocampal neurons
‡9
1
|
|
919
|
|
|
‡a
disintegrinlikemetalloproteinaseadam10isinvolvedinconstitutivecleavageofcx3cl1fractalkineandregulatescx3cl1mediatedcellcelladhesion
‡A
The disintegrin-like metalloproteinase ADAM10 is involved in constitutive cleavage of CX3CL1 (fractalkine) and regulates CX3CL1-mediated cell-cell adhesion
‡9
1
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|
919
|
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|
‡a
designercytokinehyperinterleukin6isapotentactivatorofstat3dependentgenetranscriptioninvivoandinvitro
‡A
The designer cytokine hyper-interleukin-6 is a potent activator of STAT3-dependent gene transcription in vivo and in vitro.
‡9
1
|
|
919
|
|
|
‡a
biologyofinterleukin6inthe21stcentury
‡A
The biology of interleukin-6 in the 21st century
‡9
1
|
|
919
|
|
|
‡a
balancebetweentregandth17cellscd11bandinterleukin6
‡A
The balance between Treg and TH17 cells: CD11b and interleukin-6.
‡9
1
|
|
919
|
|
|
‡a
aminoacidexchanger28einciliaryneurotrophicfactorcntfabrogatesinterleukin6receptordependentbutretainscntfreceptordependentsignalingviaglycoprotein130gp130leukemiainhibitoryfactorreceptorlifr
‡A
The amino acid exchange R28E in ciliary neurotrophic factor (CNTF) abrogates interleukin-6 receptor-dependent but retains CNTF receptor-dependent signaling via glycoprotein 130 (gp130)/leukemia inhibitory factor receptor (LIFR).
‡9
1
|
|
919
|
|
|
‡a
adam17metalloproteinasemaintainsarterialelasticity
‡A
The ADAM17 Metalloproteinase Maintains Arterial Elasticity.
‡9
1
|
|
919
|
|
|
‡a
tgfbetasuppressestumorprogressionincoloncancerbyinhibitionofil6transsignaling
‡A
TGF-beta suppresses tumor progression in colon cancer by inhibition of IL-6 trans-signaling.
‡9
1
|
|
919
|
|
|
‡a
tcellimmunoglobulinandmucindomain2tim2isatargetofadam10mediatedectodomainshedding
‡A
T-cell immunoglobulin and mucin domain 2 (TIM-2) is a target of ADAM10-mediated ectodomain shedding
‡9
1
|
|
919
|
|
|
‡a
tcellimmunoglobulinandmucindomain2
‡A
T-cell immunoglobulin and mucin domain 2
‡9
1
|
|
919
|
|
|
‡a
syntheticmimeticsofthegp130bindingsiteforviralinterleukin6asinhibitorsofthevil6gp130interaction
‡A
Synthetic Mimetics of the gp130 Binding Site for Viral Interleukin-6 as Inhibitors of the vIL-6-gp130 Interaction
‡9
1
|
|
919
|
|
|
‡a
synthesisoftissueinhibitorofmetalloproteinase1timp1inhumanhepatomacellshepg2upregulationbyinterleukin6andtransforminggrowthfactorbeta1
‡A
Synthesis of tissue inhibitor of metalloproteinase-1 (TIMP-1) in human hepatoma cells (HepG2). Up-regulation by interleukin-6 and transforming growth factor beta 1
‡9
1
|
|
919
|
|
|
‡a
sympatheticneuronscanproduceandrespondtointerleukin6
‡A
Sympathetic neurons can produce and respond to interleukin 6
‡9
1
|
|
919
|
|
|
‡a
suppressorofcytokinesignaling3inmacrophagespreventsexacerbatedinterleukin6dependentarginase1activityandearlypermissivenesstoexperimentaltuberculosis
‡A
Suppressor of Cytokine Signaling 3 in Macrophages Prevents Exacerbated Interleukin-6-Dependent Arginase-1 Activity and Early Permissiveness to Experimental Tuberculosis.
‡9
1
|
|
919
|
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|
‡a
studiesonthestructureandregulationofthehumanhepaticinterleukin6receptor
‡A
Studies on the structure and regulation of the human hepatic interleukin-6 receptor
‡9
1
|
|
919
|
|
|
‡a
structureofanextracellulargp130cytokinereceptorsignalingcomplex
‡A
Structure of an extracellular gp130 cytokine receptor signaling complex
‡9
1
|
|
919
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|
‡a
structureguidedoptimizationoftheinterleukin6transsignalingantagonistsgp130
‡A
Structure-guided optimization of the interleukin-6 trans-signaling antagonist sgp130.
‡9
1
|
|
919
|
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|
‡a
structurefunctionanalysisofinterleukin6utilizinghumanmurinechimericmoleculesinvolvementof2separatedomainsinreceptorbinding
‡A
Structure-function analysis of interleukin-6 utilizing human/murine chimeric molecules. Involvement of two separate domains in receptor binding
‡9
1
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|
919
|
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|
‡a
structurefunctionanalysisofhumaninterleukin6evidencefortheinvolvementofthecarboxyterminusinfunction
‡A
Structure-function analysis of human interleukin-6. Evidence for the involvement of the carboxy-terminus in function.
‡9
1
|
|
919
|
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|
‡a
structuralandfunctionalstudiesonthehumaninterleukin6receptorbindingcrosslinkinginternalizationanddegradationofinterleukin6byfibroblaststransfectedwithhumaninterleukin6receptorcdna
‡A
Structural and functional studies on the human interleukin-6 receptor. Binding, cross-linking, internalization, and degradation of interleukin-6 by fibroblasts transfected with human interleukin-6-receptor cDNA.
‡9
1
|
|
919
|
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|
‡a
structuralandfunctionalstudiesonthehumanhepaticinterleukin6receptormolecularcloningandoverexpressioninhepg2cells
‡A
Structural and functional studies on the human hepatic interleukin-6 receptor. Molecular cloning and overexpression in HepG2 cells
‡9
1
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|
919
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|
‡a
structuralandfunctionalanalysesofthesheddingproteaseadam17inhoxb8immortalizedmacrophagesanddendriticlikecells
‡A
Structural and Functional Analyses of the Shedding Protease ADAM17 in HoxB8-Immortalized Macrophages and Dendritic-like Cells
‡9
1
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|
919
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‡a
strawberrynotchhomolog2isanovelinflammatoryresponsefactorpredominantlybutnotexclusivelyexpressedbyastrocytesinthecentralnervoussystem
‡A
Strawberry notch homolog 2 is a novel inflammatory response factor predominantly but not exclusively expressed by astrocytes in the central nervous system
‡9
1
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|
919
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|
‡a
statinspotentlyreducethecytokinemediatedil6releaseinsmcmnccocultures
‡A
Statins potently reduce the cytokine-mediated IL-6 release in SMC/MNC cocultures
‡9
1
|
|
919
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|
‡a
stat3socs3activationbyil6transsignalingpromotesprogressionofpancreaticintraepithelialneoplasiaanddevelopmentofpancreaticcancer
‡A
Stat3/Socs3 Activation by IL-6 Transsignaling Promotes Progression of Pancreatic Intraepithelial Neoplasia and Development of Pancreatic Cancer
‡9
1
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|
919
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‡a
stat3regulatedarfexpressionsuppressesprostatecancermetastasis
‡A
STAT3 regulated ARF expression suppresses prostate cancer metastasis
‡9
1
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|
919
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|
‡a
stat3activationviainterleukin6transsignallingcontributestoileitisinsamp1yitmice
‡A
STAT3 activation via interleukin 6 trans-signalling contributes to ileitis in SAMP1/Yit mice
‡9
1
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919
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‡a
stabilizedinterleukin6receptorbindingrnaaptamers
‡A
Stabilized Interleukin-6 receptor binding RNA aptamers
‡9
1
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|
919
|
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|
‡a
speciesspecificityofadam10andadam17proteinsininterleukin6il6transsignalingandnovelroleofadam10ininducibleil6receptorshedding
‡A
Species specificity of ADAM10 and ADAM17 proteins in interleukin-6 (IL-6) trans-signaling and novel role of ADAM10 in inducible IL-6 receptor shedding
‡9
1
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|
919
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‡a
speciesspecificityofadam10andadam17proteinsininterleukin6
‡A
Species specificity of ADAM10 and ADAM17 proteins in interleukin-6
‡9
1
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|
919
|
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|
‡a
solubletumornecrosisfactortnfreceptor1inducesapoptosisviareversetnfsignalingandautocrinetransforminggrowthfactorbeta1
‡A
Soluble tumor necrosis factor (TNF) receptor-1 induces apoptosis via reverse TNF signaling and autocrine transforming growth factor-beta1.
‡9
1
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|
919
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|
‡a
solubletcellimmunoglobulinandmucindomaintim1and4generatedbyadisintegrinandmetalloproteaseadam10and17bindtophosphatidylserine
‡A
Soluble T cell immunoglobulin and mucin domain (TIM)-1 and -4 generated by A Disintegrin And Metalloprotease (ADAM)-10 and -17 bind to phosphatidylserine
‡9
1
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|
919
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‡a
solubletcellimmunoglobulinandmucindomain
‡A
Soluble T cell immunoglobulin and mucin domain
‡9
1
|
|
919
|
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|
‡a
solubleinterleukin6receptorsil6rmakesil6rnegativetcelllinerespondtoil6itinhibitstnfproduction
‡A
Soluble interleukin-6 receptor (sIL-6R) makes IL-6R negative T cell line respond to IL-6; it inhibits TNF production.
‡9
1
|
|
919
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|
‡a
solubleil6receptorleadstoaparacrinemodulationoftheil6inducedhepaticacutephaseresponseindoubletransgenicmice
‡A
Soluble IL-6 receptor leads to a paracrine modulation of the IL-6-induced hepatic acute phase response in double transgenic mice.
‡9
1
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|
919
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|
‡a
solubleil6receptorgovernsil6activityinexperimentalarthritisblockadeofarthritisseveritybysolubleglycoprotein130
‡A
Soluble IL-6 Receptor Governs IL-6 Activity in Experimental Arthritis: Blockade of Arthritis Severity by Soluble Glycoprotein 130
‡9
1
|
|
919
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|
‡a
solublehumaninterleukin6receptormodulatesinterleukin6dependentnglycosylationofalpha1proteaseinhibitorsecretedbyhepg2cells
‡A
Soluble human interleukin-6-receptor modulates interleukin-6-dependent N-glycosylation of alpha 1-protease inhibitor secreted by HepG2 cells
‡9
1
|
|
919
|
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|
‡a
solublehumaninterleukin6receptorexpressionininsectcellspurificationandcharacterization
‡A
Soluble human interleukin-6 receptor. Expression in insect cells, purification and characterization
‡9
1
|
|
919
|
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|
‡a
solublegp130isthenaturalinhibitorofsolubleinterleukin6receptortranssignalingresponses
‡A
Soluble gp130 is the natural inhibitor of soluble interleukin-6 receptor transsignaling responses
‡9
1
|
|
919
|
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|
‡a
sleepenhancesil6transsignalinginhumans
‡A
Sleep enhances IL-6 trans-signaling in humans
‡9
1
|
|
919
|
|
|
‡a
sitedirectedmutagenesisofhumancntffunctionalanalysisofrecombinantvariants
‡A
Site-directed mutagenesis of human CNTF: Functional analysis of recombinant variants
‡9
1
|
|
919
|
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|
‡a
signalingofhumanciliaryneurotrophicfactorcntfrevisitedtheinterleukin6receptorcanserveasanalphareceptorforctnf
‡A
Signaling of human ciliary neurotrophic factor (CNTF) revisited. The interleukin-6 receptor can serve as an alpha-receptor for CTNF
‡9
1
|
|
919
|
|
|
‡a
shorttermtnfαsheddingisindependentofcytoplasmicphosphorylationorfurincleavageofadam17
‡A
Short-term TNFα shedding is independent of cytoplasmic phosphorylation or furin cleavage of ADAM17.
‡9
1
|
|
919
|
|
|
‡a
sheddingofinterleukin6receptorandtumornecrosisfactoralphacontributionofthestalksequencetothecleavagepatternoftransmembraneproteins
‡A
Shedding of interleukin-6 receptor and tumor necrosis factor alpha. Contribution of the stalk sequence to the cleavage pattern of transmembrane proteins
‡9
1
|
|
919
|
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|
‡a
sheddingofendogenousinterleukin6receptoril6risgovernedbyadisintegrinandmetalloproteinaseadamproteaseswhileafulllengthil6risoformlocalizestocirculatingmicrovesicles
‡A
Shedding of Endogenous Interleukin-6 Receptor (IL-6R) Is Governed by A Disintegrin and Metalloproteinase (ADAM) Proteases while a Full-length IL-6R Isoform Localizes to Circulating Microvesicles
‡9
1
|
|
919
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|
‡a
senescenceassociatedreleaseoftransmembraneproteinsinvolvesproteolyticprocessingbyadam17andmicrovesicleshedding
‡A
Senescence-associated release of transmembrane proteins involves proteolytic processing by ADAM17 and microvesicle shedding.
‡9
1
|
|
919
|
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|
‡a
semisynthesisofbiologicallyactiveglycoformsofthehumancytokineinterleukin6
‡A
Semisynthesis of Biologically Active Glycoforms of the Human Cytokine Interleukin 6
‡9
1
|
|
919
|
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|
‡a
selectiveblockadeofinterleukin6transsignalingimprovessurvivalinamurinepolymicrobialsepsismodel
‡A
Selective blockade of interleukin-6 trans-signaling improves survival in a murine polymicrobial sepsis model*
‡9
1
|
|
919
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|
‡a
roleofinterleukin6andsolubleil6receptorinregionspecificinductionofastrocyticdifferentiationandneurotrophinexpression
‡A
Role of interleukin-6 and soluble IL-6 receptor in region-specific induction of astrocytic differentiation and neurotrophin expression
‡9
1
|
|
919
|
|
|
‡a
roleofil6transsignalinginccl4inducedliverdamage
‡A
Role of IL-6 trans-signaling in CCl₄induced liver damage
‡9
1
|
|
919
|
|
|
‡a
roleofil6andthesolubleil6receptorininhibitionofvcam1geneexpression
‡A
Role of IL-6 and the soluble IL-6 receptor in inhibition of VCAM-1 gene expression.
‡9
1
|
|
919
|
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|
‡a
rip3akinasepromotingnecroptoticcelldeathmediatesadverseremodellingaftermyocardialinfarction
‡A
RIP3, a kinase promoting necroptotic cell death, mediates adverse remodelling after myocardial infarction
‡9
1
|
|
919
|
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|
‡a
residues7795ofthehumaninterleuken6proteinareresponsibleforreceptorbindingandresidues4156forsignaltransduction
‡A
Residues 77-95 of the human interleuken-6 protein are responsible for receptor binding and residues 41-56 for signal transduction
‡9
1
|
|
919
|
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|
‡a
regulationofthetype2oncostatin1000receptorexpressioninlungderivedepithelialcells
‡A
Regulation of the type II oncostatin M receptor expression in lung-derived epithelial cells
‡9
1
|
|
919
|
|
|
‡a
regulationoffibroticprocessesintheliverbyadamproteases
‡A
Regulation of Fibrotic Processes in the Liver by ADAM Proteases
‡9
1
|
|
919
|
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|
‡a
regulationofendotoxininducedil6productioninliversinusoidalendothelialcellsandkupffercellsbyil10
‡A
Regulation of endotoxin-induced IL-6 production in liver sinusoidal endothelial cells and Kupffer cells by IL-10
‡9
1
|
|
919
|
|
|
‡a
reducedvirusspecificthelpercellinductionbyautologousdendriticcellsinpatientswithchronichepatitisbrestorationbyexogenousinterleukin12
‡A
Reduced virus specific T helper cell induction by autologous dendritic cells in patients with chronic hepatitis B - restoration by exogenous interleukin-12.
‡9
1
|
|
919
|
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|
‡a
recombinantsolublehumaninterleukin6receptorexpressioninescherichiacolirenaturationandpurification
‡A
Recombinant soluble human interleukin-6 receptor. Expression in Escherichia coli, renaturation and purification
‡9
1
|
|
919
|
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|
‡a
recombinantp35frombacteriacanforminterleukinil12butnotil35
‡A
Recombinant p35 from bacteria can form Interleukin (IL-)12, but Not IL-35
‡9
1
|
|
919
|
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|
‡a
recombinantil6treatmentprotectsmicefromorganspecificautoimmunediseasebyil6classicalsignallingdependentil1rainduction
‡A
Recombinant IL-6 treatment protects mice from organ specific autoimmune disease by IL-6 classical signalling-dependent IL-1ra induction
‡9
1
|
|
919
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|
‡a
recombinanthumansinglechainfvantibodiesrecognizinghumaninterleukin6specifictargetingofcytokinesecretingcells
‡A
Recombinant human single chain Fv antibodies recognizing human interleukin-6. Specific targeting of cytokine-secreting cells.
‡9
1
|
|
919
|
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|
‡a
recognitionsequencesandstructuralelementscontributetosheddingsusceptibilityofmembraneproteins
‡A
Recognition sequences and structural elements contribute to shedding susceptibility of membrane proteins.
‡9
1
|
|
919
|
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|
‡a
raid3aninterleukin6receptorbindingaptamerwithpostselectivemodificationresistantaffinity
‡A
RAID3--An interleukin-6 receptor-binding aptamer with post-selective modification-resistant affinity
‡9
1
|
|
919
|
|
|
‡a
radiationinducedlossofsalivaryglandfunctionisdrivenbycellularsenescenceandpreventedbyil6modulation
‡A
Radiation-Induced Loss of Salivary Gland Function Is Driven by Cellular Senescence and Prevented by IL6 Modulation
‡9
1
|
|
919
|
|
|
‡a
proteolyticstepswithinsignalingcascadesmakethesesignalingpathwaysirreversible
‡A
Proteolytic steps within signaling cascades make these signaling pathways irreversible
‡9
1
|
|
919
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|
‡a
proteolyticoriginofthesolublehumanil6rinvivoandadecisiveroleofnglycosylation
‡A
Proteolytic Origin of the Soluble Human IL-6R In Vivo and a Decisive Role of N-Glycosylation
‡9
1
|
|
919
|
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|
‡a
proteolyticcleavagegovernsinterleukin11transsignaling
‡A
Proteolytic Cleavage Governs Interleukin-11 Trans-signaling
‡9
1
|
|
919
|
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|
‡a
proteinkinase100activityisratelimitingforsheddingoftheinterleukin6receptor
‡A
Protein kinase C activity is rate limiting for shedding of the interleukin-6 receptor.
‡9
1
|
|
919
|
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|
‡a
progressiveandcontrolleddevelopmentofmousedendriticcellsfromflt3+cd11b+progenitorsinvitro
‡A
Progressive and controlled development of mouse dendritic cells from Flt3+CD11b+ progenitors in vitro
‡9
1
|
|
919
|
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|
‡a
poreformingtoxinstriggersheddingofreceptorsforinterleukin6andlipopolysaccharide
‡A
Pore-forming toxins trigger shedding of receptors for interleukin 6 and lipopolysaccharide.
‡9
1
|
|
919
|
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|
‡a
polycombgroupproteinbmi1promoteshematopoieticcelldevelopmentfromembryonicstemcells
‡A
Polycomb Group Protein Bmi1 Promotes Hematopoietic Cell Development from Embryonic Stem Cells
‡9
1
|
|
919
|
|
|
‡a
pololikekinase2anoveladam17signalingcomponentregulatestumornecrosisfactorαectodomainshedding
‡A
Polo-like kinase 2, a novel ADAM17 signaling component, regulates tumor necrosis factor α ectodomain shedding
‡9
1
|
|
919
|
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|
‡a
plasticityandcrosstalkofinterleukin6typecytokines
‡A
Plasticity and cross-talk of interleukin 6-type cytokines
‡9
1
|
|
919
|
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|
‡a
pharmaceuticalrelevantcytokinereceptorslessonsfromthe1draftsofthehumanproteome
‡A
Pharmaceutical relevant cytokine receptors: lessons from the first drafts of the human proteome
‡9
1
|
|
919
|
|
|
‡a
peripheralnerveregenerationandngfdependentneuriteoutgrowthofadultsensoryneuronsconvergeonstat3phosphorylationdownstreamofneuropoieticcytokinereceptorgp130
‡A
Peripheral nerve regeneration and NGF-dependent neurite outgrowth of adult sensory neurons converge on STAT3 phosphorylation downstream of neuropoietic cytokine receptor gp130.
‡9
1
|
|
919
|
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|
‡a
peripheralandcentralblockadeofinterleukin6transsignalingdifferentiallyaffectssleeparchitecture
‡A
Peripheral and central blockade of interleukin-6 trans-signaling differentially affects sleep architecture
‡9
1
|
|
919
|
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|
‡a
participationof2serserphetyrrepeatsininterleukin6il6bindingsitesofthehumanil6receptor
‡A
Participation of Two Ser-Ser-Phe-Tyr Repeats in Interleukin-6 (IL-6)-Binding Sites of the Human IL-6 Receptor
‡9
1
|
|
919
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|
‡a
participationof2serserphetyrrepeatsininterleukin6
‡A
Participation of Two Ser-Ser-Phe-Tyr Repeats in Interleukin-6
‡9
1
|
|
919
|
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|
‡a
parathyroidhormoneinducesexpressionandproteolyticprocessingofranklinprimarymurineosteoblasts
‡A
Parathyroid hormone induces expression and proteolytic processing of Rankl in primary murine osteoblasts
‡9
1
|
|
919
|
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|
‡a
overexpressingthesolublegp130fcdoesnotamelioratemethionineandcholinedeficientdietinducednonalcoholicsteatohepatitisinmice
‡A
Over-expressing the soluble gp130-Fc does not ameliorate methionine and choline deficient diet-induced non alcoholic steatohepatitis in mice.
‡9
1
|
|
919
|
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|
‡a
optimizationofretroviralmediatedgenetransfertohumannodscidmouserepopulatingcordbloodcellsthroughasystematicanalysisofprotocolvariables
‡A
Optimization of retroviral-mediated gene transfer to human NOD/SCID mouse repopulating cord blood cells through a systematic analysis of protocol variables.
‡9
1
|
|
919
|
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|
‡a
opposingrolesofgp130mediatedstat3anderk12signalinginliverprogenitorcellmigrationandproliferation
‡A
Opposing roles of gp130-mediated STAT-3 and ERK-1/ 2 signaling in liver progenitor cell migration and proliferation
‡9
1
|
|
919
|
|
|
‡a
oncostatin1000leukaemiainhibitoryfactorandinterleukin6triggerdifferenteffectsonalpha1proteinaseinhibitorsynthesisinhumanlungderivedepithelialcells
‡A
Oncostatin M, leukaemia-inhibitory factor and interleukin 6 trigger different effects on alpha1-proteinase inhibitor synthesis in human lung-derived epithelial cells
‡9
1
|
|
919
|
|
|
‡a
oncogenicdeletionmutantsofgp130signalfromintracellularcompartments
‡A
Oncogenic deletion mutants of gp130 signal from intracellular compartments
‡9
1
|
|
919
|
|
|
‡a
novelregulatorymechanismsforgenerationofthesolubleleptinreceptorimplicationsforleptinaction
‡A
Novel regulatory mechanisms for generation of the soluble leptin receptor: implications for leptin action
‡9
1
|
|
919
|
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|
‡a
novelpotentprolinebasedmetalloproteinaseinhibitorsdesignradiosynthesisand1invivoevaluationasradiotracersforpositronemissiontomography
‡A
Novel Potent Proline-Based Metalloproteinase Inhibitors: Design, (Radio)Synthesis, and First in Vivo Evaluation as Radiotracers for Positron Emission Tomography
‡9
1
|
|
919
|
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|
‡a
novelpathogenicmechanismofmicrobialmetalloproteinasesliberationofmembraneanchoredmoleculesinbiologicallyactiveformexemplifiedbystudieswiththehumaninterleukin6receptor
‡A
Novel pathogenic mechanism of microbial metalloproteinases: liberation of membrane-anchored molecules in biologically active form exemplified by studies with the human interleukin-6 receptor
‡9
1
|
|
919
|
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|
‡a
novelpathtoil6transsignalingthroughthrombininducedsolubleil6receptorreleasebyplatelets
‡A
Novel path to IL-6 trans-signaling through thrombin-induced soluble IL-6 receptor release by platelets
‡9
1
|
|
919
|
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|
‡a
novelpathtoactivationofvascularsmoothmusclecellsupregulationofgp130createsanautocrineactivationloopbyil6anditssolublereceptor
‡A
Novel path to activation of vascular smooth muscle cells: up-regulation of gp130 creates an autocrine activation loop by IL-6 and its soluble receptor
‡9
1
|
|
919
|
|
|
‡a
notchactivationviagp130stat3signalingconfersresistancetochemoradiotherapy
‡A
NOTCH Activation via gp130/STAT3 Signaling Confers Resistance to Chemoradiotherapy
‡9
1
|
|
919
|
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|
‡a
notinterferonbutinterleukin6controlsearlygeneexpressioninhepatitisbvirusinfection
‡A
Not interferon, but interleukin-6 controls early gene expression in hepatitis B virus infection
‡9
1
|
|
919
|
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|
‡a
noinhibitionofil27signalingbysolublegp130
‡A
No inhibition of IL-27 signaling by soluble gp130.
‡9
1
|
|
919
|
|
|
‡a
newperspectivesonthedesignofcytokinesandgrowthfactors
‡A
New perspectives on the design of cytokines and growth factors.
‡9
1
|
|
919
|
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|
‡a
newinsightsintotheroleandsignallingprocessesofgp130
‡A
New insights into the role and signalling processes of gp130.
‡9
1
|
|
919
|
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|
‡a
newdevelopmentsinil6dependentbiologyandtherapywheredowestandandwhataretheoptions
‡A
New developments in IL-6 dependent biology and therapy: where do we stand and what are the options?
‡9
1
|
|
919
|
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|
‡a
naturalsolubleinterleukin15ralphaisgeneratedbycleavagethatinvolvesthetumornecrosisfactoralphaconvertingenzymetaceadam17
‡A
Natural soluble interleukin-15Ralpha is generated by cleavage that involves the tumor necrosis factor-alpha-converting enzyme (TACE/ADAM17).
‡9
1
|
|
919
|
|
|
‡a
naturalsolubleinterleukin15ralphaisgeneratedbycleavagethatinvolvesthetumornecrosisfactoralphaconvertingenzyme
‡A
Natural soluble interleukin-15Ralpha is generated by cleavage that involves the tumor necrosis factor-alpha-converting enzyme
‡9
1
|
|
919
|
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|
‡a
nlinkedglycosylationisessentialforthestabilitybutnotthesignalingfunctionoftheinterleukin6signaltransducerglycoprotein130
‡A
N-linked glycosylation is essential for the stability but not the signaling function of the interleukin-6 signal transducer glycoprotein 130.
‡9
1
|
|
919
|
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|
‡a
myeloidadisintegrinandmetalloproteinasedomain10deficiencymodulatesatheroscleroticplaquecompositionbyshiftingthebalancefrominflammationtowardfibrosis
‡A
Myeloid A disintegrin and metalloproteinase domain 10 deficiency modulates atherosclerotic plaque composition by shifting the balance from inflammation toward fibrosis.
‡9
1
|
|
919
|
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|
‡a
mycobacteriumsimiaeinfectionin2unrelatedpatientswithdifferentformsofinheritedifnγr2deficiency
‡A
Mycobacterium simiae infection in two unrelated patients with different forms of inherited IFN-γR2 deficiency
‡9
1
|
|
919
|
|
|
‡a
murinestromalcellsproducinghyperinterleukin6andflt3ligandsupportexpansionofearlyhumanhematopoieticprogenitorcellswithoutneedofexogenousgrowthfactors
‡A
Murine stromal cells producing hyper-interleukin-6 and Flt3 ligand support expansion of early human hematopoietic progenitor cells without need of exogenous growth factors
‡9
1
|
|
919
|
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|
‡a
multilevelregulationofil6rbyil6sil6rfusionproteinaccordingtotheprimitivenessofperipheralbloodderivedcd133+cells
‡A
Multilevel regulation of IL-6R by IL-6-sIL-6R fusion protein according to the primitiveness of peripheral blood-derived CD133+ cells
‡9
1
|
|
919
|
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|
‡a
1h15nand13cbackboneassignmentofthecarboxylterminaldomainofthecytokinebindingmoduleoftheinterleukin6receptor
‡A
1H, 15N and 13C backbone assignment of the carboxyl terminal domain of the cytokine binding module of the interleukin-6 receptor.
‡9
1
|
|
919
|
|
|
‡a
bioactivedesignercytokineforhumanhematopoieticprogenitorcellexpansion
‡A
A bioactive designer cytokine for human hematopoietic progenitor cell expansion
‡9
1
|
|
919
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|
|
‡a
designerhyperinterleukin11h11isabiologicallyactivecytokine
‡A
A designer hyper interleukin 11 (H11) is a biologically active cytokine.
‡9
1
|
|
919
|
|
|
‡a
disintegrinandmetalloprotease10
‡A
A disintegrin and metalloprotease 10
‡9
1
|
|
919
|
|
|
‡a
disintegrinandmetalloprotease10adam10isacentralregulatorofmurinelivertissuehomeostasis
‡A
A disintegrin and metalloprotease 10 (ADAM10) is a central regulator of murine liver tissue homeostasis
‡9
1
|
|
919
|
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|
‡a
disintegrinandmetalloprotease17dynamicinteractionsequencethesweettoothforthehumaninterleukin6receptor
‡A
A disintegrin and metalloprotease 17 dynamic interaction sequence, the sweet tooth for the human interleukin 6 receptor
‡9
1
|
|
919
|
|
|
‡a
disintegrinandmetalloproteaseadam10andadam17aremajorsheddasesoftcellimmunoglobulinandmucindomain3tim3
‡A
A disintegrin and metalloprotease (ADAM) 10 and ADAM17 are major sheddases of T cell immunoglobulin and mucin domain 3 (Tim-3)
‡9
1
|
|
919
|
|
|
‡a
mucusdetachmentbyhostmetalloproteasemeprinβrequiressheddingofitsinactiveproformwhichisabrogatedbythepathogenicproteasergpb
‡A
Mucus Detachment by Host Metalloprotease Meprin β Requires Shedding of Its Inactive Pro-form, which Is Abrogated by the Pathogenic Protease RgpB.
‡9
1
|
|
919
|
|
|
‡a
mtnfreversesignallinginducedbytnfαantagonistsinvolvesagdf1dependentpathwayimplicationsforcrohnsdisease
‡A
mTNF reverse signalling induced by TNFα antagonists involves a GDF-1 dependent pathway: implications for Crohn's disease.
‡9
1
|
|
919
|
|
|
‡a
mouseneutrophilsexpressthedecoytype2interleukin1receptoril1r2constitutivelyandinacuteinflammatoryconditions
‡A
Mouse neutrophils express the decoy type 2 interleukin-1 receptor (IL-1R2) constitutively and in acute inflammatory conditions
‡9
1
|
|
919
|
|
|
‡a
mouseneutrophilsexpressthedecoytype2interleukin1receptor
‡A
Mouse neutrophils express the decoy type 2 interleukin-1 receptor
‡9
1
|
|
919
|
|
|
‡a
moreaboutgeneticallymodifiedtumourvaccines
‡A
More about genetically modified tumour vaccines.
‡9
1
|
|
919
|
|
|
‡a
molecularcloningofmouseproteinkinase100pkccdnafromswiss3t3fibroblasts
‡A
Molecular cloning of mouse protein kinase C (PKC) cDNA from Swiss 3T3 fibroblasts.
‡9
1
|
|
919
|
|
|
‡a
molecularcloningandexpressionofanintracellularserpinanelastaseinhibitorfromhorseleucocytes
‡A
Molecular cloning and expression of an intracellular serpin: an elastase inhibitor from horse leucocytes
‡9
1
|
|
919
|
|
|
‡a
modellingirf8deficienthumanhematopoiesisanddendriticcelldevelopmentwithengineeredipscells
‡A
Modelling IRF8 Deficient Human Hematopoiesis and Dendritic Cell Development with Engineered iPS Cells
‡9
1
|
|
919
|
|
|
‡a
modelbasedtargetingofil6inducedinflammatoryresponsesinculturedprimaryhepatocytestoimproveapplicationofthejakinhibitorruxolitinib
‡A
Model Based Targeting of IL-6-Induced Inflammatory Responses in Cultured Primary Hepatocytes to Improve Application of the JAK Inhibitor Ruxolitinib.
‡9
1
|
|
919
|
|
|
‡a
microheterogeneityofhumaninterleukin6synthesizedbytransfectednih3t3cellscomparisonwithhumanmonocytesfibroblastsandendothelialcells
‡A
Microheterogeneity of human interleukin 6 synthesized by transfected NIH/3T3 cells: comparison with human monocytes, fibroblasts and endothelial cells.
‡9
1
|
|
919
|
|
|
‡a
metalloproteasemediatedtumorcellsheddingofb7h6theligandofthenaturalkillercellactivatingreceptornkp30
‡A
Metalloprotease-mediated tumor cell shedding of B7-H6, the ligand of the natural killer cell-activating receptor NKp30.
‡9
1
|
|
919
|
|
|
‡a
meprinmetalloproteasesgeneratebiologicallyactivesolubleinterleukin6receptortoinducetranssignaling
‡A
Meprin Metalloproteases Generate Biologically Active Soluble Interleukin-6 Receptor to Induce Trans-Signaling
‡9
1
|
|
919
|
|
|
‡a
membraneboundandsolubleinterleukin6receptorstudiesonstructureregulationofexpressionandsignaltransduction
‡A
Membrane-bound and soluble interleukin-6 receptor: studies on structure, regulation of expression, and signal transduction.
‡9
1
|
|
919
|
|
|
‡a
mechanisticinsightsintoatimp3sensitivepathwayconstitutivelyengagedintheregulationofcerebralhemodynamics
‡A
Mechanistic insights into a TIMP3-sensitive pathway constitutively engaged in the regulation of cerebral hemodynamics
‡9
1
|
|
919
|
|
|
‡a
maintenanceofpluripotencyinhumanembryonicstemcellsisstat3independent
‡A
Maintenance of pluripotency in human embryonic stem cells is STAT3 independent
‡9
1
|
|
919
|
|
|
‡a
lossofp53functionactivatesjak2stat3signalingtopromotepancreatictumorgrowthstromamodificationandgemcitabineresistanceinmiceandisassociatedwithpatientsurvival
‡A
Loss of P53 Function Activates JAK2-STAT3 Signaling to Promote Pancreatic Tumor Growth, Stroma Modification, and Gemcitabine Resistance in Mice and Is Associated With Patient Survival.
‡9
1
|
|
919
|
|
|
‡a
lossofcd4+tcellil6rexpressionduringinflammationunderlinesaroleforil6transsignalinginthelocalmaintenanceofth17cells
‡A
Loss of CD4+ T cell IL-6R expression during inflammation underlines a role for IL-6 trans signaling in the local maintenance of Th17 cells
‡9
1
|
|
919
|
|
|
‡a
longtermsurvivalofhighriskmelanomapatientsimmunizedwithahyperil6modifiedallogeneicwholecellvaccineaftercompleteresection
‡A
Long-term survival of high-risk melanoma patients immunized with a Hyper-IL-6-modified allogeneic whole-cell vaccine after complete resection
‡9
1
|
|
919
|
|
|
‡a
localblockadeofil6rsignalinginduceslungcd4+tcellapoptosisinamurinemodelofasthmaviaregulatorytcells
‡A
Local blockade of IL-6R signaling induces lung CD4+ T cell apoptosis in a murine model of asthma via regulatory T cells
‡9
1
|
|
919
|
|
|
‡a
liversinusoidalendothelialcellcrossprimingissupportedbycd4tcellderivedil2
‡A
Liver sinusoidal endothelial cell cross-priming is supported by CD4 T cell-derived IL-2.
‡9
1
|
|
919
|
|
|
‡a
liverregenerationinducedbyadesignerhumanil6sil6rfusionproteinreversesseverehepatocellularinjury
‡A
Liver regeneration induced by a designer human IL-6/sIL-6R fusion protein reverses severe hepatocellular injury.
‡9
1
|
|
919
|
|
|
‡a
ligandreceptorsignalingthresholdlistmodelaccountsforgp130mediatedembryonicstemcellselfrenewalresponsestolifandhil6
‡A
Ligand/Receptor Signaling Threshold (LIST) Model Accounts for gp130-Mediated Embryonic Stem Cell Self-Renewal Responses to LIF and HIL-6
‡9
1
|
|
919
|
|
|
‡a
ligandreceptorsignalingthreshold
‡A
Ligand/Receptor Signaling Threshold
‡9
1
|
|
919
|
|
|
‡a
leucine58intheputative5helicalregionofhumaninterleukinil6isimportantforactivationoftheil6signaltransducergp130
‡A
Leucine-58 in the putative 5th helical region of human interleukin (IL)-6 is important for activation of the IL-6 signal transducer, gp130
‡9
1
|
|
919
|
|
|
‡a
laboratorydiagnosticsofmurinebloodfordetectionofmousecytomegalovirus1905inducedhepatitis
‡A
Laboratory diagnostics of murine blood for detection of mouse cytomegalovirus (MCMV)-induced hepatitis
‡9
1
|
|
919
|
|
|
‡a
laboratorydiagnosticsofmurinebloodfordetectionofmousecytomegalovirus
‡A
Laboratory diagnostics of murine blood for detection of mouse cytomegalovirus
‡9
1
|
|
919
|
|
|
‡a
l1issequentiallyprocessedby2differentlyactivatedmetalloproteasesandpresenilingammasecretaseandregulatesneuralcelladhesioncellmigrationandneuriteoutgrowth
‡A
L1 is sequentially processed by two differently activated metalloproteases and presenilin/gamma-secretase and regulates neural cell adhesion, cell migration, and neurite outgrowth
‡9
1
|
|
919
|
|
|
‡a
kshvencodedvil6collaborateswithderegulated100myctodriveplasmablasticneoplasmsinmice
‡A
KSHV-encoded vIL-6 collaborates with deregulated c-Myc to drive plasmablastic neoplasms in mice.
‡9
1
|
|
919
|
|
|
‡a
jointreconstitutedsignalingoftheil6receptorviaextracellularvesicles
‡A
Joint Reconstituted Signaling of the IL-6 Receptor via Extracellular Vesicles
‡9
1
|
|
919
|
|
|
‡a
isinterleukin6receptorblockadetheholygrailforinflammatorydiseases
‡A
Is Interleukin-6 Receptor Blockade the Holy Grail for Inflammatory Diseases?
‡9
1
|
|
919
|
|
|
‡a
introductiontostemcellbiologyinvitrothresholdtothefuture
‡A
Introduction to stem cell biology in vitro. Threshold to the future.
‡9
1
|
|
919
|
|
|
‡a
intravitrealinjectionofantiinterleukinil6antibodyattenuatesexperimentalautoimmuneuveitisinmice
‡A
Intravitreal injection of anti-Interleukin (IL)-6 antibody attenuates experimental autoimmune uveitis in mice
‡9
1
|
|
919
|
|
|
‡a
intravitrealinjectionofantiinterleukin
‡A
Intravitreal injection of anti-Interleukin
‡9
1
|
|
919
|
|
|
‡a
intracellularretentionofinterleukin6abrogatessignaling
‡A
Intracellular retention of interleukin-6 abrogates signaling.
‡9
1
|
|
919
|
|
|
‡a
interplaybetweenifngammaandil6signalinggovernsneutrophiltraffickingandapoptosisduringacuteinflammation
‡A
Interplay between IFN-gamma and IL-6 signaling governs neutrophil trafficking and apoptosis during acute inflammation
‡9
1
|
|
919
|
|
|
‡a
interleukin6wntinteractionsinrheumatoidarthritisinterleukin6inhibitswntsignalinginsynovialfibroblastsandosteoblasts
‡A
Interleukin 6/Wnt interactions in rheumatoid arthritis: interleukin 6 inhibits Wnt signaling in synovial fibroblasts and osteoblasts.
‡9
1
|
|
946
|
|
|
‡a
b
‡9
1
|
|
996
|
|
|
‡2
ISNI|0000000047525358
|
|
996
|
|
|
‡2
SUDOC|142388483
|
|
996
|
|
|
‡2
NLA|000064460906
|
|
996
|
|
|
‡2
DNB|133470075
|
|
996
|
|
|
‡2
SUDOC|193735717
|
|
996
|
|
|
‡2
RERO|A006315924
|
|
996
|
|
|
‡2
LC|n 2021012605
|
|
996
|
|
|
‡2
DNB|134928318
|
|
996
|
|
|
‡2
DNB|1322757933
|
|
996
|
|
|
‡2
LC|no2009002241
|
|
996
|
|
|
‡2
LC|n 78023458
|
|
996
|
|
|
‡2
DNB|134913434
|
|
996
|
|
|
‡2
NLA|000069057803
|
|
996
|
|
|
‡2
LC|no2002107717
|
|
996
|
|
|
‡2
DNB|1275779301
|
|
996
|
|
|
‡2
ISNI|0000000403220770
|
|
996
|
|
|
‡2
ISNI|0000000453024778
|
|
996
|
|
|
‡2
DNB|118557815
|
|
996
|
|
|
‡2
SUDOC|164986251
|
|
996
|
|
|
‡2
DNB|1236372115
|
|
996
|
|
|
‡2
DNB|136597858
|
|
996
|
|
|
‡2
RERO|A027773357
|
|
996
|
|
|
‡2
DBC|87097969711324
|
|
996
|
|
|
‡2
LC|nr2001040088
|
|
996
|
|
|
‡2
SUDOC|264173228
|
|
996
|
|
|
‡2
LC|n 2007054023
|
|
996
|
|
|
‡2
ISNI|0000000019926074
|
|
996
|
|
|
‡2
DNB|1255376899
|
|
996
|
|
|
‡2
ISNI|0000000027835746
|
|
996
|
|
|
‡2
SUDOC|275202593
|
|
996
|
|
|
‡2
LC|no2017110440
|
|
996
|
|
|
‡2
DNB|1161756043
|
|
996
|
|
|
‡2
ISNI|0000000498574191
|
|
996
|
|
|
‡2
LC|n 80053460
|
|
996
|
|
|
‡2
ISNI|0000000044930796
|
|
996
|
|
|
‡2
LC|n 87921445
|
|
996
|
|
|
‡2
N6I|vtls000071392
|
|
996
|
|
|
‡2
BNE|XX1696139
|
|
996
|
|
|
‡2
LC|no2018170632
|
|
996
|
|
|
‡2
DNB|1127557122
|
|
996
|
|
|
‡2
SZ|118557815
|
|
996
|
|
|
‡2
ISNI|0000000032395773
|
|
996
|
|
|
‡2
DNB|141244461
|
|
996
|
|
|
‡2
DNB|135245176
|
|
996
|
|
|
‡2
BNE|XX5752472
|
|
996
|
|
|
‡2
ISNI|000000005719058X
|
|
996
|
|
|
‡2
BIBSYS|7052314
|
|
996
|
|
|
‡2
LC|no2017101593
|
|
996
|
|
|
‡2
DNB|173680658
|
|
996
|
|
|
‡2
BNF|15040510
|
|
996
|
|
|
‡2
BIBSYS|3109133
|
|
996
|
|
|
‡2
DNB|138266484
|
|
996
|
|
|
‡2
ISNI|0000000109833197
|
|
997
|
|
|
‡a
1900 0 flourished 0000 0
‡9
1
|
|
998
|
|
|
‡a
Rose-John, Stefan
‡2
DNB|140944362
‡3
suggested
‡3
viafid
|
|
998
|
|
|
‡a
Rose-John, Stefan
‡2
NSK|000721161
‡3
exact title: (1.00, 'interleukin6wntinteractionsinrheumatoidarthritisinterleukin6inhibitswntsignalinginsynovialfibroblastsandosteoblasts', 'interleukin6wntinteractionsinrheumatoidarthritisinterleukin6inhibitswntsignalinginsynovialfibroblastsandosteoblasts')
|
|
998
|
|
|
‡a
Rose-John, Stefan
‡2
ISNI|0000000077993873
‡3
suggested
|
|
998
|
|
|
‡a
Rose-John, Stefan
‡2
PLWABN|9810541510705606
‡3
viafid
|
