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WKP|Q83610012
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0 |
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C-H Zhang
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onderzoeker
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nl
|
670
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‡a
Author's Discovery and structure-activity analysis of 4-((5-nitropyrimidin-4-yl)amino)benzimidamide derivatives as novel protein arginine methyltransferase 1 (PRMT1) inhibitors
|
670
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‡a
Author's Discovery of 6-phenylimidazo[2,1-b]thiazole derivatives as a new type of FLT3 inhibitors
|
670
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‡a
Author's Discovery of KDM5A inhibitors: Homology modeling, virtual screening and structure-activity relationship analysis
|
670
|
|
|
‡a
Author's Discovery of the novel potent and selective FLT3 inhibitor 1-{5-[7-(3- morpholinopropoxy)quinazolin-4-ylthio]-[1,3,4]thiadiazol-2-yl}-3-p-tolylurea and its anti-acute myeloid leukemia (AML) activities in vitro and in vivo.
|
670
|
|
|
‡a
Author's Preclinical Evaluation of a Novel Orally Available SRC/Raf/VEGFR2 Inhibitor, SKLB646, in the Treatment of Triple-Negative Breast Cancer
|
670
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‡a
Author's Progress of small molecular inhibitors in the development of anti-influenza virus agents
|
670
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‡a
Author's Retrieving novel C5aR antagonists using a hybrid ligand-based virtual screening protocol based on SVM classification and pharmacophore models.
|
670
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|
|
‡a
Author's SKLB1028, a novel oral multikinase inhibitor of EGFR, FLT3 and Abl, displays exceptional activity in models of FLT3-driven AML and considerable potency in models of CML harboring Abl mutants.
|
670
|
|
|
‡a
Author's Structural modification of an EGFR inhibitor that showed weak off-target activity against RET leading to the discovery of a potent RET inhibitor
|
670
|
|
|
‡a
Author's Structural optimization and structure-activity relationships of N2-(4-(4-Methylpiperazin-1-yl)phenyl)-N8-phenyl-9H-purine-2,8-diamine derivatives, a new class of reversible kinase inhibitors targeting both EGFR-activating and resistance mutations.
|
909
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|
‡a
(orcid) 0000000245799202
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1
|
919
|
|
|
‡a
structuralmodificationofanegfrinhibitorthatshowedweakofftargetactivityagainstretleadingtothediscoveryofapotentretinhibitor
‡A
Structural modification of an EGFR inhibitor that showed weak off-target activity against RET leading to the discovery of a potent RET inhibitor
‡9
1
|
919
|
|
|
‡a
structuraloptimizationandstructureactivityrelationshipsofn244methylpiperazin1ylphenyln8phenyl9hpurine28diaminederivativesanewclassofreversiblekinaseinhibitorstargetingbothegfractivatingandresistancemutations
‡A
Structural optimization and structure-activity relationships of N2-(4-(4-Methylpiperazin-1-yl)phenyl)-N8-phenyl-9H-purine-2,8-diamine derivatives, a new class of reversible kinase inhibitors targeting both EGFR-activating and resistance mutations.
‡9
1
|
919
|
|
|
‡a
discoveryofkdm5ainhibitorshomologymodelingvirtualscreeningandstructureactivityrelationshipanalysis
‡A
Discovery of KDM5A inhibitors: Homology modeling, virtual screening and structure-activity relationship analysis
‡9
1
|
919
|
|
|
‡a
discoveryof6phenylimidazothiazolederivativesasanewtypeofflt3inhibitors
‡A
Discovery of 6-phenylimidazo[2,1-b]thiazole derivatives as a new type of FLT3 inhibitors
‡9
1
|
919
|
|
|
‡a
discoveryandstructureactivityanalysisof45nitropyrimidin4ylaminobenzimidamidederivativesasnovelproteinargininemethyltransferase1prmt1inhibitors
‡A
Discovery and structure-activity analysis of 4-((5-nitropyrimidin-4-yl)amino)benzimidamide derivatives as novel protein arginine methyltransferase 1 (PRMT1) inhibitors
‡9
1
|
919
|
|
|
‡a
discoveryofthenovelpotentandselectiveflt3inhibitor15thiadiazol2yl3ptolylureaanditsantiacutemyeloidleukemiaamlactivitiesinvitroandinvivo
‡A
Discovery of the novel potent and selective FLT3 inhibitor 1-{5-[7-(3- morpholinopropoxy)quinazolin-4-ylthio]-[1,3,4]thiadiazol-2-yl}-3-p-tolylurea and its anti-acute myeloid leukemia (AML) activities in vitro and in vivo.
‡9
1
|
919
|
|
|
‡a
preclinicalevaluationofanovelorallyavailablesrcrafvegfr2inhibitorsklb646inthetreatmentoftriplenegativebreastcancer
‡A
Preclinical Evaluation of a Novel Orally Available SRC/Raf/VEGFR2 Inhibitor, SKLB646, in the Treatment of Triple-Negative Breast Cancer
‡9
1
|
919
|
|
|
‡a
progressofsmallmolecularinhibitorsinthedevelopmentofantiinfluenzavirusagents
‡A
Progress of small molecular inhibitors in the development of anti-influenza virus agents
‡9
1
|
919
|
|
|
‡a
retrievingnovelc5arantagonistsusingahybridligandbasedvirtualscreeningprotocolbasedonsvmclassificationandpharmacophoremodels
‡A
Retrieving novel C5aR antagonists using a hybrid ligand-based virtual screening protocol based on SVM classification and pharmacophore models.
‡9
1
|
919
|
|
|
‡a
sklb1028anoveloralmultikinaseinhibitorofegfrflt3andabldisplaysexceptionalactivityinmodelsofflt3drivenamlandconsiderablepotencyinmodelsof950harboringablmutants
‡A
SKLB1028, a novel oral multikinase inhibitor of EGFR, FLT3 and Abl, displays exceptional activity in models of FLT3-driven AML and considerable potency in models of CML harboring Abl mutants.
‡9
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|
‡2
ISNI|0000000063486686
|
996
|
|
|
‡2
ISNI|0000000064176698
|
996
|
|
|
‡2
RERO|A024805009
|
996
|
|
|
‡2
CYT|AC000166922
|
996
|
|
|
‡2
LC|nr 93050264
|
996
|
|
|
‡2
ISNI|0000000357043506
|
996
|
|
|
‡2
LC|n 2016015905
|
996
|
|
|
‡2
CYT|AC000649453
|
996
|
|
|
‡2
SUDOC|131470558
|
996
|
|
|
‡2
DNB|172610036
|
996
|
|
|
‡2
ISNI|000000003791523X
|
996
|
|
|
‡2
LC|no2024067116
|
996
|
|
|
‡2
CYT|AC000475092
|
996
|
|
|
‡2
CYT|AC000375441
|
996
|
|
|
‡2
ISNI|000000011555563X
|
996
|
|
|
‡2
CYT|AC000186829
|
996
|
|
|
‡2
ISNI|0000000029292079
|
996
|
|
|
‡2
DNB|1237924286
|
996
|
|
|
‡2
DNB|171897927
|
996
|
|
|
‡2
DNB|128062857X
|
996
|
|
|
‡2
LC|nr 93038918
|
996
|
|
|
‡2
LC|no2012143290
|
996
|
|
|
‡2
DNB|1212462335
|
996
|
|
|
‡2
LC|no2001072344
|
996
|
|
|
‡2
ISNI|0000000075394340
|
996
|
|
|
‡2
BNF|16897489
|
996
|
|
|
‡2
DNB|130639583
|
996
|
|
|
‡2
DNB|123943485
|
996
|
|
|
‡2
ISNI|0000000458364210
|
996
|
|
|
‡2
LC|n 2011086958
|
996
|
|
|
‡2
NDL|00485790
|
996
|
|
|
‡2
NTA|393855562
|
996
|
|
|
‡2
LC|n 2006071538
|
996
|
|
|
‡2
BNF|14446317
|
997
|
|
|
‡a
0 0 lived 0 0
‡9
1
|