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developmentofbromotagabumpandholeprotacsystemtoinducepotentrapidandselectivedegradationoftaggedtargetproteins
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Development of BromoTag: A “Bump-and-Hole”–PROTAC System to Induce Potent, Rapid, and Selective Degradation of Tagged Target Proteins
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1
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optimizationofabumpandholeapproachtoalleleselectivebetbromodomaininhibition
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Optimization of a "bump-and-hole" approach to allele-selective BET bromodomain inhibition.
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1
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trivalentprotacsenhanceproteindegradationviacombinedavidityandcooperativity
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Trivalent PROTACs enhance protein degradation via combined avidity and cooperativity
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1