"Make Room! Make Room! is set in the year 1999 and the world has become a grim and terribly overpopulated place, bleak and foreboding. This sets the premise for Harrison's novel, and fans of his earlier more comic works may be surprised at the seriousness of this novel. Although Harrison's fears did not become a reality for the inhabitants of New York or the rest of the United States, the novel remains nonetheless a gripping, thought-provoking work about privacy, deprivation, and desperation.

A teeming New York City and a detective's pursuit of a killer and nefarious racketeer comprise this novel. While the novel contains elements of classic detective fiction--the hard-boiled protagonist, the seductive mistress, the portraits of corruption and perfidy--Harrison's true concern is less the story itself and more the opportunity the story offers to give the reader a glance at a dismal and broken world. The state of overpopulation has altered life in innumerable ways, and Harrison is keenly interested in documenting the catastrophic effects of this burden on all human relationships. "